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Murcko scaffold

Ring system with 4 rings and 23 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
12
With full pages
6
Scaffold SMILES

O=C(Nc1nc2ccccc2s1)c1cc2ccccc2[nH]c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nc2ccccc2s1)c1cc2ccccc2[nH]c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

N-(6-Bromo-1,3-benzothiazol-2-yl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C21H18BrN3O3S, CAS 303100-98-3
N-(6-Bromo-1,3-benzothiazol-2-yl)-1-butyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 303100-98-3C21H18BrN3O3S
N-(6-Bromo-1,3-benzothiazol-2-yl)-1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C19H14BrN3O3S, CAS 313518-36-4
N-(6-Bromo-1,3-benzothiazol-2-yl)-1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 313518-36-4C19H14BrN3O3S
N-(6-Bromo-1,3-benzothiazol-2-yl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C20H16BrN3O3S, CAS 313554-65-3
N-(6-Bromo-1,3-benzothiazol-2-yl)-4-hydroxy-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide
CAS 313554-65-3C20H16BrN3O3S
4-Hydroxy-1-methyl-N-(6-methyl-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydro-3-quinolinecarboxamide chemical structure, C19H15N3O3S, CAS 423145-53-3
4-Hydroxy-1-methyl-N-(6-methyl-1,3-benzothiazol-2-yl)-2-oxo-1,2-dihydro-3-quinolinecarboxamide
CAS 423145-53-3C19H15N3O3S
N-(1,3-Benzothiazol-2-yl)-1-ET-4-HO-2-oxo-1,2-dihydro-3-quinolinecarboxamide chemical structure, C19H15N3O3S, CAS 300716-43-2
N-(1,3-Benzothiazol-2-yl)-1-ET-4-HO-2-oxo-1,2-dihydro-3-quinolinecarboxamide
CAS 300716-43-2C19H15N3O3S
N-(6-Bromo-1,3-benzothiazol-2-yl)-4-hydroxy-1-isopentyl-2-oxo-1,2-dihydro-3-quinolinecarboxamide chemical structure, C22H20BrN3O3S, CAS 300717-81-1
N-(6-Bromo-1,3-benzothiazol-2-yl)-4-hydroxy-1-isopentyl-2-oxo-1,2-dihydro-3-quinolinecarboxamide
CAS 300717-81-1C22H20BrN3O3S
N-(1,3-Benzothiazol-2-yl)-4-HO-2-oxo-1-pentyl-1,2-dihydro-3-quinolinecarboxamide chemical structure, C22H21N3O3S, CAS 303093-33-6
N-(1,3-Benzothiazol-2-yl)-4-HO-2-oxo-1-pentyl-1,2-dihydro-3-quinolinecarboxamide
CAS 303093-33-6C22H21N3O3S
N-(6-Fluoro-1,3-benzothiazol-2-yl)-4-hydroxy-1-(2-methylpropyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C21H18FN3O3S, CAS 423145-67-9
N-(6-Fluoro-1,3-benzothiazol-2-yl)-4-hydroxy-1-(2-methylpropyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 423145-67-9C21H18FN3O3S
1-Butyl-4-hydroxy-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C22H21N3O3S, CAS 423145-59-9
1-Butyl-4-hydroxy-N-(6-methylbenzo[d]thiazol-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 423145-59-9C22H21N3O3S
4-Hydroxy-N-(6-methyl-1,3-benzothiazol-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C21H19N3O3S, CAS 423145-56-6
4-Hydroxy-N-(6-methyl-1,3-benzothiazol-2-yl)-2-oxo-1-propyl-1,2-dihydroquinoline-3-carboxamide
CAS 423145-56-6C21H19N3O3S
N-(6-Fluorobenzo[d]thiazol-2-yl)-4-hydroxy-2-oxo-1-pentyl-1,2-dihydroquinoline-3-carboxamide chemical structure, C22H20FN3O3S, CAS 487013-13-8
N-(6-Fluorobenzo[d]thiazol-2-yl)-4-hydroxy-2-oxo-1-pentyl-1,2-dihydroquinoline-3-carboxamide
CAS 487013-13-8C22H20FN3O3S
N-(1,3-Benzothiazol-2-yl)-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamide chemical structure, C18H13N3O3S, CAS 303093-32-5
N-(1,3-Benzothiazol-2-yl)-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
CAS 303093-32-5C18H13N3O3S