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Murcko scaffold

4-(2-Thienyl)pyridine scaffold

94 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
94
With full pages
7
Scaffold SMILES

c1csc(-c2ccncc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Thienyl)pyridine page
Murcko scaffold c1csc(-c2ccncc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 94 chemicals

2-(1-Methylpyridin-4(1H)-ylidene)-2H-thiophen-1-ium iodide chemical structure, C10H10INS, CAS 27058-43-1
2-(1-Methylpyridin-4(1H)-ylidene)-2H-thiophen-1-ium iodide
CAS 27058-43-1C10H10INS
4-(2-Thienyl)pyridine chemical structure, C9H7NS, CAS 21298-54-4
4-(2-Thienyl)pyridine
CAS 21298-54-4C9H7NS
2-Amino-6-(butylsulfanyl)-4-(2-thienyl)-3,5-pyridinedicarbonitrile chemical structure, C15H14N4S2, CAS 445381-58-8
2-Amino-6-(butylsulfanyl)-4-(2-thienyl)-3,5-pyridinedicarbonitrile
CAS 445381-58-8C15H14N4S2
Dimethyl 2,6-dimethyl-4-(2-thienyl)pyridine-3,5-dicarboxylate chemical structure, C15H15NO4S, CAS 219701-24-3
Dimethyl 2,6-dimethyl-4-(2-thienyl)pyridine-3,5-dicarboxylate
CAS 219701-24-3C15H15NO4S
2-Amino-6-methylsulfanyl-4-thiophen-2-ylpyridine-3,5-dicarbonitrile chemical structure, C12H8N4S2, CAS 342388-11-8
2-Amino-6-methylsulfanyl-4-thiophen-2-ylpyridine-3,5-dicarbonitrile
CAS 342388-11-8C12H8N4S2
2-Amino-6-(cyanomethylsulfanyl)-4-thiophen-2-ylpyridine-3,5-dicarbonitrile chemical structure, C13H7N5S2, CAS 316362-18-2
2-Amino-6-(cyanomethylsulfanyl)-4-thiophen-2-ylpyridine-3,5-dicarbonitrile
CAS 316362-18-2C13H7N5S2
Ethyl 4-((3-cyano-6-methyl-4-(thiophen-2-yl)pyridin-2-yl)thio)-3-oxobutanoate chemical structure, C17H16N2O3S2, CAS 445265-65-6
Ethyl 4-((3-cyano-6-methyl-4-(thiophen-2-yl)pyridin-2-yl)thio)-3-oxobutanoate
CAS 445265-65-6C17H16N2O3S2
2-(6-Amino-3,5-dicyano-4-thiophen-2-ylpyridin-2-yl)sulfanyl-N-tert-butylacetamide chemical structure, C17H17N5OS2, CAS 445381-56-6
2-(6-Amino-3,5-dicyano-4-thiophen-2-ylpyridin-2-yl)sulfanyl-N-tert-butylacetamide
CAS 445381-56-6C17H17N5OS2
2-(Allylthio)-6-amino-4-(thiophen-2-yl)pyridine-3,5-dicarbonitrile chemical structure, C14H10N4S2, CAS 310454-11-6
2-(Allylthio)-6-amino-4-(thiophen-2-yl)pyridine-3,5-dicarbonitrile
CAS 310454-11-6C14H10N4S2
Propan-2-yl 2-(6-amino-3,5-dicyano-4-thiophen-2-ylpyridin-2-yl)sulfanylacetate chemical structure, C16H14N4O2S2, CAS 342392-12-5
Propan-2-yl 2-(6-amino-3,5-dicyano-4-thiophen-2-ylpyridin-2-yl)sulfanylacetate
CAS 342392-12-5C16H14N4O2S2
2,6-Dimethyl-4-(thiophen-2-yl)pyridine chemical structure, C11H11NS, CAS 50581-77-6
2,6-Dimethyl-4-(thiophen-2-yl)pyridine
CAS 50581-77-6C11H11NS
5-Pyridin-4-yl-thiophene-2-sulfonyl chloride chemical structure, C9H6ClNO2S2, CAS 205055-48-7
5-Pyridin-4-yl-thiophene-2-sulfonyl chloride
CAS 205055-48-7C9H6ClNO2S2
3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-thienyl)-, diethyl ester chemical structure, C17H19NO4S, CAS 94675-54-4
3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-thienyl)-, diethyl ester
CAS 94675-54-4C17H19NO4S
5-(Pyridin-4-yl)thiophene-2-carbaldehyde chemical structure, C10H7NOS, CAS 129770-69-0
5-(Pyridin-4-yl)thiophene-2-carbaldehyde
CAS 129770-69-0C10H7NOS
2-Methoxy-4-(2-thienyl)-3-pyridinecarbonitrile chemical structure, C11H8N2OS, CAS 149379-72-6
2-Methoxy-4-(2-thienyl)-3-pyridinecarbonitrile
CAS 149379-72-6C11H8N2OS
4-(4-Bromo-5-methylthiophen-2-yl)pyridine chemical structure, C10H8BrNS, CAS 154566-70-8
4-(4-Bromo-5-methylthiophen-2-yl)pyridine
CAS 154566-70-8C10H8BrNS
Ethyl 3-amino-5-(pyridin-4-yl)thiophene-2-carboxylate chemical structure, C12H12N2O2S, CAS 83739-57-5
Ethyl 3-amino-5-(pyridin-4-yl)thiophene-2-carboxylate
CAS 83739-57-5C12H12N2O2S
3-Amino-5-(pyridin-4-yl)thiophene-2-carboxylic acid chemical structure, C10H8N2O2S, CAS 83739-50-8
3-Amino-5-(pyridin-4-yl)thiophene-2-carboxylic acid
CAS 83739-50-8C10H8N2O2S
Diethyl 4-thiophen-2-yl-2,6-bis(trifluoromethyl)pyridine-3,5-dicarboxylate chemical structure, C17H13F6NO4S, CAS 97887-68-8
Diethyl 4-thiophen-2-yl-2,6-bis(trifluoromethyl)pyridine-3,5-dicarboxylate
CAS 97887-68-8C17H13F6NO4S
4-(Thiophen-2-yl)nicotinic acid chemical structure, C10H7NO2S, CAS 1261970-02-8
4-(Thiophen-2-yl)nicotinic acid
CAS 1261970-02-8C10H7NO2S
4-(5-Methyl-2-thienyl)pyridine chemical structure, C10H9NS, CAS 129770-70-3
4-(5-Methyl-2-thienyl)pyridine
CAS 129770-70-3C10H9NS
Ethyl 2-amino-5-(pyridin-4-yl)thiophene-3-carboxylate chemical structure, C12H12N2O2S, CAS 139355-52-5
Ethyl 2-amino-5-(pyridin-4-yl)thiophene-3-carboxylate
CAS 139355-52-5C12H12N2O2S
4-(5-Bromothiophen-2-yl)pyridine chemical structure, C9H6BrNS, CAS 164936-60-1
4-(5-Bromothiophen-2-yl)pyridine
CAS 164936-60-1C9H6BrNS
4-[5-(Dimethylamino)thiophen-2-yl]-1-methylpyridin-1-ium chemical structure, C12H15N2S+, CAS 211373-90-9
4-[5-(Dimethylamino)thiophen-2-yl]-1-methylpyridin-1-ium
CAS 211373-90-9C12H15N2S+