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Murcko scaffold

3-(Morpholine-4-sulfonyl)-N-phenylbenzamide scaffold

72 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
72
With full pages
11
Scaffold SMILES

O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCOCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(Morpholine-4-sulfonyl)-N-phenylbenzamide page
Murcko scaffold O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCOCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

3-(Morpholine-4-sulfonyl)-N-phenylbenzamide chemical structure, C17H18N2O4S, CAS 420832-30-0
3-(Morpholine-4-sulfonyl)-N-phenylbenzamide
CAS 420832-30-0C17H18N2O4S
4-Bromo-N-(2-fluorophenyl)-3-morpholin-4-ylsulfonylbenzamide chemical structure, C17H16BrFN2O4S, CAS 667901-80-6
4-Bromo-N-(2-fluorophenyl)-3-morpholin-4-ylsulfonylbenzamide
CAS 667901-80-6C17H16BrFN2O4S
3-(Morpholinosulfonyl)-N-(m-tolyl)benzamide chemical structure, C18H20N2O4S, CAS 300384-50-3
3-(Morpholinosulfonyl)-N-(m-tolyl)benzamide
CAS 300384-50-3C18H20N2O4S
4-Bromo-N-(2-hydroxyphenyl)-3-(morpholin-4-ylsulfonyl)benzamide chemical structure, C17H17BrN2O5S, CAS 312274-99-0
4-Bromo-N-(2-hydroxyphenyl)-3-(morpholin-4-ylsulfonyl)benzamide
CAS 312274-99-0C17H17BrN2O5S
4-Chloro-N-(4-fluorophenyl)-3-(4-morpholinylsulfonyl)benzamide chemical structure, C17H16ClFN2O4S, CAS 311800-19-8
4-Chloro-N-(4-fluorophenyl)-3-(4-morpholinylsulfonyl)benzamide
CAS 311800-19-8C17H16ClFN2O4S
2-Chloro-N-(4-iodophenyl)-5-morpholin-4-ylsulfonylbenzamide chemical structure, C17H16ClIN2O4S, CAS 313259-04-0
2-Chloro-N-(4-iodophenyl)-5-morpholin-4-ylsulfonylbenzamide
CAS 313259-04-0C17H16ClIN2O4S
4-Chloro-N-(4-iodophenyl)-3-(morpholinosulfonyl)benzamide chemical structure, C17H16ClIN2O4S, CAS 313259-07-3
4-Chloro-N-(4-iodophenyl)-3-(morpholinosulfonyl)benzamide
CAS 313259-07-3C17H16ClIN2O4S
N-(2-Methoxy-phenyl)-3-(morpholine-4-sulfonyl)-benzamide chemical structure, C18H20N2O5S, CAS 312759-07-2
N-(2-Methoxy-phenyl)-3-(morpholine-4-sulfonyl)-benzamide
CAS 312759-07-2C18H20N2O5S
4-[[[3-(4-Morpholinylsulfonyl)phenyl]-oxomethyl]amino]benzoic acid ethyl ester chemical structure, C20H22N2O6S, CAS 313659-11-9
4-[[[3-(4-Morpholinylsulfonyl)phenyl]-oxomethyl]amino]benzoic acid ethyl ester
CAS 313659-11-9C20H22N2O6S
N-(3-Acetyl-phenyl)-3-(morpholine-4-sulfonyl)-benzamide chemical structure, C19H20N2O5S, CAS 313659-13-1
N-(3-Acetyl-phenyl)-3-(morpholine-4-sulfonyl)-benzamide
CAS 313659-13-1C19H20N2O5S
N-(4-Acetylphenyl)-3-morpholin-4-ylsulfonylbenzamide chemical structure, C19H20N2O5S, CAS 313659-19-7
N-(4-Acetylphenyl)-3-morpholin-4-ylsulfonylbenzamide
CAS 313659-19-7C19H20N2O5S
4-Chloro-N-(2-hydroxyphenyl)-3-(4-morpholinylsulfonyl)benzamide chemical structure, C17H17ClN2O5S, CAS 361987-69-1
4-Chloro-N-(2-hydroxyphenyl)-3-(4-morpholinylsulfonyl)benzamide
CAS 361987-69-1C17H17ClN2O5S
N-(4-Methoxy-phenyl)-3-(morpholine-4-sulfonyl)-benzamide chemical structure, C18H20N2O5S, CAS 300670-41-1
N-(4-Methoxy-phenyl)-3-(morpholine-4-sulfonyl)-benzamide
CAS 300670-41-1C18H20N2O5S
3-(Morpholinosulfonyl)-N-(p-tolyl)benzamide chemical structure, C18H20N2O4S, CAS 352638-34-7
3-(Morpholinosulfonyl)-N-(p-tolyl)benzamide
CAS 352638-34-7C18H20N2O4S
2-Chloro-N-(2-methyl-5-nitrophenyl)-5-(4-morpholinylsulfonyl)benzamide chemical structure, C18H18ClN3O6S, CAS 313238-52-7
2-Chloro-N-(2-methyl-5-nitrophenyl)-5-(4-morpholinylsulfonyl)benzamide
CAS 313238-52-7C18H18ClN3O6S
N-(3-Chlorophenyl)-3-morpholin-4-ylsulfonylbenzamide chemical structure, C17H17ClN2O4S, CAS 412937-83-8
N-(3-Chlorophenyl)-3-morpholin-4-ylsulfonylbenzamide
CAS 412937-83-8C17H17ClN2O4S
N-(2-Methyl-5-nitrophenyl)-3-morpholin-4-ylsulfonylbenzamide chemical structure, C18H19N3O6S, CAS 301656-46-2
N-(2-Methyl-5-nitrophenyl)-3-morpholin-4-ylsulfonylbenzamide
CAS 301656-46-2C18H19N3O6S
3,4-Dichloro-N-(4-methoxyphenyl)-5-(4-morpholinylsulfonyl)benzamide chemical structure, C18H18Cl2N2O5S, CAS 445226-62-0
3,4-Dichloro-N-(4-methoxyphenyl)-5-(4-morpholinylsulfonyl)benzamide
CAS 445226-62-0C18H18Cl2N2O5S
N-(3-Chlorophenyl)-4-fluoro-3-morpholin-4-ylsulfonylbenzamide chemical structure, C17H16ClFN2O4S, CAS 352672-87-8
N-(3-Chlorophenyl)-4-fluoro-3-morpholin-4-ylsulfonylbenzamide
CAS 352672-87-8C17H16ClFN2O4S
2-Methyl-5-morpholin-4-ylsulfonyl-N-phenylbenzamide chemical structure, C18H20N2O4S, CAS 353467-68-2
2-Methyl-5-morpholin-4-ylsulfonyl-N-phenylbenzamide
CAS 353467-68-2C18H20N2O4S
Ethyl 4-{[2-hydroxy-5-(4-morpholinylsulfonyl)benzoyl]amino}benzoate chemical structure, C20H22N2O7S, CAS 615282-57-0
Ethyl 4-{[2-hydroxy-5-(4-morpholinylsulfonyl)benzoyl]amino}benzoate
CAS 615282-57-0C20H22N2O7S
N-[3,5-Bis(trifluoromethyl)phenyl]-2-methoxy-5-morpholin-4-ylsulfonylbenzamide chemical structure, C20H18F6N2O5S, CAS 690249-68-4
N-[3,5-Bis(trifluoromethyl)phenyl]-2-methoxy-5-morpholin-4-ylsulfonylbenzamide
CAS 690249-68-4C20H18F6N2O5S
N-[4-(Difluoromethylsulfonyl)phenyl]-2-methoxy-5-morpholin-4-ylsulfonylbenzamide chemical structure, C19H20F2N2O7S2, CAS 838816-59-4
N-[4-(Difluoromethylsulfonyl)phenyl]-2-methoxy-5-morpholin-4-ylsulfonylbenzamide
CAS 838816-59-4C19H20F2N2O7S2
4-Chloro-N-(2-fluorophenyl)-3-morpholin-4-ylsulfonylbenzamide chemical structure, C17H16ClFN2O4S, CAS 701931-27-3
4-Chloro-N-(2-fluorophenyl)-3-morpholin-4-ylsulfonylbenzamide
CAS 701931-27-3C17H16ClFN2O4S