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Murcko scaffold

4-Phenyl-2-(4-pyridyl)thiazole scaffold

41 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
41
With full pages
6
Scaffold SMILES

c1ccc(-c2csc(-c3ccncc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-2-(4-pyridyl)thiazole page
Murcko scaffold c1ccc(-c2csc(-c3ccncc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

4-Phenyl-2-(4-pyridyl)thiazole chemical structure, C14H10N2S, CAS 106950-18-9
4-Phenyl-2-(4-pyridyl)thiazole
CAS 106950-18-9C14H10N2S
4-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C16H14N2S, CAS 430441-82-0
4-[4-(4-Ethylphenyl)-1,3-thiazol-2-yl]pyridine
CAS 430441-82-0C16H14N2S
4-{4-[2,3-Dichloro-4-(ethylsulfonyl)phenyl]-1,3-thiazol-2-yl}pyridine chemical structure, C16H12Cl2N2O2S2, CAS 672951-46-1
4-{4-[2,3-Dichloro-4-(ethylsulfonyl)phenyl]-1,3-thiazol-2-yl}pyridine
CAS 672951-46-1C16H12Cl2N2O2S2
Fatostatin chemical structure, C18H18N2S, CAS 125256-00-0
Fatostatin
CAS 125256-00-0C18H18N2S
2,6-Dichloro-4-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C14H6Cl2F2N2S, CAS 680215-80-9
2,6-Dichloro-4-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]pyridine
CAS 680215-80-9C14H6Cl2F2N2S
2,6-Dichloro-4-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C14H7Cl2FN2S, CAS 680215-88-7
2,6-Dichloro-4-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]pyridine
CAS 680215-88-7C14H7Cl2FN2S
2,6-Dichloro-4-{4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}pyridine chemical structure, C15H7Cl2F3N2S, CAS 680215-90-1
2,6-Dichloro-4-{4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}pyridine
CAS 680215-90-1C15H7Cl2F3N2S
4-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-propylpyridine hydrobromide chemical structure, C17H16Br2N2S, CAS 298197-06-5
4-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-propylpyridine hydrobromide
CAS 298197-06-5C17H16Br2N2S
2-(2-Propylpyridin-4-yl)-4-p-tolylthiazole hydrobromide chemical structure, C18H19BrN2S, CAS 298197-04-3
2-(2-Propylpyridin-4-yl)-4-p-tolylthiazole hydrobromide
CAS 298197-04-3C18H19BrN2S
4-(4-(4-Nitrophenyl)-1,3-thiazol-2-yl]-2-propylpyridine hydrobromide chemical structure, C17H16BrN3O2S, CAS 298197-07-6
4-(4-(4-Nitrophenyl)-1,3-thiazol-2-yl]-2-propylpyridine hydrobromide
CAS 298197-07-6C17H16BrN3O2S
3-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]aniline chemical structure, C14H11N3S, CAS 134812-31-0
3-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]aniline
CAS 134812-31-0C14H11N3S
Ethyl 4-[2-(4-pyridinyl)-4-thiazolyl]benzoate chemical structure, C17H14N2O2S, CAS 773042-01-6
Ethyl 4-[2-(4-pyridinyl)-4-thiazolyl]benzoate
CAS 773042-01-6C17H14N2O2S
N-(4-(2-(2-Propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide chemical structure, C18H19N3O2S2, CAS 1046045-61-7
N-(4-(2-(2-Propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide
CAS 1046045-61-7C18H19N3O2S2
{4-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]phenyl}methanamine chemical structure, C15H13N3S, CAS 1018637-66-5
{4-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]phenyl}methanamine
CAS 1018637-66-5C15H13N3S
4-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]benzonitrile chemical structure, C15H9N3S, CAS 222629-39-2
4-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]benzonitrile
CAS 222629-39-2C15H9N3S
5-Methyl-4-phenyl-2-(4-pyridyl)thiazole chemical structure, C15H12N2S, CAS 1217863-43-8
5-Methyl-4-phenyl-2-(4-pyridyl)thiazole
CAS 1217863-43-8C15H12N2S
2-{4-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]phenyl}acetic acid chemical structure, C16H12N2O2S, CAS 1018637-78-9
2-{4-[2-(Pyridin-4-yl)-1,3-thiazol-4-yl]phenyl}acetic acid
CAS 1018637-78-9C16H12N2O2S
2-(2-Chloropyridin-4-yl)-4-(p-tolyl)thiazole chemical structure, C15H11ClN2S, CAS 1181547-19-2
2-(2-Chloropyridin-4-yl)-4-(p-tolyl)thiazole
CAS 1181547-19-2C15H11ClN2S
4-(4-Chlorophenyl)-2-(2-chloropyridin-4-yl)thiazole chemical structure, C14H8Cl2N2S, CAS 1431729-96-2
4-(4-Chlorophenyl)-2-(2-chloropyridin-4-yl)thiazole
CAS 1431729-96-2C14H8Cl2N2S
2-(2-Chloropyridin-4-yl)-4-(4-fluorophenyl)thiazole chemical structure, C14H8ClFN2S, CAS 1431728-63-0
2-(2-Chloropyridin-4-yl)-4-(4-fluorophenyl)thiazole
CAS 1431728-63-0C14H8ClFN2S
2-(2-Chloropyridin-4-yl)-4-phenylthiazole chemical structure, C14H9ClN2S, CAS 1431728-42-5
2-(2-Chloropyridin-4-yl)-4-phenylthiazole
CAS 1431728-42-5C14H9ClN2S
Ethyl 4-phenyl-2-(pyridin-4-yl)thiazole-5-carboxylate chemical structure, C17H14N2O2S, CAS 228413-59-0
Ethyl 4-phenyl-2-(pyridin-4-yl)thiazole-5-carboxylate
CAS 228413-59-0C17H14N2O2S
4-Phenyl-2-(4-pyridinyl)-5-thiazolamine chemical structure, C14H11N3S, CAS 873581-46-5
4-Phenyl-2-(4-pyridinyl)-5-thiazolamine
CAS 873581-46-5C14H11N3S
1-(5-Bromo-4-(4-phenylthiazol-2-yl)pyridin-2-yl)-3-ethylurea chemical structure, C17H15BrN4OS, CAS 1031432-16-2
1-(5-Bromo-4-(4-phenylthiazol-2-yl)pyridin-2-yl)-3-ethylurea
CAS 1031432-16-2C17H15BrN4OS