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Murcko scaffold

Ring system with 3 rings and 19 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
7
With full pages
3
Scaffold SMILES

O=C1CCC(=O)C1CC=C1CCCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC(=O)C1CC=C1CCCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

13-Ethyl-3-methoxy-8,14-secogona-1,3,5(10)-9-tetraene-14,17-dion chemical structure, C20H24O3, CAS 850-92-0
13-Ethyl-3-methoxy-8,14-secogona-1,3,5(10)-9-tetraene-14,17-dion
CAS 850-92-0C20H24O3
2-[2-(6-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-2-methylcyclopentane-1,3-dione chemical structure, C19H22O3
2-[2-(6-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)ethyl]-2-methylcyclopentane-1,3-dione
C19H22O3
2-((2E)-2-(6-Methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl)-2-methylcyclopentane-1,3-dione chemical structure, C19H22O3, CAS 899-79-6
2-((2E)-2-(6-Methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl)-2-methylcyclopentane-1,3-dione
CAS 899-79-6C19H22O3
2-((2E)-2-(3,4-Dihydro-6-methoxy-1(2H)-naphthalenylidene)ethyl)-2-ethyl-1,3-cyclopentanedione chemical structure, C20H24O3, CAS 62298-52-6
2-((2E)-2-(3,4-Dihydro-6-methoxy-1(2H)-naphthalenylidene)ethyl)-2-ethyl-1,3-cyclopentanedione
CAS 62298-52-6C20H24O3
2-[2-(3,4-Dihydro-6-methoxy-1(2H)-naphthalenylidene)ethyl]-2-(1-methylethyl)-1,3-cyclopentanedione chemical structure, C21H26O3, CAS 17421-99-7
2-[2-(3,4-Dihydro-6-methoxy-1(2H)-naphthalenylidene)ethyl]-2-(1-methylethyl)-1,3-cyclopentanedione
CAS 17421-99-7C21H26O3
2-[2-(3,4-Dihydro-5,7-dimethoxy-1(2H)-naphthalenylidene)ethyl]-2-methyl-1,3-cyclopentanedione chemical structure, C20H24O4, CAS 33758-72-4
2-[2-(3,4-Dihydro-5,7-dimethoxy-1(2H)-naphthalenylidene)ethyl]-2-methyl-1,3-cyclopentanedione
CAS 33758-72-4C20H24O4
2-[2-(3,4-Dihydro-6,7-dimethoxy-1(2H)-naphthalenylidene)ethyl]-2-ethyl-1,3-cyclopentanedione chemical structure, C21H26O4, CAS 17422-00-3
2-[2-(3,4-Dihydro-6,7-dimethoxy-1(2H)-naphthalenylidene)ethyl]-2-ethyl-1,3-cyclopentanedione
CAS 17422-00-3C21H26O4