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Murcko scaffold

Ring system with 2 rings and 15 atoms

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
23
With full pages
5
Scaffold SMILES

O=C(Nc1cnc[nH]c1=O)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cnc[nH]c1=O)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-(2-(Allylthio)-4-amino-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide chemical structure, C12H12N4O3S, CAS 868225-86-9
N-(2-(Allylthio)-4-amino-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
CAS 868225-86-9C12H12N4O3S
N-(4-Amino-2-(butylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide chemical structure, C13H16N4O3S, CAS 868225-85-8
N-(4-Amino-2-(butylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
CAS 868225-85-8C13H16N4O3S
Ethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoate chemical structure, C14H16N4O5S, CAS 868226-69-1
Ethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoate
CAS 868226-69-1C14H16N4O5S
N-(4-Amino-2-((2-amino-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide chemical structure, C11H11N5O4S, CAS 868225-93-8
N-(4-Amino-2-((2-amino-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
CAS 868225-93-8C11H11N5O4S
N-(4-Amino-2-((2,4-dioxopentan-3-yl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide chemical structure, C14H14N4O5S, CAS 868226-76-0
N-(4-Amino-2-((2,4-dioxopentan-3-yl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
CAS 868226-76-0C14H14N4O5S
Diethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)malonate chemical structure, C16H18N4O7S, CAS 868226-74-8
Diethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)malonate
CAS 868226-74-8C16H18N4O7S
Ethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate chemical structure, C15H18N4O5S, CAS 868226-70-4
Ethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate
CAS 868226-70-4C15H18N4O5S
Methyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate chemical structure, C14H16N4O5S, CAS 868226-71-5
Methyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate
CAS 868226-71-5C14H16N4O5S
Methyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate chemical structure, C12H12N4O5S, CAS 868226-67-9
Methyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate
CAS 868226-67-9C12H12N4O5S
Ethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate chemical structure, C13H14N4O5S, CAS 868226-68-0
Ethyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate
CAS 868226-68-0C13H14N4O5S
Methyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoate chemical structure, C13H14N4O5S, CAS 868226-72-6
Methyl 2-((4-amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoate
CAS 868226-72-6C13H14N4O5S
N-(4-Amino-2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide chemical structure, C10H10N4O3S, CAS 868225-82-5
N-(4-Amino-2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
CAS 868225-82-5C10H10N4O3S
N-(4-Amino-2-((2-(methylamino)-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide chemical structure, C12H13N5O4S, CAS 888423-09-4
N-(4-Amino-2-((2-(methylamino)-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
CAS 888423-09-4C12H13N5O4S
2-((4-Amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetic acid chemical structure, C11H10N4O5S, CAS 888424-43-9
2-((4-Amino-5-(furan-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetic acid
CAS 888424-43-9C11H10N4O5S
N-(4-Amino-2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide chemical structure, C10H9BrN4O3S, CAS 888425-39-6
N-(4-Amino-2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide
CAS 888425-39-6C10H9BrN4O3S
N-(4-Amino-2-(ethylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide chemical structure, C11H11BrN4O3S, CAS 888425-45-4
N-(4-Amino-2-(ethylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide
CAS 888425-45-4C11H11BrN4O3S
N-(4-Amino-2-((2-hydroxyethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide chemical structure, C11H11BrN4O4S, CAS 888426-05-9
N-(4-Amino-2-((2-hydroxyethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide
CAS 888426-05-9C11H11BrN4O4S
N-(4-Amino-2-((2-amino-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide chemical structure, C11H10BrN5O4S, CAS 888427-02-9
N-(4-Amino-2-((2-amino-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide
CAS 888427-02-9C11H10BrN5O4S
2-((4-Amino-5-(5-bromofuran-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetic acid chemical structure, C11H9BrN4O5S, CAS 888433-48-5
2-((4-Amino-5-(5-bromofuran-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetic acid
CAS 888433-48-5C11H9BrN4O5S
N-(4-Amino-2-((2-hydroxyethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide chemical structure, C11H12N4O4S, CAS 872608-58-7
N-(4-Amino-2-((2-hydroxyethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)furan-2-carboxamide
CAS 872608-58-7C11H12N4O4S
2-((4-Amino-5-(5-bromofuran-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoic acid chemical structure, C12H11BrN4O5S, CAS 888433-55-4
2-((4-Amino-5-(5-bromofuran-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoic acid
CAS 888433-55-4C12H11BrN4O5S
2-((4-Amino-5-(5-bromofuran-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoic acid chemical structure, C13H13BrN4O5S, CAS 888433-62-3
2-((4-Amino-5-(5-bromofuran-2-carboxamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoic acid
CAS 888433-62-3C13H13BrN4O5S
N-(4-Amino-2-((2-(diethylamino)-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide chemical structure, C15H18BrN5O4S, CAS 888430-98-6
N-(4-Amino-2-((2-(diethylamino)-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-5-bromofuran-2-carboxamide
CAS 888430-98-6C15H18BrN5O4S