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Murcko scaffold

2,3-Piperazinedione scaffold

87 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
87
With full pages
7
Scaffold SMILES

O=C1NCCNC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Piperazinedione page
Murcko scaffold O=C1NCCNC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 87 chemicals

2,3-Piperazinedione chemical structure, C4H6N2O2, CAS 13092-86-9
2,3-Piperazinedione
CAS 13092-86-9C4H6N2O2
1-Ethyl-2,3-piperazinedione chemical structure, C6H10N2O2, CAS 59702-31-7
1-Ethyl-2,3-piperazinedione
CAS 59702-31-7C6H10N2O2
4-Ethyl-2,3-dioxopiperazinecarbonyl chloride chemical structure, C7H9ClN2O3, CAS 59703-00-3
4-Ethyl-2,3-dioxopiperazinecarbonyl chloride
CAS 59703-00-3C7H9ClN2O3
1-(2-(4-Ethyl-2,3-dioxo-1-piperaziny)ethyl)-3-methylurea chemical structure, C10H18N4O3, CAS 77439-64-6
1-(2-(4-Ethyl-2,3-dioxo-1-piperaziny)ethyl)-3-methylurea
CAS 77439-64-6C10H18N4O3
2,3-Piperazinedione, 1-butyl- chemical structure, C8H14N2O2, CAS 2385-28-6
2,3-Piperazinedione, 1-butyl-
CAS 2385-28-6C8H14N2O2
5-Methylpiperazine-2,3-dione chemical structure, C5H8N2O2, CAS 93561-56-9
5-Methylpiperazine-2,3-dione
CAS 93561-56-9C5H8N2O2
1,4-Diaminopiperazine-2,3-dione chemical structure, C4H8N4O2, CAS 59417-00-4
1,4-Diaminopiperazine-2,3-dione
CAS 59417-00-4C4H8N4O2
1,4-Dimethylpiperazine-2,3-dione chemical structure, C6H10N2O2, CAS 59417-06-0
1,4-Dimethylpiperazine-2,3-dione
CAS 59417-06-0C6H10N2O2
5,5,6,6-Tetramethyl-1,4-bis(prop-2-enoxy)piperazine-2,3-dione chemical structure, C14H22N2O4, CAS 286409-71-0
5,5,6,6-Tetramethyl-1,4-bis(prop-2-enoxy)piperazine-2,3-dione
CAS 286409-71-0C14H22N2O4
1,4-Dimethoxy-5,5,6-trimethylpiperazine-2,3-dione chemical structure, C9H16N2O4, CAS 286409-67-4
1,4-Dimethoxy-5,5,6-trimethylpiperazine-2,3-dione
CAS 286409-67-4C9H16N2O4
2,3-Piperazinedione, 1-methyl- chemical structure, C5H8N2O2, CAS 59702-29-3
2,3-Piperazinedione, 1-methyl-
CAS 59702-29-3C5H8N2O2
2,3-Piperazinedione, 1-propyl- chemical structure, C7H12N2O2, CAS 59702-32-8
2,3-Piperazinedione, 1-propyl-
CAS 59702-32-8C7H12N2O2
2,3-Piperazinedione, 1-octyl- chemical structure, C12H22N2O2, CAS 59702-37-3
2,3-Piperazinedione, 1-octyl-
CAS 59702-37-3C12H22N2O2
Urea, N-(2-chloroethyl)-N'-(4-(2,3-dioxo-4-ethyl-1-piperazinyl)butyl)-N-nitroso- chemical structure, C13H22ClN5O4, CAS 69000-73-3
Urea, N-(2-chloroethyl)-N'-(4-(2,3-dioxo-4-ethyl-1-piperazinyl)butyl)-N-nitroso-
CAS 69000-73-3C13H22ClN5O4
Urea, N-(2-chloroethyl)-N'-(6-(2,3-dioxo-4-ethyl-1-piperazinyl)hexyl)-N-nitroso- chemical structure, C15H26ClN5O4, CAS 69000-74-4
Urea, N-(2-chloroethyl)-N'-(6-(2,3-dioxo-4-ethyl-1-piperazinyl)hexyl)-N-nitroso-
CAS 69000-74-4C15H26ClN5O4
Urea, N-(2-chloroethyl)-N'-(2-(2,3-dioxo-4-methyl-1-piperazinyl)ethyl)-N-nitroso- chemical structure, C10H16ClN5O4, CAS 69000-76-6
Urea, N-(2-chloroethyl)-N'-(2-(2,3-dioxo-4-methyl-1-piperazinyl)ethyl)-N-nitroso-
CAS 69000-76-6C10H16ClN5O4
Urea, N-(2-chloroethyl)-N'-(2-(2,3-dioxo-4-ethyl-1-piperazinyl)ethyl)-N-nitroso- chemical structure, C11H18ClN5O4, CAS 69000-77-7
Urea, N-(2-chloroethyl)-N'-(2-(2,3-dioxo-4-ethyl-1-piperazinyl)ethyl)-N-nitroso-
CAS 69000-77-7C11H18ClN5O4
Urea, N-(2-chloroethyl)-N'-((2,3-dioxo-4-ethyl-1-piperazinyl)methyl)-N-nitroso- chemical structure, C10H16ClN5O4, CAS 69000-78-8
Urea, N-(2-chloroethyl)-N'-((2,3-dioxo-4-ethyl-1-piperazinyl)methyl)-N-nitroso-
CAS 69000-78-8C10H16ClN5O4
Urea, N-(2-chloroethyl)-N'-(2-(2,3-dioxo-4-octyl-1-piperazinyl)ethyl)-N-nitroso- chemical structure, C17H30ClN5O4, CAS 69000-79-9
Urea, N-(2-chloroethyl)-N'-(2-(2,3-dioxo-4-octyl-1-piperazinyl)ethyl)-N-nitroso-
CAS 69000-79-9C17H30ClN5O4
Urea, N-(2-chloroethyl)-N'-(2,3-dioxo-4-ethyl-1-piperazinyl)-N-nitroso- chemical structure, C9H14ClN5O4, CAS 69000-82-4
Urea, N-(2-chloroethyl)-N'-(2,3-dioxo-4-ethyl-1-piperazinyl)-N-nitroso-
CAS 69000-82-4C9H14ClN5O4
Urea, N-(2-chloroethyl)-N'-(3-(2,3-dioxo-4-octyl-1-piperazinyl)propyl)-N-nitroso- chemical structure, C18H32ClN5O4, CAS 69000-89-1
Urea, N-(2-chloroethyl)-N'-(3-(2,3-dioxo-4-octyl-1-piperazinyl)propyl)-N-nitroso-
CAS 69000-89-1C18H32ClN5O4
Urea, N-(2-chloroethyl)-N'-(3-(2,3-dioxo-4-methyl-1-piperazinyl)propyl)-N-nitroso- chemical structure, C11H18ClN5O4, CAS 69000-90-4
Urea, N-(2-chloroethyl)-N'-(3-(2,3-dioxo-4-methyl-1-piperazinyl)propyl)-N-nitroso-
CAS 69000-90-4C11H18ClN5O4
Urea, N-(2-chloroethyl)-N'-(3-(2,3-dioxo-4-propyl-1-piperazinyl)propyl)-N-nitroso- chemical structure, C13H22ClN5O4, CAS 69000-91-5
Urea, N-(2-chloroethyl)-N'-(3-(2,3-dioxo-4-propyl-1-piperazinyl)propyl)-N-nitroso-
CAS 69000-91-5C13H22ClN5O4
Urea, N'-(3-(4-butyl-2,3-dioxo-1-piperazinyl)propyl)-N-(2-chloroethyl)-N-nitroso- chemical structure, C14H24ClN5O4, CAS 69000-92-6
Urea, N'-(3-(4-butyl-2,3-dioxo-1-piperazinyl)propyl)-N-(2-chloroethyl)-N-nitroso-
CAS 69000-92-6C14H24ClN5O4