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Murcko scaffold

Ring system with 3 rings and 24 atoms

65 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
65
With full pages
8
Scaffold SMILES

O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCCCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCCCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

2,4-Dichloro-N-[2-methoxy-5-(trifluoromethyl)phenyl]-5-piperidin-1-ylsulfonylbenzamide chemical structure, C20H19Cl2F3N2O4S, CAS 354537-63-6
2,4-Dichloro-N-[2-methoxy-5-(trifluoromethyl)phenyl]-5-piperidin-1-ylsulfonylbenzamide
CAS 354537-63-6C20H19Cl2F3N2O4S
4-Bromo-N-(4-bromophenyl)-3-piperidin-1-ylsulfonylbenzamide chemical structure, C18H18Br2N2O3S, CAS 313258-93-4
4-Bromo-N-(4-bromophenyl)-3-piperidin-1-ylsulfonylbenzamide
CAS 313258-93-4C18H18Br2N2O3S
N-(4-Chlorophenyl)-3-(1-piperidinylsulfonyl)benzamide chemical structure, C18H19ClN2O3S, CAS 302603-73-2
N-(4-Chlorophenyl)-3-(1-piperidinylsulfonyl)benzamide
CAS 302603-73-2C18H19ClN2O3S
N-(3-Fluorophenyl)-3-(1-piperidinylsulfonyl)benzamide chemical structure, C18H19FN2O3S, CAS 313259-52-8
N-(3-Fluorophenyl)-3-(1-piperidinylsulfonyl)benzamide
CAS 313259-52-8C18H19FN2O3S
2,4-Dichloro-N-phenyl-5-(1-piperidinylsulfonyl)benzamide chemical structure, C18H18Cl2N2O3S, CAS 313261-06-2
2,4-Dichloro-N-phenyl-5-(1-piperidinylsulfonyl)benzamide
CAS 313261-06-2C18H18Cl2N2O3S
N-(2-Methoxyphenyl)-3-(piperidin-1-ylsulfonyl)benzamide chemical structure, C19H22N2O4S, CAS 313259-85-7
N-(2-Methoxyphenyl)-3-(piperidin-1-ylsulfonyl)benzamide
CAS 313259-85-7C19H22N2O4S
4-Bromo-N-(3-hydroxyphenyl)-3-piperidin-1-ylsulfonylbenzamide chemical structure, C18H19BrN2O4S, CAS 296801-08-6
4-Bromo-N-(3-hydroxyphenyl)-3-piperidin-1-ylsulfonylbenzamide
CAS 296801-08-6C18H19BrN2O4S
4-Methyl-N-phenyl-3-(piperidine-1-sulfonyl)-benzamide chemical structure, C19H22N2O3S, CAS 331653-69-1
4-Methyl-N-phenyl-3-(piperidine-1-sulfonyl)-benzamide
CAS 331653-69-1C19H22N2O3S
4-[4-Chloro-3-(piperidine-1-sulfonyl)benzamido]benzoic acid chemical structure, C19H19ClN2O5S, CAS 5253-14-5
4-[4-Chloro-3-(piperidine-1-sulfonyl)benzamido]benzoic acid
CAS 5253-14-5C19H19ClN2O5S
N-(4-Bromophenyl)-3-(piperidinosulfonyl)benzamide chemical structure, C18H19BrN2O3S, CAS 302955-84-6
N-(4-Bromophenyl)-3-(piperidinosulfonyl)benzamide
CAS 302955-84-6C18H19BrN2O3S
N-(3-Chlorophenyl)-4-methyl-3-(1-piperidinylsulfonyl)benzamide chemical structure, C19H21ClN2O3S, CAS 420832-24-2
N-(3-Chlorophenyl)-4-methyl-3-(1-piperidinylsulfonyl)benzamide
CAS 420832-24-2C19H21ClN2O3S
N-(3-Chlorophenyl)-3-(piperidin-1-ylsulfonyl)benzamide chemical structure, C18H19ClN2O3S, CAS 330445-63-1
N-(3-Chlorophenyl)-3-(piperidin-1-ylsulfonyl)benzamide
CAS 330445-63-1C18H19ClN2O3S
N-(5-Chloro-2-hydroxyphenyl)-3-(1-piperidinylsulfonyl)benzamide chemical structure, C18H19ClN2O4S, CAS 823837-22-5
N-(5-Chloro-2-hydroxyphenyl)-3-(1-piperidinylsulfonyl)benzamide
CAS 823837-22-5C18H19ClN2O4S
2-Bromo-N-(3-methylphenyl)-5-piperidin-1-ylsulfonylbenzamide chemical structure, C19H21BrN2O3S, CAS 431883-74-8
2-Bromo-N-(3-methylphenyl)-5-piperidin-1-ylsulfonylbenzamide
CAS 431883-74-8C19H21BrN2O3S
N-(3-Hydroxyphenyl)-4-methyl-3-piperidin-1-ylsulfonylbenzamide chemical structure, C19H22N2O4S, CAS 313685-52-8
N-(3-Hydroxyphenyl)-4-methyl-3-piperidin-1-ylsulfonylbenzamide
CAS 313685-52-8C19H22N2O4S
N-(2-tert-Butylphenyl)-2,4-dichloro-5-piperidin-1-ylsulfonylbenzamide chemical structure, C22H26Cl2N2O3S, CAS 445288-87-9
N-(2-tert-Butylphenyl)-2,4-dichloro-5-piperidin-1-ylsulfonylbenzamide
CAS 445288-87-9C22H26Cl2N2O3S
N-(4-((Difluoromethyl)sulfonyl)phenyl)-3-(piperidin-1-ylsulfonyl)benzamide chemical structure, C19H20F2N2O5S2, CAS 690249-32-2
N-(4-((Difluoromethyl)sulfonyl)phenyl)-3-(piperidin-1-ylsulfonyl)benzamide
CAS 690249-32-2C19H20F2N2O5S2
N-(4-Fluorophenyl)-3-(piperidin-1-ylsulfonyl)benzamide chemical structure, C18H19FN2O3S, CAS 325720-66-9
N-(4-Fluorophenyl)-3-(piperidin-1-ylsulfonyl)benzamide
CAS 325720-66-9C18H19FN2O3S
N-(2-Methoxyphenyl)-4-methyl-3-(piperidine-1-sulfonyl)benzamide chemical structure, C20H24N2O4S, CAS 870141-47-2
N-(2-Methoxyphenyl)-4-methyl-3-(piperidine-1-sulfonyl)benzamide
CAS 870141-47-2C20H24N2O4S
N-(4-Chlorophenyl)-4-methyl-3-(piperidine-1-sulfonyl)benzamide chemical structure, C19H21ClN2O3S, CAS 870260-08-5
N-(4-Chlorophenyl)-4-methyl-3-(piperidine-1-sulfonyl)benzamide
CAS 870260-08-5C19H21ClN2O3S
N-[2-(Difluoromethoxy)phenyl]-3-piperidin-1-ylsulfonylbenzamide chemical structure, C19H20F2N2O4S, CAS 887198-82-5
N-[2-(Difluoromethoxy)phenyl]-3-piperidin-1-ylsulfonylbenzamide
CAS 887198-82-5C19H20F2N2O4S
N-(4-Bromophenyl)-4-chloro-3-(piperidine-1-sulfonyl)benzamide chemical structure, C18H18BrClN2O3S, CAS 5725-34-8
N-(4-Bromophenyl)-4-chloro-3-(piperidine-1-sulfonyl)benzamide
CAS 5725-34-8C18H18BrClN2O3S
N-(3-Methoxyphenyl)-3-(piperidin-1-ylsulfonyl)benzamide chemical structure, C19H22N2O4S, CAS 1003728-78-6
N-(3-Methoxyphenyl)-3-(piperidin-1-ylsulfonyl)benzamide
CAS 1003728-78-6C19H22N2O4S
N-(4-Nitrophenyl)-3-piperidin-1-ylsulfonylbenzamide chemical structure, C18H19N3O5S, CAS 300670-47-7
N-(4-Nitrophenyl)-3-piperidin-1-ylsulfonylbenzamide
CAS 300670-47-7C18H19N3O5S