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Murcko scaffold

4-(2-Thienyl)pyridine scaffold

94 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
94
With full pages
7
Scaffold SMILES

c1csc(-c2ccncc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Thienyl)pyridine page
Murcko scaffold c1csc(-c2ccncc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 94 of 94 chemicals

Ethyl 5-(3-cyano-pyridin-4-yl)thiophene-2-carboxylate chemical structure, C13H10N2O2S, CAS 1035235-02-9
Ethyl 5-(3-cyano-pyridin-4-yl)thiophene-2-carboxylate
CAS 1035235-02-9C13H10N2O2S
5-(2-Methoxy-4-pyridinyl)-2-thiophenecarboxylic acid chemical structure, C11H9NO3S, CAS 1555189-77-9
5-(2-Methoxy-4-pyridinyl)-2-thiophenecarboxylic acid
CAS 1555189-77-9C11H9NO3S
6-tert-Butyl-2-methyl-4-(thiophen-2-yl)pyridine-3-carbonitrile chemical structure, C15H16N2S, CAS 650605-96-2
6-tert-Butyl-2-methyl-4-(thiophen-2-yl)pyridine-3-carbonitrile
CAS 650605-96-2C15H16N2S
2,6-Dimethyl-4-(thiophen-2-yl)pyridine-3-carbonitrile chemical structure, C12H10N2S, CAS 650605-92-8
2,6-Dimethyl-4-(thiophen-2-yl)pyridine-3-carbonitrile
CAS 650605-92-8C12H10N2S
4-(4-Bromo-3,5-dimethylthiophen-2-yl)pyridine chemical structure, C11H10BrNS, CAS 921596-27-2
4-(4-Bromo-3,5-dimethylthiophen-2-yl)pyridine
CAS 921596-27-2C11H10BrNS
1-(5-(Pyridin-4-yl)thiophen-2-yl)ethan-1-amine chemical structure, C11H12N2S, CAS 1515969-77-3
1-(5-(Pyridin-4-yl)thiophen-2-yl)ethan-1-amine
CAS 1515969-77-3C11H12N2S
4-(Thiophen-2-yl)pyridin-3-amine chemical structure, C9H8N2S, CAS 1048960-62-8
4-(Thiophen-2-yl)pyridin-3-amine
CAS 1048960-62-8C9H8N2S
4-(Thiophen-2-yl)pyridine-2-carbonitrile chemical structure, C10H6N2S, CAS 1782908-56-8
4-(Thiophen-2-yl)pyridine-2-carbonitrile
CAS 1782908-56-8C10H6N2S
2-Amino-4-(5-bromothienyl-2-yl)pyridine chemical structure, C9H7BrN2S, CAS 1563531-21-4
2-Amino-4-(5-bromothienyl-2-yl)pyridine
CAS 1563531-21-4C9H7BrN2S
4-(3-Methylthiophen-2-yl)pyridin-2-amine chemical structure, C10H10N2S, CAS 1592901-68-2
4-(3-Methylthiophen-2-yl)pyridin-2-amine
CAS 1592901-68-2C10H10N2S
5-(2-Methyl-4-pyridinyl)-2-thiophenecarboxylic acid chemical structure, C11H9NO2S, CAS 1599350-88-5
5-(2-Methyl-4-pyridinyl)-2-thiophenecarboxylic acid
CAS 1599350-88-5C11H9NO2S
tert-Butyl 3-amino-5-(pyridin-4-yl)thiophene-2-carboxylate chemical structure, C14H16N2O2S, CAS 1772340-80-3
tert-Butyl 3-amino-5-(pyridin-4-yl)thiophene-2-carboxylate
CAS 1772340-80-3C14H16N2O2S
4-(5-Ethynylthiophen-2-yl)pyridine chemical structure, C11H7NS, CAS 2097967-74-1
4-(5-Ethynylthiophen-2-yl)pyridine
CAS 2097967-74-1C11H7NS
5-Bromo-2-amino-4-(2-thienyl)pyridine chemical structure, C9H7BrN2S, CAS 1381942-01-3
5-Bromo-2-amino-4-(2-thienyl)pyridine
CAS 1381942-01-3C9H7BrN2S
2,5-Dibromo-4-(2-thienyl)pyridine chemical structure, C9H5Br2NS, CAS 1381933-54-5
2,5-Dibromo-4-(2-thienyl)pyridine
CAS 1381933-54-5C9H5Br2NS
2,3-Dibromo-4-(2-thienyl)pyridine chemical structure, C9H5Br2NS, CAS 1381941-07-6
2,3-Dibromo-4-(2-thienyl)pyridine
CAS 1381941-07-6C9H5Br2NS
2-Amino-3-bromo-4-(2-thienyl)pyridine chemical structure, C9H7BrN2S, CAS 1381938-02-8
2-Amino-3-bromo-4-(2-thienyl)pyridine
CAS 1381938-02-8C9H7BrN2S
3-Bromo-4-(2-thienyl)pyridine chemical structure, C9H6BrNS, CAS 1374664-35-3
3-Bromo-4-(2-thienyl)pyridine
CAS 1374664-35-3C9H6BrNS
2-Bromo-5-amino-4-(2-thienyl)pyridine chemical structure, C9H7BrN2S, CAS 1381934-97-9
2-Bromo-5-amino-4-(2-thienyl)pyridine
CAS 1381934-97-9C9H7BrN2S
3-Bromo-4-(2-thienyl)-2-pyridinecarbonitrile chemical structure, C10H5BrN2S, CAS 1622843-07-5
3-Bromo-4-(2-thienyl)-2-pyridinecarbonitrile
CAS 1622843-07-5C10H5BrN2S
3-Bromo-4-(2-thienyl)-2-chloropyridine chemical structure, C9H5BrClNS, CAS 1622843-15-5
3-Bromo-4-(2-thienyl)-2-chloropyridine
CAS 1622843-15-5C9H5BrClNS
2-Bromo-3-fluoro-4-(2-thienyl)pyridine chemical structure, C9H5BrFNS, CAS 1622840-48-5
2-Bromo-3-fluoro-4-(2-thienyl)pyridine
CAS 1622840-48-5C9H5BrFNS
2-Fluoro-3-bromo-4-(2-thienyl)pyridine chemical structure, C9H5BrFNS, CAS 1622843-67-7
2-Fluoro-3-bromo-4-(2-thienyl)pyridine
CAS 1622843-67-7C9H5BrFNS
5-Pyridin-4-ylthiophene-2-carbonitrile chemical structure, C10H6N2S, CAS 911466-81-4
5-Pyridin-4-ylthiophene-2-carbonitrile
CAS 911466-81-4C10H6N2S