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Murcko scaffold

Ring system with 3 rings and 22 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
24
With full pages
6
Scaffold SMILES

O=c1ccn(Cc2ccccc2)cc1OCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(Cc2ccccc2)cc1OCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

1-Benzyl-3-(benzyloxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H19NO2, CAS 127234-68-8
1-Benzyl-3-(benzyloxy)-2-methyl-4(1H)-pyridinone
CAS 127234-68-8C20H19NO2
3-((2,6-Dichlorobenzyl)oxy)-2-methyl-1-(4-methylbenzyl)-4(1H)-pyridinone chemical structure, C21H19Cl2NO2, CAS 338956-78-8
3-((2,6-Dichlorobenzyl)oxy)-2-methyl-1-(4-methylbenzyl)-4(1H)-pyridinone
CAS 338956-78-8C21H19Cl2NO2
3-((2-Chloro-6-fluorobenzyl)oxy)-1-(4-fluorobenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C20H16ClF2NO2, CAS 303144-63-0
3-((2-Chloro-6-fluorobenzyl)oxy)-1-(4-fluorobenzyl)-2-methyl-4(1H)-pyridinone
CAS 303144-63-0C20H16ClF2NO2
3-[(2-Chloro-6-fluorobenzyl)oxy]-2-methyl-1-(4-methylbenzyl)-4(1H)-pyridinone chemical structure, C21H19ClFNO2, CAS 303144-69-6
3-[(2-Chloro-6-fluorobenzyl)oxy]-2-methyl-1-(4-methylbenzyl)-4(1H)-pyridinone
CAS 303144-69-6C21H19ClFNO2
1-(4-Chlorobenzyl)-3-((2-chloro-6-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H16Cl2FNO2, CAS 303144-70-9
1-(4-Chlorobenzyl)-3-((2-chloro-6-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 303144-70-9C20H16Cl2FNO2
3-[(2-Chloro-6-fluorophenyl)methoxy]-2-methyl-1-[(4-nitrophenyl)methyl]pyridin-4-one chemical structure, C20H16ClFN2O4, CAS 303144-71-0
3-[(2-Chloro-6-fluorophenyl)methoxy]-2-methyl-1-[(4-nitrophenyl)methyl]pyridin-4-one
CAS 303144-71-0C20H16ClFN2O4
3-((2-Chloro-6-fluorobenzyl)oxy)-1-(2,4-dichlorobenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C20H15Cl3FNO2, CAS 303144-72-1
3-((2-Chloro-6-fluorobenzyl)oxy)-1-(2,4-dichlorobenzyl)-2-methyl-4(1H)-pyridinone
CAS 303144-72-1C20H15Cl3FNO2
1-(2-Chloro-6-fluorobenzyl)-3-((2-chloro-6-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H15Cl2F2NO2, CAS 303144-73-2
1-(2-Chloro-6-fluorobenzyl)-3-((2-chloro-6-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 303144-73-2C20H15Cl2F2NO2
1-Benzyl-3-((2-chloro-6-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H17ClFNO2, CAS 303144-74-3
1-Benzyl-3-((2-chloro-6-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 303144-74-3C20H17ClFNO2
1-(4-Chlorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H16Cl3NO2, CAS 338965-43-8
1-(4-Chlorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 338965-43-8C20H16Cl3NO2
3-(Benzyloxy)-1-(4-fluorobenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C20H18FNO2, CAS 338965-56-3
3-(Benzyloxy)-1-(4-fluorobenzyl)-2-methyl-4(1H)-pyridinone
CAS 338965-56-3C20H18FNO2
3-(Benzyloxy)-1-(4-chlorobenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C20H18ClNO2, CAS 338965-55-2
3-(Benzyloxy)-1-(4-chlorobenzyl)-2-methyl-4(1H)-pyridinone
CAS 338965-55-2C20H18ClNO2
1-(2-Chloro-6-fluorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H15Cl3FNO2, CAS 338965-33-6
1-(2-Chloro-6-fluorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 338965-33-6C20H15Cl3FNO2
3-((2,6-Dichlorobenzyl)oxy)-1-(4-fluorobenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C20H16Cl2FNO2, CAS 338965-40-5
3-((2,6-Dichlorobenzyl)oxy)-1-(4-fluorobenzyl)-2-methyl-4(1H)-pyridinone
CAS 338965-40-5C20H16Cl2FNO2
3-((2,6-Dichlorobenzyl)oxy)-1-(4-methoxybenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C21H19Cl2NO3, CAS 338965-53-0
3-((2,6-Dichlorobenzyl)oxy)-1-(4-methoxybenzyl)-2-methyl-4(1H)-pyridinone
CAS 338965-53-0C21H19Cl2NO3
3-(Benzyloxy)-1-(3,4-dichlorobenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C20H17Cl2NO2, CAS 338965-60-9
3-(Benzyloxy)-1-(3,4-dichlorobenzyl)-2-methyl-4(1H)-pyridinone
CAS 338965-60-9C20H17Cl2NO2
1-Benzyl-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H17Cl2NO2, CAS 338965-18-7
1-Benzyl-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 338965-18-7C20H17Cl2NO2
3-(Benzyloxy)-2-methyl-1-(4-methylbenzyl)-4(1H)-pyridinone chemical structure, C21H21NO2, CAS 338965-52-9
3-(Benzyloxy)-2-methyl-1-(4-methylbenzyl)-4(1H)-pyridinone
CAS 338965-52-9C21H21NO2
3-(Benzyloxy)-1-(2-chloro-6-fluorobenzyl)-2-methyl-4(1H)-pyridinone chemical structure, C20H17ClFNO2, CAS 338965-48-3
3-(Benzyloxy)-1-(2-chloro-6-fluorobenzyl)-2-methyl-4(1H)-pyridinone
CAS 338965-48-3C20H17ClFNO2
1-Benzyl-5-(benzyloxy)-4-oxo-1,4-dihydropyridine-2-carbaldehyde chemical structure, C20H17NO3, CAS 583887-01-8
1-Benzyl-5-(benzyloxy)-4-oxo-1,4-dihydropyridine-2-carbaldehyde
CAS 583887-01-8C20H17NO3
1-(3,4-Dichlorobenzyl)-3-((4-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H16Cl2FNO2, CAS 338965-61-0
1-(3,4-Dichlorobenzyl)-3-((4-fluorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 338965-61-0C20H16Cl2FNO2
1-(3,4-Dichlorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone chemical structure, C20H15Cl4NO2, CAS 338965-46-1
1-(3,4-Dichlorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methyl-4(1H)-pyridinone
CAS 338965-46-1C20H15Cl4NO2
4(1H)-Pyridinone, 2-(aminomethyl)-5-(phenylmethoxy)-1-(phenylmethyl)- chemical structure, C20H20N2O2, CAS 112334-26-6
4(1H)-Pyridinone, 2-(aminomethyl)-5-(phenylmethoxy)-1-(phenylmethyl)-
CAS 112334-26-6C20H20N2O2
1-Benzyl-3-(benzyloxy)-5-iodo-2-methyl-4(1H)-pyridinone chemical structure, C20H18INO2, CAS 1221792-03-5
1-Benzyl-3-(benzyloxy)-5-iodo-2-methyl-4(1H)-pyridinone
CAS 1221792-03-5C20H18INO2