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Murcko scaffold

3H-1,2-Dihydro-1-pyrrolizinone scaffold

28 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
28
With full pages
3
Scaffold SMILES

O=C1CCn2cccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3H-1,2-Dihydro-1-pyrrolizinone page
Murcko scaffold O=C1CCn2cccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

3H-1,2-Dihydro-1-pyrrolizinone chemical structure, C7H7NO, CAS 17266-64-7
3H-1,2-Dihydro-1-pyrrolizinone
CAS 17266-64-7C7H7NO
Loroquine chemical structure, C8H9NO2, CAS 27792-82-1
Loroquine
CAS 27792-82-1C8H9NO2
2-(1-Oxo-2,3-dihydro-1H-pyrrolizin-3-yl)acetic acid chemical structure, C9H9NO3, CAS 63547-56-8
2-(1-Oxo-2,3-dihydro-1H-pyrrolizin-3-yl)acetic acid
CAS 63547-56-8C9H9NO3
2,3-Dihydro-7-methyl-1H-pyrrolizin-1-one chemical structure, C8H9NO, CAS 6064-85-3
2,3-Dihydro-7-methyl-1H-pyrrolizin-1-one
CAS 6064-85-3C8H9NO
1-Oxo-2,3-dihydro-1H-pyrrolizine-5-carbaldehyde chemical structure, C8H7NO2, CAS 250355-51-2
1-Oxo-2,3-dihydro-1H-pyrrolizine-5-carbaldehyde
CAS 250355-51-2C8H7NO2
7-[(Acetyloxy)methyl]-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C10H11NO3, CAS 27792-83-2
7-[(Acetyloxy)methyl]-2,3-dihydro-1H-pyrrolizin-1-one
CAS 27792-83-2C10H11NO3
5-Amino-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C7H8N2O, CAS 408493-15-2
5-Amino-2,3-dihydro-1H-pyrrolizin-1-one
CAS 408493-15-2C7H8N2O
7-(Ethoxymethyl)-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C10H13NO2, CAS 113963-36-3
7-(Ethoxymethyl)-2,3-dihydro-1H-pyrrolizin-1-one
CAS 113963-36-3C10H13NO2
5-Acetyl-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C9H9NO2, CAS 118097-03-3
5-Acetyl-2,3-dihydro-1H-pyrrolizin-1-one
CAS 118097-03-3C9H9NO2
2,3-Dihydro-5-nitro-1H-pyrrolizin-1-one chemical structure, C7H6N2O3, CAS 54906-43-3
2,3-Dihydro-5-nitro-1H-pyrrolizin-1-one
CAS 54906-43-3C7H6N2O3
6-Amino-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C7H8N2O, CAS 408493-16-3
6-Amino-2,3-dihydro-1H-pyrrolizin-1-one
CAS 408493-16-3C7H8N2O
7-Amino-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C7H8N2O, CAS 408493-17-4
7-Amino-2,3-dihydro-1H-pyrrolizin-1-one
CAS 408493-17-4C7H8N2O
1-Oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylic acid chemical structure, C8H7NO3, CAS 716362-06-0
1-Oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylic acid
CAS 716362-06-0C8H7NO3
1-Oxo-2,3-dihydro-1H-pyrrolizine-7-carbaldehyde chemical structure, C8H7NO2, CAS 27792-84-3
1-Oxo-2,3-dihydro-1H-pyrrolizine-7-carbaldehyde
CAS 27792-84-3C8H7NO2
2-(Aminomethyl)-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C8H10N2O, CAS 189262-82-6
2-(Aminomethyl)-2,3-dihydro-1H-pyrrolizin-1-one
CAS 189262-82-6C8H10N2O
(S)-1-Oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylic acid chemical structure, C8H7NO3, CAS 80314-88-1
(S)-1-Oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylic acid
CAS 80314-88-1C8H7NO3
(S)-Methyl 1-oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylate chemical structure, C9H9NO3, CAS 80314-99-4
(S)-Methyl 1-oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylate
CAS 80314-99-4C9H9NO3
Methyl 1-oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylate chemical structure, C9H9NO3, CAS 80314-96-1
Methyl 1-oxo-2,3-dihydro-1H-pyrrolizine-3-carboxylate
CAS 80314-96-1C9H9NO3
(1-Oxo-2,3-dihydro-1H-pyrrolizin-2-yl)acetonitrile chemical structure, C9H8N2O, CAS 189262-81-5
(1-Oxo-2,3-dihydro-1H-pyrrolizin-2-yl)acetonitrile
CAS 189262-81-5C9H8N2O
6-Bromo-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C7H6BrNO, CAS 51333-68-7
6-Bromo-2,3-dihydro-1H-pyrrolizin-1-one
CAS 51333-68-7C7H6BrNO
5-Bromo-2,3-dihydro-1H-pyrrolizin-1-one chemical structure, C7H6BrNO, CAS 1415034-30-8
5-Bromo-2,3-dihydro-1H-pyrrolizin-1-one
CAS 1415034-30-8C7H6BrNO
5-Methyl-2,3-dihydropyrrolizin-1-one chemical structure, C8H9NO, CAS 1415034-28-4
5-Methyl-2,3-dihydropyrrolizin-1-one
CAS 1415034-28-4C8H9NO
7-Oxo-5,6-dihydropyrrolizine-3-carbonitrile chemical structure, C8H6N2O, CAS 2685871-50-3
7-Oxo-5,6-dihydropyrrolizine-3-carbonitrile
CAS 2685871-50-3C8H6N2O
Methyl 1-oxo-2,3-dihydro-1H-pyrrolizine-5-carboxylate chemical structure, C9H9NO3, CAS 3069824-58-1
Methyl 1-oxo-2,3-dihydro-1H-pyrrolizine-5-carboxylate
CAS 3069824-58-1C9H9NO3