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Murcko scaffold

Ring system with 2 rings and 10 atoms

31 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
31
With full pages
4
Scaffold SMILES

C1COC2COCOC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1COC2COCOC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

4,6-O-Ethylidene-alpha-D-glucopyranose chemical structure, C8H14O6, CAS 13224-99-2
4,6-O-Ethylidene-alpha-D-glucopyranose
CAS 13224-99-2C8H14O6
Methyl 4,6-O-(1-carboxyethylidene)galactopyranoside chemical structure, C10H16O8, CAS 92569-54-5
Methyl 4,6-O-(1-carboxyethylidene)galactopyranoside
CAS 92569-54-5C10H16O8
alpha-D-Galactopyranose, 4,6-O-(1-carboxyethylidene)-, (R)- chemical structure, C9H14O8, CAS 82597-50-0
alpha-D-Galactopyranose, 4,6-O-(1-carboxyethylidene)-, (R)-
CAS 82597-50-0C9H14O8
D-Glucopyranose, 4,6-O-ethylidene- chemical structure, C8H14O6, CAS 18465-50-4
D-Glucopyranose, 4,6-O-ethylidene-
CAS 18465-50-4C8H14O6
4-Methoxy-5,8,10-trioxabicyclo[4.4.0]decane-2,3-diol chemical structure, C8H14O6, CAS 50256-48-9
4-Methoxy-5,8,10-trioxabicyclo[4.4.0]decane-2,3-diol
CAS 50256-48-9C8H14O6
Methyl 2,3-di-O-acetyl-4,6-O-methylidenehexopyranoside chemical structure, C12H18O8, CAS 50256-56-9
Methyl 2,3-di-O-acetyl-4,6-O-methylidenehexopyranoside
CAS 50256-56-9C12H18O8
(6,7-Diacetyloxy-2,2-dimethyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl) acetate chemical structure, C15H22O9, CAS 50605-20-4
(6,7-Diacetyloxy-2,2-dimethyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl) acetate
CAS 50605-20-4C15H22O9
1,3-Di-O-acetyl-2-deoxy-2-[(1-hydroxyethylidene)amino]-4,6-O-(1-methylethylidene)hexopyranose chemical structure, C15H23NO8, CAS 50605-10-2
1,3-Di-O-acetyl-2-deoxy-2-[(1-hydroxyethylidene)amino]-4,6-O-(1-methylethylidene)hexopyranose
CAS 50605-10-2C15H23NO8
Methyl 4,6-O-[(1R)-1-carboxyethylidene]-beta-D-galactopyranoside chemical structure, C10H16O8, CAS 72698-47-6
Methyl 4,6-O-[(1R)-1-carboxyethylidene]-beta-D-galactopyranoside
CAS 72698-47-6C10H16O8
4,6-Ethylidene glucose streptozotocin chemical structure, C10H17N3O7, CAS 121230-21-5
4,6-Ethylidene glucose streptozotocin
CAS 121230-21-5C10H17N3O7
Etoposide impurity 26 chemical structure, C8H14O6, CAS 2089582-90-9
Etoposide impurity 26
CAS 2089582-90-9C8H14O6
(4aR,6R,7R,8R,8aS)-7-Amino-2,2-dimethyl-6-(2-trimethylsilylethoxy)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-ol chemical structure, C14H29NO5Si, CAS 122078-72-2
(4aR,6R,7R,8R,8aS)-7-Amino-2,2-dimethyl-6-(2-trimethylsilylethoxy)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-ol
CAS 122078-72-2C14H29NO5Si
beta-D-Glucopyranose, 4,6-O-ethylidene-1-O-(trimethylsilyl)-, bis(dichloroacetate) chemical structure, C15H22Cl4O8Si, CAS 149312-24-3
beta-D-Glucopyranose, 4,6-O-ethylidene-1-O-(trimethylsilyl)-, bis(dichloroacetate)
CAS 149312-24-3C15H22Cl4O8Si
2-Acetamido-2-deoxy-4,6-o-isopropylidene-D-glucopyranose chemical structure, C11H19NO6, CAS 50605-09-9
2-Acetamido-2-deoxy-4,6-o-isopropylidene-D-glucopyranose
CAS 50605-09-9C11H19NO6
[(2R,4aR,6R,7R,8S,8aR)-7-(2-Chloroacetyl)oxy-6-hydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] 2-chloroacetate chemical structure, C12H16Cl2O8, CAS 92206-84-3
[(2R,4aR,6R,7R,8S,8aR)-7-(2-Chloroacetyl)oxy-6-hydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] 2-chloroacetate
CAS 92206-84-3C12H16Cl2O8
(4aR,6R,7R,8R,8aR)-6-Methoxy-2,2-dimethyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol chemical structure, C10H18O6, CAS 20688-90-8
(4aR,6R,7R,8R,8aR)-6-Methoxy-2,2-dimethyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol
CAS 20688-90-8C10H18O6
1,2,3-TRI-O-ACETYL-4,6-O-ETHYLIDENE-Beta-D-GLUCOPYRANOSE chemical structure, C14H20O9, CAS 27994-30-5
1,2,3-TRI-O-ACETYL-4,6-O-ETHYLIDENE-Beta-D-GLUCOPYRANOSE
CAS 27994-30-5C14H20O9
[(4aR,6R,7R,8S,8aR)-7-(2,2-Dichloroacetyl)oxy-6-hydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] 2,2-dichloroacetate chemical structure, C12H14Cl4O8, CAS 149403-65-6
[(4aR,6R,7R,8S,8aR)-7-(2,2-Dichloroacetyl)oxy-6-hydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] 2,2-dichloroacetate
CAS 149403-65-6C12H14Cl4O8
[(4aR,6R,7R,8S,8aR)-7-Acetoxy-6-fluoro-2-propyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] acetate chemical structure, C14H21FO7, CAS 129439-77-6
[(4aR,6R,7R,8S,8aR)-7-Acetoxy-6-fluoro-2-propyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] acetate
CAS 129439-77-6C14H21FO7
Allyl 2-deoxy-4,6-O-isopropylidene-2-(trifluoroacetamido)-a-D-glucopyranoside chemical structure, C14H20F3NO6, CAS 139629-59-7
Allyl 2-deoxy-4,6-O-isopropylidene-2-(trifluoroacetamido)-a-D-glucopyranoside
CAS 139629-59-7C14H20F3NO6
Plasmalopsychosine B chemical structure, C40H77NO7, CAS 142506-75-0
Plasmalopsychosine B
CAS 142506-75-0C40H77NO7
b-D-Glucopyranose,2-(acetylamino)-2-deoxy-4,6-O-(1-methylethylidene)- chemical structure, C13H21NO7
b-D-Glucopyranose,2-(acetylamino)-2-deoxy-4,6-O-(1-methylethylidene)-
C13H21NO7
4-Methoxy-9-methyl-2-(2-sulfanylethylamino)-5,8,10-trioxabicyclo[4.4.0]decan-3-ol chemical structure, C11H22ClNO5S, CAS 6964-94-9
4-Methoxy-9-methyl-2-(2-sulfanylethylamino)-5,8,10-trioxabicyclo[4.4.0]decan-3-ol
CAS 6964-94-9C11H22ClNO5S
Methyl 4,6-O-isopropylidene-A-D-mannopyranoside chemical structure, C10H18O6, CAS 63167-67-9
Methyl 4,6-O-isopropylidene-A-D-mannopyranoside
CAS 63167-67-9C10H18O6