CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 16 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
7
With full pages
3
Scaffold SMILES

O=c1[nH]c2c(s1)C(c1ccccc1)CCS2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2c(s1)C(c1ccccc1)CCS2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Ethyl 2-oxo-7-phenyl-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d][1,3]thiazole-6-carboxylate chemical structure, C15H15NO3S2, CAS 51746-64-6
Ethyl 2-oxo-7-phenyl-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d][1,3]thiazole-6-carboxylate
CAS 51746-64-6C15H15NO3S2
Dimethyl 7-(3-nitrophenyl)-2-oxo-3,5,6,7-tetrahydrothiopyrano[2,3-d][1,3]thiazole-5,6-dicarboxylate chemical structure, C16H14N2O7S2, CAS 1005040-03-8
Dimethyl 7-(3-nitrophenyl)-2-oxo-3,5,6,7-tetrahydrothiopyrano[2,3-d][1,3]thiazole-5,6-dicarboxylate
CAS 1005040-03-8C16H14N2O7S2
7-(4-Methoxyphenyl)-2-oxo-3,5,6,7-tetrahydrothiopyrano[2,3-d][1,3]thiazole-6-carboxamide chemical structure, C14H14N2O3S2, CAS 488800-90-4
7-(4-Methoxyphenyl)-2-oxo-3,5,6,7-tetrahydrothiopyrano[2,3-d][1,3]thiazole-6-carboxamide
CAS 488800-90-4C14H14N2O3S2
7-(4-Methoxyphenyl)-2-oxo-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d][1,3]thiazole-6-carbaldehyde chemical structure, C14H13NO3S2, CAS 494830-80-7
7-(4-Methoxyphenyl)-2-oxo-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d][1,3]thiazole-6-carbaldehyde
CAS 494830-80-7C14H13NO3S2
Diethyl 7-(2-hydroxy-5-nitrophenyl)-2-oxo-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d]thiazole-5,6-dicarboxylate chemical structure, C18H18N2O8S2, CAS 1005089-81-5
Diethyl 7-(2-hydroxy-5-nitrophenyl)-2-oxo-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d]thiazole-5,6-dicarboxylate
CAS 1005089-81-5C18H18N2O8S2
5,6-Diethyl 7-(4-chlorophenyl)-2-oxo-2H,3H,5H,6H,7H-thiopyrano[2,3-d][1,3]thiazole-5,6-dicarboxylate chemical structure, C18H18ClNO5S2, CAS 1005116-31-3
5,6-Diethyl 7-(4-chlorophenyl)-2-oxo-2H,3H,5H,6H,7H-thiopyrano[2,3-d][1,3]thiazole-5,6-dicarboxylate
CAS 1005116-31-3C18H18ClNO5S2
7-[4-(Difluoromethoxy)-3-methoxyphenyl]-2-oxo-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d][1,3]thiazole-6-carbaldehyde chemical structure, C15H13F2NO4S2, CAS 879581-30-3
7-[4-(Difluoromethoxy)-3-methoxyphenyl]-2-oxo-3,5,6,7-tetrahydro-2H-thiopyrano[2,3-d][1,3]thiazole-6-carbaldehyde
CAS 879581-30-3C15H13F2NO4S2