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Murcko scaffold

Pyrimido(5,4-d)pyrimidine scaffold

36 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 10
Chemicals: 36
With full pages: 4

Scaffold SMILES

c1ncc2ncncc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Pyrimido(5,4-d)pyrimidine page

Murcko scaffold c1ncc2ncncc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

Tetrachloropyrimido[5,4-d]pyrimidine chemical structure, C6Cl4N4, CAS 32980-71-5

Tetrachloropyrimido[5,4-d]pyrimidine

CAS 32980-71-5C₆Cl₄N₄

Awd 627 chemical structure, C18H32N8O4, CAS 16908-49-9

CAS 16908-49-9C₁₈H₃₂N₈O₄

Pyrimido(5,4-d)pyrimidine, ethanol deriv. chemical structure, C24H44N8O4, CAS 54093-30-0

Pyrimido(5,4-d)pyrimidine, ethanol deriv.

CAS 54093-30-0C₂₄H₄₄N₈O₄

2,4,8-Trichloropyrimido[5,4-d][1,3]diazine chemical structure, C6HCl3N4, CAS 77776-68-2

2,4,8-Trichloropyrimido[5,4-d][1,3]diazine

CAS 77776-68-2C₆HCl₃N₄

6-Methylpyrimido[5,4-d]pyrimidine-2,4-diamine chemical structure, C7H8N6, CAS 7496-37-9

6-Methylpyrimido[5,4-d]pyrimidine-2,4-diamine

CAS 7496-37-9C₇H₈N₆

2-[[4,8-Diamino-2-[bis(2-hydroxyethyl)amino]pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol chemical structure, C14H24N8O4, CAS 13120-27-9

2-[[4,8-Diamino-2-[bis(2-hydroxyethyl)amino]pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol

CAS 13120-27-9C₁₄H₂₄N₈O₄

2-Chloro-N~4~,N~8~-dimethylpyrimido[5,4-d]pyrimidine-4,8-diamine chemical structure, C8H9ClN6, CAS 89981-54-4

2-Chloro-N~4~,N~8~-dimethylpyrimido[5,4-d]pyrimidine-4,8-diamine

CAS 89981-54-4C₈H₉ClN₆

2-[[4-[Bis(2-hydroxyethyl)amino]-2,6-dichloropyrimido[5,4-d]pyrimidin-8-yl]-(2-hydroxyethyl)amino]ethanol chemical structure, C14H20Cl2N6O4, CAS 68030-10-4

2-[[4-[Bis(2-hydroxyethyl)amino]-2,6-dichloropyrimido[5,4-d]pyrimidin-8-yl]-(2-hydroxyethyl)amino]ethanol

CAS 68030-10-4C₁₄H₂₀Cl₂N₆O₄

2,6-Dichloropyrimido[5,4-d]pyrimidine-4,8-diamine chemical structure, C6H4Cl2N6, CAS 89281-25-4

2,6-Dichloropyrimido[5,4-d]pyrimidine-4,8-diamine

CAS 89281-25-4C₆H₄Cl₂N₆

2-[[2,6-Dichloro-4-(2-hydroxyethylamino)pyrimido[5,4-d]pyrimidin-8-yl]amino]ethanol chemical structure, C10H12Cl2N6O2, CAS 68030-09-1

2-[[2,6-Dichloro-4-(2-hydroxyethylamino)pyrimido[5,4-d]pyrimidin-8-yl]amino]ethanol

CAS 68030-09-1C₁₀H₁₂Cl₂N₆O₂

2-Chloropyrimido[5,4-d]pyrimidine-4,8-diamine chemical structure, C6H5ClN6, CAS 98138-79-5

2-Chloropyrimido[5,4-d]pyrimidine-4,8-diamine

CAS 98138-79-5C₆H₅ClN₆

2-[[8-[Bis(2-hydroxyethyl)amino]-2,6-bis(diethylamino)pyrimido[5,4-d]pyrimidin-4-yl]-(2-hydroxyethyl)amino]ethanol chemical structure, C22H40N8O4, CAS 16908-41-1

2-[[8-[Bis(2-hydroxyethyl)amino]-2,6-bis(diethylamino)pyrimido[5,4-d]pyrimidin-4-yl]-(2-hydroxyethyl)amino]ethanol

CAS 16908-41-1C₂₂H₄₀N₈O₄

2-[[2,4,6-Tris(2-hydroxyethylamino)pyrimido[5,4-d]pyrimidin-8-yl]amino]ethanol chemical structure, C14H24N8O4, CAS 16888-03-2

2-[[2,4,6-Tris(2-hydroxyethylamino)pyrimido[5,4-d]pyrimidin-8-yl]amino]ethanol

CAS 16888-03-2C₁₄H₂₄N₈O₄

N~2~,N~4~,N~8~-Trimethylpyrimido[5,4-d]pyrimidine-2,4,8-triamine chemical structure, C9H13N7, CAS 16888-00-9

N~2~,N~4~,N~8~-Trimethylpyrimido[5,4-d]pyrimidine-2,4,8-triamine

CAS 16888-00-9C₉H₁₃N₇

N~2~,N~4~,N~6~,N~8~-Tetramethylpyrimido[5,4-d]pyrimidine-2,4,6,8-tetramine chemical structure, C10H16N8, CAS 16888-05-4

N~2~,N~4~,N~6~,N~8~-Tetramethylpyrimido[5,4-d]pyrimidine-2,4,6,8-tetramine

CAS 16888-05-4C₁₀H₁₆N₈

N~2~,N~2~,N~4~,N~4~,N~6~,N~6~,N~8~,N~8~-Octamethylpyrimido[5,4-d]pyrimidine-2,4,6,8-tetramine chemical structure, C14H24N8, CAS 63023-19-8

N~2~,N~2~,N~4~,N~4~,N~6~,N~6~,N~8~,N~8~-Octamethylpyrimido[5,4-d]pyrimidine-2,4,6,8-tetramine

CAS 63023-19-8C₁₄H₂₄N₈

Pyrimido[5,4-d]pyrimidine-4,8-diamine chemical structure, C6H6N6, CAS 23149-81-7

Pyrimido[5,4-d]pyrimidine-4,8-diamine

CAS 23149-81-7C₆H₆N₆

4-N,4-N,8-N,8-N-tetramethylpyrimido[5,4-d]pyrimidine-4,8-diamine chemical structure, C10H14N6, CAS 90924-81-5

4-N,4-N,8-N,8-N-tetramethylpyrimido[5,4-d]pyrimidine-4,8-diamine

CAS 90924-81-5C₁₀H₁₄N₆

2-[[2-[Bis(2-hydroxyethyl)amino]-4,8-bis(diethylamino)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol chemical structure, C22H40N8O4, CAS 16908-48-8

2-[[2-[Bis(2-hydroxyethyl)amino]-4,8-bis(diethylamino)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol

CAS 16908-48-8C₂₂H₄₀N₈O₄

2-[[2-[Bis(2-hydroxyethyl)amino]-4,8-bis(dimethylamino)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol chemical structure, C18H32N8O4, CAS 29491-68-7

2-[[2-[Bis(2-hydroxyethyl)amino]-4,8-bis(dimethylamino)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol

CAS 29491-68-7C₁₈H₃₂N₈O₄

2,8-Dichloropyrimido[5,4-D]pyrimidine chemical structure, C6H2Cl2N4, CAS 189747-34-0

2,8-Dichloropyrimido[5,4-D]pyrimidine

CAS 189747-34-0C₆H₂Cl₂N₄

2,8-Dichloro-N,N-diethylpyrimido[5,4-d]pyrimidin-4-amine chemical structure, C10H11Cl2N5, CAS 101850-43-5

2,8-Dichloro-N,N-diethylpyrimido[5,4-d]pyrimidin-4-amine

CAS 101850-43-5C₁₀H₁₁Cl₂N₅

8-Chloro-2-(methylthio)pyrimido[5,4-d]pyrimidine chemical structure, C7H5ClN4S, CAS 176637-10-8

8-Chloro-2-(methylthio)pyrimido[5,4-d]pyrimidine

CAS 176637-10-8C₇H₅ClN₄S

2-((4,8-Bis(bis(2-methylpropyl)amino)-6-((2-hydroxyethyl)amino)pyrimido(5,4-d)(1,3)diazin-2-yl)amino)ethan-1-ol chemical structure, C26H48N8O2, CAS 949467-71-4

2-((4,8-Bis(bis(2-methylpropyl)amino)-6-((2-hydroxyethyl)amino)pyrimido(5,4-d)(1,3)diazin-2-yl)amino)ethan-1-ol

CAS 949467-71-4C₂₆H₄₈N₈O₂