CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

100 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
100
With full pages
19
Scaffold SMILES

O=C(C=Cc1ccccc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 100 chemicals

1-(2,6-Dimethylpiperidin-1-yl)-3-phenylprop-2-en-1-one chemical structure, C16H21NO, CAS 20351-86-4
1-(2,6-Dimethylpiperidin-1-yl)-3-phenylprop-2-en-1-one
CAS 20351-86-4C16H21NO
Piperidine, 1-(3-(4-chlorophenyl)-1-oxo-2-propenyl)- chemical structure, C14H16ClNO, CAS 17123-82-9
Piperidine, 1-(3-(4-chlorophenyl)-1-oxo-2-propenyl)-
CAS 17123-82-9C14H16ClNO
(2E)-3-(2-Chlorophenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one chemical structure, C15H18ClNO, CAS 300822-62-2
(2E)-3-(2-Chlorophenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one
CAS 300822-62-2C15H18ClNO
(E)-3-(3-Bromo-4-methoxyphenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one chemical structure, C16H20BrNO2, CAS 302574-16-9
(E)-3-(3-Bromo-4-methoxyphenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one
CAS 302574-16-9C16H20BrNO2
(E)-3-(4-Ethoxy-3-methoxyphenyl)-1-piperidin-1-ylprop-2-en-1-one chemical structure, C17H23NO3, CAS 347365-04-2
(E)-3-(4-Ethoxy-3-methoxyphenyl)-1-piperidin-1-ylprop-2-en-1-one
CAS 347365-04-2C17H23NO3
(E)-3-(4-Ethoxy-3-methoxyphenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one chemical structure, C18H25NO3, CAS 302807-70-1
(E)-3-(4-Ethoxy-3-methoxyphenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one
CAS 302807-70-1C18H25NO3
(E)-3-(2,4-Dimethoxyphenyl)-1-(piperidin-1-yl)prop-2-en-1-one chemical structure, C16H21NO3, CAS 127006-84-2
(E)-3-(2,4-Dimethoxyphenyl)-1-(piperidin-1-yl)prop-2-en-1-one
CAS 127006-84-2C16H21NO3
Piperidine, 1-[3-(4-methoxyphenyl)-1-oxo-2-propenyl]- chemical structure, C15H19NO2, CAS 74957-45-2
Piperidine, 1-[3-(4-methoxyphenyl)-1-oxo-2-propenyl]-
CAS 74957-45-2C15H19NO2
(E)-3-Phenyl-1-piperidin-1-ylprop-2-en-1-one chemical structure, C14H17NO, CAS 5422-81-1
(E)-3-Phenyl-1-piperidin-1-ylprop-2-en-1-one
CAS 5422-81-1C14H17NO
1-[(E)-3-(2-Methoxyphenyl)prop-2-enoyl]piperidine-4-carboxamide chemical structure, C16H20N2O3, CAS 510722-94-8
1-[(E)-3-(2-Methoxyphenyl)prop-2-enoyl]piperidine-4-carboxamide
CAS 510722-94-8C16H20N2O3
(2E)-3-(4-Methoxyphenyl)-1-(piperidin-1-yl)prop-2-en-1-one chemical structure, C15H19NO2, CAS 78932-09-9
(2E)-3-(4-Methoxyphenyl)-1-(piperidin-1-yl)prop-2-en-1-one
CAS 78932-09-9C15H19NO2
1-[(2E)-3-(4-Methoxyphenyl)prop-2-enoyl]piperidine-4-carboxamide chemical structure, C16H20N2O3, CAS 543696-81-7
1-[(2E)-3-(4-Methoxyphenyl)prop-2-enoyl]piperidine-4-carboxamide
CAS 543696-81-7C16H20N2O3
(E)-3-(4-Fluorophenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one chemical structure, C15H18FNO, CAS 853347-69-0
(E)-3-(4-Fluorophenyl)-1-(4-methylpiperidin-1-yl)prop-2-en-1-one
CAS 853347-69-0C15H18FNO
(E)-3-(4-Methylphenyl)-1-piperidin-1-ylprop-2-en-1-one chemical structure, C15H19NO, CAS 1648627-28-4
(E)-3-(4-Methylphenyl)-1-piperidin-1-ylprop-2-en-1-one
CAS 1648627-28-4C15H19NO
Ethyl 1-[(2E)-3-(3-nitrophenyl)prop-2-enoyl]piperidine-4-carboxylate chemical structure, C17H20N2O5, CAS 6097-73-0
Ethyl 1-[(2E)-3-(3-nitrophenyl)prop-2-enoyl]piperidine-4-carboxylate
CAS 6097-73-0C17H20N2O5
Methyl 1-[(2E)-3-(4-nitrophenyl)prop-2-enoyl]piperidine-4-carboxylate chemical structure, C16H18N2O5, CAS 587844-63-1
Methyl 1-[(2E)-3-(4-nitrophenyl)prop-2-enoyl]piperidine-4-carboxylate
CAS 587844-63-1C16H18N2O5
(E)-3-(2-Nitrophenyl)-1-piperidin-1-ylprop-2-en-1-one chemical structure, C14H16N2O3, CAS 116576-38-6
(E)-3-(2-Nitrophenyl)-1-piperidin-1-ylprop-2-en-1-one
CAS 116576-38-6C14H16N2O3
Methyl 1-[(2E)-3-(2-nitrophenyl)prop-2-enoyl]piperidine-4-carboxylate chemical structure, C16H18N2O5, CAS 600123-87-3
Methyl 1-[(2E)-3-(2-nitrophenyl)prop-2-enoyl]piperidine-4-carboxylate
CAS 600123-87-3C16H18N2O5
Piperidine, 1-(3,4,5-trimethoxycinnamoyl)- chemical structure, C17H23NO4, CAS 970-85-4
Piperidine, 1-(3,4,5-trimethoxycinnamoyl)-
CAS 970-85-4C17H23NO4
Ethyl 1-[3-(4-fluorophenyl)prop-2-enoyl]piperidine-4-carboxylate chemical structure, C17H20FNO3, CAS 380568-65-0
Ethyl 1-[3-(4-fluorophenyl)prop-2-enoyl]piperidine-4-carboxylate
CAS 380568-65-0C17H20FNO3
1-Piperidino-3-(4-butoxyphenyl)-2-propene-1-one chemical structure, C18H25NO2, CAS 105151-27-7
1-Piperidino-3-(4-butoxyphenyl)-2-propene-1-one
CAS 105151-27-7C18H25NO2
3-(4-Hydroxy-3,5-dimethylphenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile chemical structure, C17H20N2O2, CAS 518984-90-2
3-(4-Hydroxy-3,5-dimethylphenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile
CAS 518984-90-2C17H20N2O2
3-[4-(Difluoromethoxy)phenyl]-2-(piperidine-1-carbonyl)prop-2-enenitrile chemical structure, C16H16F2N2O2, CAS 326188-65-2
3-[4-(Difluoromethoxy)phenyl]-2-(piperidine-1-carbonyl)prop-2-enenitrile
CAS 326188-65-2C16H16F2N2O2
1-(3,4-Dimethoxycinnamoyl)piperidine chemical structure, C16H21NO3, CAS 128261-84-7
1-(3,4-Dimethoxycinnamoyl)piperidine
CAS 128261-84-7C16H21NO3