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Murcko scaffold

Ring system with 2 rings and 14 atoms

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
17
With full pages
6
Scaffold SMILES

O=c1[nH]cncc1Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cncc1Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-Amino-5-[(3,4-dichlorophenyl)amino]-6-hydroxypyrimidin-4(3H)-one chemical structure, C10H8Cl2N4O2, CAS 7400-35-3
2-Amino-5-[(3,4-dichlorophenyl)amino]-6-hydroxypyrimidin-4(3H)-one
CAS 7400-35-3C10H8Cl2N4O2
2-Amino-6-hydroxy-5-(3-methylanilino)pyrimidin-4(3H)-one chemical structure, C11H12N4O2, CAS 91952-14-6
2-Amino-6-hydroxy-5-(3-methylanilino)pyrimidin-4(3H)-one
CAS 91952-14-6C11H12N4O2
2-Amino-4,6-dihydroxy-5-pyrimidinyl(3-methylphenyl)formamide chemical structure, C12H12N4O3, CAS 6939-53-3
2-Amino-4,6-dihydroxy-5-pyrimidinyl(3-methylphenyl)formamide
CAS 6939-53-3C12H12N4O3
2-Amino-5-(2-ethoxyanilino)-4-hydroxy-1H-pyrimidin-6-one chemical structure, C12H14N4O3, CAS 6952-57-4
2-Amino-5-(2-ethoxyanilino)-4-hydroxy-1H-pyrimidin-6-one
CAS 6952-57-4C12H14N4O3
5-((3-Chlorophenyl)amino)-6-hydroxy-2-(methylthio)pyrimidin-4(3H)-one chemical structure, C11H10ClN3O2S, CAS 7400-19-3
5-((3-Chlorophenyl)amino)-6-hydroxy-2-(methylthio)pyrimidin-4(3H)-one
CAS 7400-19-3C11H10ClN3O2S
6-Hydroxy-5-(m-tolylamino)pyrimidin-4(3H)-one chemical structure, C11H11N3O2, CAS 7400-21-7
6-Hydroxy-5-(m-tolylamino)pyrimidin-4(3H)-one
CAS 7400-21-7C11H11N3O2
5-[(4-Chlorophenyl)amino]-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one chemical structure, C11H10ClN3O2S, CAS 6630-69-9
5-[(4-Chlorophenyl)amino]-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 6630-69-9C11H10ClN3O2S
6-Hydroxy-2-(methylthio)-5-(phenylamino)pyrimidin-4(3H)-one chemical structure, C11H11N3O2S, CAS 92290-01-2
6-Hydroxy-2-(methylthio)-5-(phenylamino)pyrimidin-4(3H)-one
CAS 92290-01-2C11H11N3O2S
6-Hydroxy-5-(3-methylanilino)-2-(methylsulfanyl)pyrimidin-4(3H)-one chemical structure, C12H13N3O2S, CAS 88617-72-5
6-Hydroxy-5-(3-methylanilino)-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 88617-72-5C12H13N3O2S
5-[(4-Bromophenyl)amino]-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one chemical structure, C11H10BrN3O2S, CAS 6972-11-8
5-[(4-Bromophenyl)amino]-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 6972-11-8C11H10BrN3O2S
5-(3,4-Dichloroanilino)-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one chemical structure, C11H9Cl2N3O2S, CAS 91064-37-8
5-(3,4-Dichloroanilino)-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 91064-37-8C11H9Cl2N3O2S
5-[(3,4-Dimethylphenyl)amino]-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one chemical structure, C13H15N3O2S, CAS 6972-20-9
5-[(3,4-Dimethylphenyl)amino]-6-hydroxy-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 6972-20-9C13H15N3O2S
4-Hydroxy-5-(4-methylanilino)-1H-pyrimidin-6-one chemical structure, C11H11N3O2, CAS 6972-22-1
4-Hydroxy-5-(4-methylanilino)-1H-pyrimidin-6-one
CAS 6972-22-1C11H11N3O2
5-((3,4-Dimethylphenyl)amino)-6-hydroxypyrimidin-4(3H)-one chemical structure, C12H13N3O2, CAS 6972-23-2
5-((3,4-Dimethylphenyl)amino)-6-hydroxypyrimidin-4(3H)-one
CAS 6972-23-2C12H13N3O2
5-((3-Chlorophenyl)amino)-6-hydroxypyrimidin-4(3H)-one chemical structure, C10H8ClN3O2, CAS 6972-24-3
5-((3-Chlorophenyl)amino)-6-hydroxypyrimidin-4(3H)-one
CAS 6972-24-3C10H8ClN3O2
5-((2-Ethoxyphenyl)amino)-6-hydroxypyrimidin-4(3H)-one chemical structure, C12H13N3O3, CAS 6972-25-4
5-((2-Ethoxyphenyl)amino)-6-hydroxypyrimidin-4(3H)-one
CAS 6972-25-4C12H13N3O3
5-(3-Bromophenylamino)pyrimidine-4,6-diol chemical structure, C10H8BrN3O2, CAS 454685-37-1
5-(3-Bromophenylamino)pyrimidine-4,6-diol
CAS 454685-37-1C10H8BrN3O2