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Murcko scaffold

Ring system with 2 rings and 12 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
11
With full pages
6
Scaffold SMILES

S=C1NC=CC(c2cccs2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C1NC=CC(c2cccs2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Ethyl 4-methyl-2-sulfanyl-6-(thiophen-2-yl)-1,6-dihydropyrimidine-5-carboxylate chemical structure, C12H14N2O2S2, CAS 302822-05-5
Ethyl 4-methyl-2-sulfanyl-6-(thiophen-2-yl)-1,6-dihydropyrimidine-5-carboxylate
CAS 302822-05-5C12H14N2O2S2
Methyl 6-methyl-4-(thiophen-2-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C11H12N2O2S2, CAS 302822-24-8
Methyl 6-methyl-4-(thiophen-2-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 302822-24-8C11H12N2O2S2
Methyl 4-methyl-6-(3-methylthiophen-2-yl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate chemical structure, C12H14N2O2S2, CAS 372496-39-4
Methyl 4-methyl-6-(3-methylthiophen-2-yl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate
CAS 372496-39-4C12H14N2O2S2
Allyl 6-methyl-4-(2-thienyl)-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C13H14N2O2S2, CAS 432010-97-4
Allyl 6-methyl-4-(2-thienyl)-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS 432010-97-4C13H14N2O2S2
N,6-dimethyl-2-sulfanylidene-4-thiophen-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C11H13N3OS2, CAS 433255-90-4
N,6-dimethyl-2-sulfanylidene-4-thiophen-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 433255-90-4C11H13N3OS2
N,N,6-trimethyl-2-sulfanylidene-4-thiophen-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxamide chemical structure, C12H15N3OS2, CAS 434296-96-5
N,N,6-trimethyl-2-sulfanylidene-4-thiophen-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxamide
CAS 434296-96-5C12H15N3OS2
Ethyl 6-methyl-4-(5-methylthiophen-2-yl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C13H16N2O2S2, CAS 486993-61-7
Ethyl 6-methyl-4-(5-methylthiophen-2-yl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate
CAS 486993-61-7C13H16N2O2S2
Ethyl 3,4-dimethyl-2-sulfanylidene-6-thiophen-2-yl-1,6-dihydropyrimidine-5-carboxylate chemical structure, C13H16N2O2S2, CAS 537002-67-8
Ethyl 3,4-dimethyl-2-sulfanylidene-6-thiophen-2-yl-1,6-dihydropyrimidine-5-carboxylate
CAS 537002-67-8C13H16N2O2S2
Ethyl 1-ethyl-6-methyl-2-sulfanylidene-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H18N2O2S2, CAS 743444-84-0
Ethyl 1-ethyl-6-methyl-2-sulfanylidene-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 743444-84-0C14H18N2O2S2
Methyl 3,4-dimethyl-2-sulfanylidene-6-thiophen-2-yl-1,6-dihydropyrimidine-5-carboxylate chemical structure, C12H14N2O2S2, CAS 537002-66-7
Methyl 3,4-dimethyl-2-sulfanylidene-6-thiophen-2-yl-1,6-dihydropyrimidine-5-carboxylate
CAS 537002-66-7C12H14N2O2S2
Isopropyl 6-methyl-4-(thiophen-2-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C13H16N2O2S2, CAS 518982-84-8
Isopropyl 6-methyl-4-(thiophen-2-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 518982-84-8C13H16N2O2S2