CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 11 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
14
With full pages
3
Scaffold SMILES

c1nc(N2CCNCC2)no1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(N2CCNCC2)no1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1,1-Dimethylethyl 4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]piperazine-1-carboxylate chemical structure, C12H19ClN4O3, CAS 650579-72-9
1,1-Dimethylethyl 4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]piperazine-1-carboxylate
CAS 650579-72-9C12H19ClN4O3
5-Isopropyl-3-(piperazin-1-yl)-1,2,4-oxadiazole chemical structure, C9H16N4O, CAS 1351562-76-9
5-Isopropyl-3-(piperazin-1-yl)-1,2,4-oxadiazole
CAS 1351562-76-9C9H16N4O
1-(5-Methyl-1,2,4-oxadiazol-3-yl)piperazine chemical structure, C7H12N4O, CAS 1019637-82-1
1-(5-Methyl-1,2,4-oxadiazol-3-yl)piperazine
CAS 1019637-82-1C7H12N4O
tert-Butyl 4-(5-methyl-1,2,4-oxadiazol-3-yl)piperazine-1-carboxylate chemical structure, C12H20N4O3, CAS 1019637-81-0
tert-Butyl 4-(5-methyl-1,2,4-oxadiazol-3-yl)piperazine-1-carboxylate
CAS 1019637-81-0C12H20N4O3
1-(5-Methyl-1,2,4-oxadiazol-3-yl)piperazine hydrochloride chemical structure, C7H13ClN4O, CAS 1440955-11-2
1-(5-Methyl-1,2,4-oxadiazol-3-yl)piperazine hydrochloride
CAS 1440955-11-2C7H13ClN4O
1-Amino-1-[3-(4-methylpiperazin-1-yl)-1,2,4-oxadiazol-5-yl]propan-2-ol chemical structure, C10H19N5O2, CAS 1712102-15-2
1-Amino-1-[3-(4-methylpiperazin-1-yl)-1,2,4-oxadiazol-5-yl]propan-2-ol
CAS 1712102-15-2C10H19N5O2
Starbld0041337 chemical structure, C14H23N7O6
Starbld0041337
C14H23N7O6
PD1-Pdl1-IN 1 chemical structure, C14H23N7O6, CAS 2005454-12-4
PD1-Pdl1-IN 1
CAS 2005454-12-4C14H23N7O6
(2S)-2-[[(1S)-3-Amino-3-oxo-1-(3-piperazin-1-yl-1,2,4-oxadiazol-5-yl)propyl]carbamoylamino]-3-hydroxy-butanoic acid chemical structure, C14H23N7O6
(2S)-2-[[(1S)-3-Amino-3-oxo-1-(3-piperazin-1-yl-1,2,4-oxadiazol-5-yl)propyl]carbamoylamino]-3-hydroxy-butanoic acid
C14H23N7O6
(1R)-1-{3-[4-(2-Methylpropyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl}pentan-1-amine chemical structure, C15H29N5O, CAS 2171259-09-7
(1R)-1-{3-[4-(2-Methylpropyl)piperazin-1-yl]-1,2,4-oxadiazol-5-yl}pentan-1-amine
CAS 2171259-09-7C15H29N5O
3-[3-(4-Acetylpiperazin-1-yl)-1,2,4-oxadiazol-5-yl]-3-aminopropanamide chemical structure, C11H18N6O3, CAS 2172120-98-6
3-[3-(4-Acetylpiperazin-1-yl)-1,2,4-oxadiazol-5-yl]-3-aminopropanamide
CAS 2172120-98-6C11H18N6O3
Ethyl 4-{5-[(1S)-1-amino-2-methyl-2-sulfanylpropyl]-1,2,4-oxadiazol-3-yl}piperazine-1-carboxylate chemical structure, C13H23N5O3S, CAS 2171141-30-1
Ethyl 4-{5-[(1S)-1-amino-2-methyl-2-sulfanylpropyl]-1,2,4-oxadiazol-3-yl}piperazine-1-carboxylate
CAS 2171141-30-1C13H23N5O3S
2-(4-{5-[(1R)-1-Amino-2-methylpropyl]-1,2,4-oxadiazol-3-yl}piperazin-1-yl)ethan-1-ol chemical structure, C12H23N5O2, CAS 2171266-05-8
2-(4-{5-[(1R)-1-Amino-2-methylpropyl]-1,2,4-oxadiazol-3-yl}piperazin-1-yl)ethan-1-ol
CAS 2171266-05-8C12H23N5O2
tert-Butyl 4-[5-(aminomethyl)-1,2,4-oxadiazol-3-yl]piperazine-1-carboxylate chemical structure, C12H21N5O3, CAS 2924095-16-7
tert-Butyl 4-[5-(aminomethyl)-1,2,4-oxadiazol-3-yl]piperazine-1-carboxylate
CAS 2924095-16-7C12H21N5O3