Murcko scaffold
Ring system with 2 rings and 10 atoms
36 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 36
- With full pages
- 1
Scaffold SMILES
C1CCC(C2CCCO2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 36 of 36 chemicals
1-(2-Tetrahydrofuranyl)cyclopentanol
CAS 676456-82-9C9H16O2
2-(Tetrahydrofuran-2-yl)cyclopentanamine
CAS 6094-52-6C9H17NO
Cyclonerodiol oxide
CAS 28834-16-4C15H28O3
1-(Oxolan-2-yl)cyclopentan-1-amine
CAS 1892965-59-1C9H17NO
2-Cyclopentyloxolane-2-carboxylic acid
CAS 1934636-28-8C10H16O3
2-(Chloromethyl)-2-cyclopentyloxolane
CAS 1935336-36-9C10H17ClO
2-(Bromomethyl)-2-cyclopentyloxolane
CAS 1936349-66-4C10H17BrO
1-(Oxolan-2-yl)cyclopentane-1-carboxylic acid
CAS 2137557-91-4C10H16O3
![[1-(Oxolan-2-yl)cyclopentyl]methanol chemical structure, C10H18O2, CAS 2160764-53-2](/s/ODBXZZNKZFKLNR-UHFFFAOYSA-N.svg)
[1-(Oxolan-2-yl)cyclopentyl]methanol
CAS 2160764-53-2C10H18O2
5-Cyclopentyl-2-(methoxymethyl)oxolane-3-carboxylic acid
CAS 2172597-94-1C12H20O4
![2-[1-(Chloromethyl)cyclopentyl]oxolane chemical structure, C10H17ClO, CAS 2138142-24-0](/s/OSEPHKOQXGNRIH-UHFFFAOYSA-N.svg)
2-[1-(Chloromethyl)cyclopentyl]oxolane
CAS 2138142-24-0C10H17ClO
![2-[1-(Bromomethyl)cyclopentyl]oxolane chemical structure, C10H17BrO, CAS 2138190-67-5](/s/VMHQLCOMEMUPKI-UHFFFAOYSA-N.svg)
2-[1-(Bromomethyl)cyclopentyl]oxolane
CAS 2138190-67-5C10H17BrO
![1-[1-(Oxolan-2-yl)cyclopentyl]methanamine chemical structure, C10H19NO, CAS 2138003-61-7](/s/GJQGSDBRDXBMGO-UHFFFAOYSA-N.svg)
1-[1-(Oxolan-2-yl)cyclopentyl]methanamine
CAS 2138003-61-7C10H19NO
2-Cyclopentyl-5-(2-methylbutan-2-yl)oxolane-3-carboxylic acid
CAS 2171833-00-2C15H26O3
2-Cyclopentyl-5-ethyloxolane-3-carboxylic acid
CAS 2171935-22-9C12H20O3
5-Cyclopentyl-2-(propan-2-yl)oxolane-3-carboxylic acid
CAS 2171935-33-2C13H22O3
2-Cyclopentyl-5-(propan-2-yl)oxolane-3-carboxylic acid
CAS 2171862-32-9C13H22O3
2-Cyclopentyl-5-(2-methylpropyl)oxolane-3-carboxylic acid
CAS 2172437-44-2C14H24O3
3-Methyl-1-(oxolan-2-yl)cyclopentane-1-carbaldehyde
CAS 2172535-14-5C11H18O2
2-Cyclopentyloxolane-2-carbaldehyde
CAS 2172546-92-6C10H16O2
2-Methyl-1-(oxolan-2-yl)cyclopentane-1-carbaldehyde
CAS 2172449-65-7C11H18O2
2-(2-Hydroxycyclopentyl)oxolane-2-carbaldehyde
CAS 2171842-36-5C10H16O3
5-Cyclopentyl-2-methyloxolane-3-carboxylic acid
CAS 2172575-72-1C11H18O3
5-Cyclopentyl-2-(trifluoromethyl)oxolane-3-carboxylic acid
CAS 2172075-94-2C11H15F3O3
- 5-Cyclopentyl-2-ethyloxolane-3-carboxylic acid2172553-09-0C12H20O3
- 5-Cyclopentyl-2-propyloxolane-3-carboxylic acid2172599-32-3C13H22O3
- 5-Cyclopentyl-2-(1-methoxyethyl)oxolane-3-carboxylic acid2172513-74-3C13H22O4
- 5-Butyl-2-cyclopentyloxolane-3-carboxylic acid2172491-75-5C14H24O3
- 2-Cyclopentyl-5-(ethoxymethyl)oxolane-3-carboxylic acid2172589-80-7C13H22O4
- 2-Cyclopentyl-5-(2-methoxyethyl)oxolane-3-carboxylic acid2172604-79-2C13H22O4
- 5-tert-Butyl-2-cyclopentyloxolane-3-carboxylic acid2172541-30-7C14H24O3
- 1-(Oxolan-2-yl)cyclopentane-1-carbaldehyde2160489-01-8C10H16O2
- 2-tert-Butyl-5-cyclopentyloxolane-3-carboxylic acid2172277-79-9C14H24O3
- 2-Cyclopentyl-5-propyloxolane-3-carboxylic acid2172533-20-7C13H22O3
- 2-Cyclopentyl-5-(methoxymethyl)oxolane-3-carboxylic acid2172568-71-5C12H20O4
- 5-Cyclopentyl-2-(difluoromethyl)oxolane-3-carboxylic acid2172243-28-4C11H16F2O3
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1n[nH]cc1B1OCCO1](/scaffold/BMQOPKIAPDKYOJ-UHFFFAOYSA-N/structure.svg)
c1n[nH]cc1B1OCCO163 chemicals
c1csc(-c2cccs2)c148 chemicals
c1cnn(C2CCCC2)c143 chemicals![Scaffold c1cc(B2OCCO2)n[nH]1](/scaffold/INSYJPNIRNOISO-UHFFFAOYSA-N/structure.svg)
c1cc(B2OCCO2)n[nH]142 chemicals![Scaffold c1csc(-c2cc[nH]n2)c1](/scaffold/TVNDPZYOQCCHTJ-UHFFFAOYSA-N/structure.svg)
c1csc(-c2cc[nH]n2)c135 chemicals
c1ncc(B2OCCO2)s130 chemicals
c1csc(B2OCCO2)c127 chemicals
c1csc(-c2cscn2)c123 chemicals
c1csc(-c2ccno2)c122 chemicals![Scaffold c1coc(-c2cc[nH]n2)c1](/scaffold/XHTWJTDNZKWQON-UHFFFAOYSA-N/structure.svg)
c1coc(-c2cc[nH]n2)c122 chemicals
c1cc(B2OCCO2)cs120 chemicals
c1cn(C2CCCO2)cn119 chemicals