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Murcko scaffold

Ring system with 4 rings and 20 atoms

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
16
With full pages
1
Scaffold SMILES

c1cc(B2OCCO2)c2cnn(C3CCCCO3)c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(B2OCCO2)c2cnn(C3CCCCO3)c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

(1-(Tetrahydro-2H-pyran-2-yl)-1H-indazol-4-yl)boronic acid pinacol ester chemical structure, C18H25BN2O3, CAS 956388-05-9
(1-(Tetrahydro-2H-pyran-2-yl)-1H-indazol-4-yl)boronic acid pinacol ester
CAS 956388-05-9C18H25BN2O3
1-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-1H-indazole chemical structure, C19H24BF3N2O3, CAS 1454301-68-8
1-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-1H-indazole
CAS 1454301-68-8C19H24BF3N2O3
5-Isopropyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C21H31BN2O3, CAS 2768872-96-2
5-Isopropyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2768872-96-2C21H31BN2O3
5-Methyl-1-(oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C19H27BN2O3, CAS 1698028-42-0
5-Methyl-1-(oxan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 1698028-42-0C19H27BN2O3
1-Tetrahydropyran-2-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)indazole chemical structure, C19H24BF3N2O3, CAS 2621939-51-1
1-Tetrahydropyran-2-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)indazole
CAS 2621939-51-1C19H24BF3N2O3
6-Fluoro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C19H26BFN2O3, CAS 2241720-68-1
6-Fluoro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2241720-68-1C19H26BFN2O3
5-Chloro-6-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C19H26BClN2O3, CAS 2374152-77-7
5-Chloro-6-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2374152-77-7C19H26BClN2O3
3-Chloro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C19H26BClN2O3, CAS 2368910-16-9
3-Chloro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2368910-16-9C19H26BClN2O3
5-Chloro-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C18H24BClN2O3, CAS 2241721-09-3
5-Chloro-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2241721-09-3C18H24BClN2O3
6-Chloro-5-methyl-1-tetrahydropyran-2-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole chemical structure, C19H26BClN2O3, CAS 2374152-83-5
6-Chloro-5-methyl-1-tetrahydropyran-2-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole
CAS 2374152-83-5C19H26BClN2O3
5,6-Dimethyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C20H29BN2O3, CAS 2621935-44-0
5,6-Dimethyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2621935-44-0C20H29BN2O3
6-Methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C19H27BN2O3, CAS 2621939-52-2
6-Methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2621939-52-2C19H27BN2O3
1-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethoxy)-1H-indazole chemical structure, C19H24BF3N2O4, CAS 2621935-74-6
1-(Tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethoxy)-1H-indazole
CAS 2621935-74-6C19H24BF3N2O4
5,6-Dichloro-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole chemical structure, C18H23BCl2N2O3, CAS 2653202-57-2
5,6-Dichloro-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS 2653202-57-2C18H23BCl2N2O3
5-Chloro-6-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-4-boronic Acid Pinacol Ester chemical structure, C18H23BClFN2O3, CAS 2852766-65-3
5-Chloro-6-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-4-boronic Acid Pinacol Ester
CAS 2852766-65-3C18H23BClFN2O3
5-Chloro-1-tetrahydropyran-2-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)indazole chemical structure, C19H23BClF3N2O3, CAS 3040185-40-5
5-Chloro-1-tetrahydropyran-2-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)indazole
CAS 3040185-40-5C19H23BClF3N2O3