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Murcko scaffold

1,5,6,7-Tetrahydro-4H-indol-4-one scaffold

96 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
96
With full pages
17
Scaffold SMILES

O=C1CCCc2[nH]ccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,5,6,7-Tetrahydro-4H-indol-4-one page
Murcko scaffold O=C1CCCc2[nH]ccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 96 chemicals

Indol-4(5H)-one, 6,7-dihydro-2,3-dimethyl- chemical structure, C10H13NO, CAS 6116-75-2
Indol-4(5H)-one, 6,7-dihydro-2,3-dimethyl-
CAS 6116-75-2C10H13NO
Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, ethyl ester chemical structure, C12H15NO3, CAS 7272-58-4
Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-methyl-4-oxo-, ethyl ester
CAS 7272-58-4C12H15NO3
4H-Indol-4-one, 1,5,6,7-tetrahydro-1,2,3-trimethyl- chemical structure, C11H15NO, CAS 7273-21-4
4H-Indol-4-one, 1,5,6,7-tetrahydro-1,2,3-trimethyl-
CAS 7273-21-4C11H15NO
Indol-4(5H)-one, 2-acetyl-6,7-dihydro-3-methyl- chemical structure, C11H13NO2, CAS 14006-80-5
Indol-4(5H)-one, 2-acetyl-6,7-dihydro-3-methyl-
CAS 14006-80-5C11H13NO2
Indol-4(5H)-one, 3-acetyl-6,7-dihydro- chemical structure, C10H11NO2, CAS 22056-54-8
Indol-4(5H)-one, 3-acetyl-6,7-dihydro-
CAS 22056-54-8C10H11NO2
3-Ethyl-2-methyl-1,5,6,7-tetrahydroindol-4-one chemical structure, C11H15NO, CAS 6116-76-3
3-Ethyl-2-methyl-1,5,6,7-tetrahydroindol-4-one
CAS 6116-76-3C11H15NO
C 8778-GO chemical structure, C17H25NO3, CAS 121625-71-6
C 8778-GO
CAS 121625-71-6C17H25NO3
1-Isobutyl-2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-3-indoleacetic acid chemical structure, C17H25NO3, CAS 121625-72-7
1-Isobutyl-2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-3-indoleacetic acid
CAS 121625-72-7C17H25NO3
1-Methyl-6,7-dihydro-1H-indol-4(5H)-one chemical structure, C9H11NO, CAS 51471-08-0
1-Methyl-6,7-dihydro-1H-indol-4(5H)-one
CAS 51471-08-0C9H11NO
1,6,6-Trimethyl-5,7-dihydroindol-4-one chemical structure, C11H15NO, CAS 20955-76-4
1,6,6-Trimethyl-5,7-dihydroindol-4-one
CAS 20955-76-4C11H15NO
1,5,6,7-Tetrahydro-4H-indol-4-one chemical structure, C8H9NO, CAS 13754-86-4
1,5,6,7-Tetrahydro-4H-indol-4-one
CAS 13754-86-4C8H9NO
1,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-3-yl acetate chemical structure, C13H17NO3, CAS 41312-37-2
1,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-3-yl acetate
CAS 41312-37-2C13H17NO3
Ethyl 1,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate chemical structure, C13H17NO3, CAS 14006-82-7
Ethyl 1,3-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate
CAS 14006-82-7C13H17NO3
Ethyl 5-cyano-1,3-dimethyl-4-oxo-6,7-dihydro-5H-indole-2-carboxylate chemical structure, C14H16N2O3, CAS 84990-20-5
Ethyl 5-cyano-1,3-dimethyl-4-oxo-6,7-dihydro-5H-indole-2-carboxylate
CAS 84990-20-5C14H16N2O3
Ethyl 1,3-dimethyl-4-oxo-5-(3-oxobutyl)-6,7-dihydro-5H-indole-2-carboxylate chemical structure, C17H23NO4, CAS 54874-75-8
Ethyl 1,3-dimethyl-4-oxo-5-(3-oxobutyl)-6,7-dihydro-5H-indole-2-carboxylate
CAS 54874-75-8C17H23NO4
Diethyl 1,3-dimethyl-4-oxo-6,7-dihydro-5H-indole-2,5-dicarboxylate chemical structure, C16H21NO5, CAS 84990-25-0
Diethyl 1,3-dimethyl-4-oxo-6,7-dihydro-5H-indole-2,5-dicarboxylate
CAS 84990-25-0C16H21NO5
1-Hydroxy-2,6,6-trimethyl-3-(2,2,2-trichloroethyl)-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C13H16Cl3NO2, CAS 447433-73-0
1-Hydroxy-2,6,6-trimethyl-3-(2,2,2-trichloroethyl)-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 447433-73-0C13H16Cl3NO2
3-Methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid chemical structure, C10H11NO3, CAS 6577-89-5
3-Methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid
CAS 6577-89-5C10H11NO3
2,6,6-Trimethyl-6,7-dihydro-1H-indol-4(5H)-one chemical structure, C11H15NO, CAS 69595-03-5
2,6,6-Trimethyl-6,7-dihydro-1H-indol-4(5H)-one
CAS 69595-03-5C11H15NO
2,6,6-Trimethyl-1-pentyl-3-(2,2,2-trichloroethyl)-5,7-dihydroindol-4-one chemical structure, C18H26Cl3NO, CAS 426824-05-7
2,6,6-Trimethyl-1-pentyl-3-(2,2,2-trichloroethyl)-5,7-dihydroindol-4-one
CAS 426824-05-7C18H26Cl3NO
3,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid chemical structure, C12H15NO3, CAS 129689-88-9
3,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid
CAS 129689-88-9C12H15NO3
Ethyl 3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate chemical structure, C14H19NO3, CAS 37711-24-3
Ethyl 3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate
CAS 37711-24-3C14H19NO3
6,6-Dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C10H13NO, CAS 20955-75-3
6,6-Dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 20955-75-3C10H13NO
Dimethyl 3,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2,5-dicarboxylate chemical structure, C14H17NO5, CAS 702665-69-8
Dimethyl 3,6-dimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2,5-dicarboxylate
CAS 702665-69-8C14H17NO5