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Murcko scaffold

2-Thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline scaffold

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
15
With full pages
7
Scaffold SMILES

O=S(=O)(c1cccs1)N1CCc2ccccc2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline page
Murcko scaffold O=S(=O)(c1cccs1)N1CCc2ccccc2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

2-Thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline chemical structure, C13H13NO2S2, CAS 326007-89-0
2-Thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline
CAS 326007-89-0C13H13NO2S2
(3S)-2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chemical structure, C14H13NO4S2, CAS 1212436-25-3
(3S)-2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
CAS 1212436-25-3C14H13NO4S2
(3R)-2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid chemical structure, C14H13NO4S2, CAS 2389466-54-8
(3R)-2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
CAS 2389466-54-8C14H13NO4S2
2-[(5-Chlorothiophen-2-yl)sulfonyl]-1,2,3,4-tetrahydroisoquinoline chemical structure, C13H12ClNO2S2, CAS 385407-79-4
2-[(5-Chlorothiophen-2-yl)sulfonyl]-1,2,3,4-tetrahydroisoquinoline
CAS 385407-79-4C13H12ClNO2S2
2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid chemical structure, C14H13NO4S2, CAS 1008267-14-8
2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid
CAS 1008267-14-8C14H13NO4S2
Ethyl ({[2-(2-thienylsulfonyl)-1,2,3,4-tetrahydro-3-isoquinolinyl]carbonyl}amino)acetate chemical structure, C18H20N2O5S2, CAS 1008667-14-8
Ethyl ({[2-(2-thienylsulfonyl)-1,2,3,4-tetrahydro-3-isoquinolinyl]carbonyl}amino)acetate
CAS 1008667-14-8C18H20N2O5S2
N-tert-Butyl-2-thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide chemical structure, C18H22N2O3S2, CAS 1008243-80-8
N-tert-Butyl-2-thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide
CAS 1008243-80-8C18H22N2O3S2
N-Butyl-2-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide chemical structure, C18H22N2O3S2, CAS 1008014-95-6
N-Butyl-2-(thiophen-2-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CAS 1008014-95-6C18H22N2O3S2
2-[2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl]acetic acid chemical structure, C15H15NO4S2, CAS 327971-33-5
2-[2-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl]acetic acid
CAS 327971-33-5C15H15NO4S2
6,7-Dimethoxy-1-methyl-2-thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline chemical structure, C16H19NO4S2, CAS 883950-85-4
6,7-Dimethoxy-1-methyl-2-thiophen-2-ylsulfonyl-3,4-dihydro-1H-isoquinoline
CAS 883950-85-4C16H19NO4S2
2-[5-(1,2,3,4-Tetrahydroisoquinoline-2-sulfonyl)thiophen-2-yl]acetic acid chemical structure, C15H15NO4S2, CAS 923913-14-8
2-[5-(1,2,3,4-Tetrahydroisoquinoline-2-sulfonyl)thiophen-2-yl]acetic acid
CAS 923913-14-8C15H15NO4S2
5-(1,2,3,4-Tetrahydroisoquinoline-2-sulfonyl)thiophene-3-carboxylic acid chemical structure, C14H13NO4S2, CAS 924062-42-0
5-(1,2,3,4-Tetrahydroisoquinoline-2-sulfonyl)thiophene-3-carboxylic acid
CAS 924062-42-0C14H13NO4S2
2-[(5-Chloro-2-thienyl)sulfonyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline chemical structure, C15H16ClNO4S2, CAS 924843-18-5
2-[(5-Chloro-2-thienyl)sulfonyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
CAS 924843-18-5C15H16ClNO4S2
7-Nitro-2-(thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinoline chemical structure, C13H12N2O4S2, CAS 1170229-59-0
7-Nitro-2-(thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinoline
CAS 1170229-59-0C13H12N2O4S2
2-[(5-Fluorothiophen-2-yl)sulfonyl]-1,2,3,4-tetrahydroisoquinoline chemical structure, C13H12FNO2S2, CAS 1855890-87-7
2-[(5-Fluorothiophen-2-yl)sulfonyl]-1,2,3,4-tetrahydroisoquinoline
CAS 1855890-87-7C13H12FNO2S2