CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 19 atoms

15 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
15
With full pages
12
Scaffold SMILES

O=C(COC(=O)c1ccccc1)Nc1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1ccccc1)Nc1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

[2-[(3,5-Dichloropyridin-2-yl)amino]-2-oxoethyl] 2-hydroxybenzoate chemical structure, C14H10Cl2N2O4, CAS 723323-36-2
[2-[(3,5-Dichloropyridin-2-yl)amino]-2-oxoethyl] 2-hydroxybenzoate
CAS 723323-36-2C14H10Cl2N2O4
[2-[(3,5-Dichloropyridin-2-yl)amino]-2-oxoethyl] 4-hydroxybenzoate chemical structure, C14H10Cl2N2O4, CAS 473889-80-4
[2-[(3,5-Dichloropyridin-2-yl)amino]-2-oxoethyl] 4-hydroxybenzoate
CAS 473889-80-4C14H10Cl2N2O4
[2-[(3,5-Dichloro-6-methylpyridin-2-yl)amino]-2-oxoethyl] 4-(hydroxymethyl)benzoate chemical structure, C16H14Cl2N2O4, CAS 730972-40-4
[2-[(3,5-Dichloro-6-methylpyridin-2-yl)amino]-2-oxoethyl] 4-(hydroxymethyl)benzoate
CAS 730972-40-4C16H14Cl2N2O4
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 4-fluorobenzoate chemical structure, C14H10ClFN2O3, CAS 502440-86-0
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 4-fluorobenzoate
CAS 502440-86-0C14H10ClFN2O3
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 3-fluorobenzoate chemical structure, C14H10ClFN2O3, CAS 790707-65-2
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 3-fluorobenzoate
CAS 790707-65-2C14H10ClFN2O3
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 4-(carbamoylamino)benzoate chemical structure, C15H13ClN4O4, CAS 852028-57-0
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 4-(carbamoylamino)benzoate
CAS 852028-57-0C15H13ClN4O4
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 4-methoxybenzoate chemical structure, C15H13ClN2O4, CAS 852028-95-6
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 4-methoxybenzoate
CAS 852028-95-6C15H13ClN2O4
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 2,4-difluorobenzoate chemical structure, C14H9ClF2N2O3, CAS 852686-85-2
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 2,4-difluorobenzoate
CAS 852686-85-2C14H9ClF2N2O3
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 2-methoxybenzoate chemical structure, C15H13ClN2O4, CAS 793713-56-1
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 2-methoxybenzoate
CAS 793713-56-1C15H13ClN2O4
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 3-acetamidobenzoate chemical structure, C16H14ClN3O4, CAS 923858-84-8
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 3-acetamidobenzoate
CAS 923858-84-8C16H14ClN3O4
[1-[(5-Chloropyridin-2-yl)amino]-1-oxopropan-2-yl] 4-cyanobenzoate chemical structure, C16H12ClN3O3, CAS 852870-26-9
[1-[(5-Chloropyridin-2-yl)amino]-1-oxopropan-2-yl] 4-cyanobenzoate
CAS 852870-26-9C16H12ClN3O3
[2-[(3,5-Dichloro-4-methylpyridin-2-yl)amino]-2-oxoethyl] 2-methoxy-5-sulfamoylbenzoate chemical structure, C16H15Cl2N3O6S, CAS 853727-32-9
[2-[(3,5-Dichloro-4-methylpyridin-2-yl)amino]-2-oxoethyl] 2-methoxy-5-sulfamoylbenzoate
CAS 853727-32-9C16H15Cl2N3O6S
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 2,4-dihydroxybenzoate chemical structure, C14H11ClN2O5, CAS 1003251-14-6
[2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl] 2,4-dihydroxybenzoate
CAS 1003251-14-6C14H11ClN2O5
N-(5-Chloro-2-pyridinyl)-2-[(2-nitrobenzoyl)oxy]propanamide chemical structure, C15H12ClN3O5, CAS 926188-45-6
N-(5-Chloro-2-pyridinyl)-2-[(2-nitrobenzoyl)oxy]propanamide
CAS 926188-45-6C15H12ClN3O5
1-[(5-Chloropyridin-2-yl)amino]-1-oxopropan-2-yl 3-chlorobenzoate chemical structure, C15H12Cl2N2O3, CAS 1008265-59-5
1-[(5-Chloropyridin-2-yl)amino]-1-oxopropan-2-yl 3-chlorobenzoate
CAS 1008265-59-5C15H12Cl2N2O3