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Murcko scaffold

Ring system with 3 rings and 15 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
19
With full pages
4
Scaffold SMILES

c1cc2c(cc1B1OCCO1)CCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2c(cc1B1OCCO1)CCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-(3,4-Dihydro-2H-1-benzopyran-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C15H21BO3, CAS 1002727-88-9
2-(3,4-Dihydro-2H-1-benzopyran-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1002727-88-9C15H21BO3
4,4,5,5-Tetramethyl-2-(5-methylchroman-6-yl)-1,3,2-dioxaborolane chemical structure, C16H23BO3, CAS 1154740-74-5
4,4,5,5-Tetramethyl-2-(5-methylchroman-6-yl)-1,3,2-dioxaborolane
CAS 1154740-74-5C16H23BO3
2-(7-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C15H20BFO3, CAS 1154741-03-3
2-(7-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1154741-03-3C15H20BFO3
2-(8-Chloro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C16H22BClO3, CAS 1154740-73-4
2-(8-Chloro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1154740-73-4C16H22BClO3
2-(4,4-Difluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C15H19BF2O3, CAS 1154741-11-3
2-(4,4-Difluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1154741-11-3C15H19BF2O3
2-(5-Chlorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C15H20BClO3, CAS 1154740-54-1
2-(5-Chlorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1154740-54-1C15H20BClO3
2-(8-Fluoro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C16H22BFO3, CAS 1154741-05-5
2-(8-Fluoro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1154741-05-5C16H22BFO3
2-(5-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C15H20BFO3, CAS 1154741-08-8
2-(5-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1154741-08-8C15H20BFO3
5-Chloro-8-fluoro-3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1-benzopyran chemical structure, C15H19BClFO3, CAS 1154741-06-6
5-Chloro-8-fluoro-3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1-benzopyran
CAS 1154741-06-6C15H19BClFO3
8-(1,1-Dimethylethyl)-3,4-dihydro-4,4-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1-benzopyran chemical structure, C21H33BO3, CAS 1402888-66-7
8-(1,1-Dimethylethyl)-3,4-dihydro-4,4-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1-benzopyran
CAS 1402888-66-7C21H33BO3
tert-Butyl N-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-1-benzopyran-4-yl]carbamate chemical structure, C20H30BNO5, CAS 2300106-61-8
tert-Butyl N-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-1-benzopyran-4-yl]carbamate
CAS 2300106-61-8C20H30BNO5
N,N-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)chromane-2-carboxamide chemical structure, C18H26BNO4, CAS 1614233-68-9
N,N-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)chromane-2-carboxamide
CAS 1614233-68-9C18H26BNO4
2-(8-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C15H20BFO3, CAS 1594126-53-0
2-(8-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 1594126-53-0C15H20BFO3
2-Methoxycarbonyl-3,4-dihydro-2H-benzopyran-6-boronic acid pinacol ester chemical structure, C17H23BO5, CAS 2152654-65-2
2-Methoxycarbonyl-3,4-dihydro-2H-benzopyran-6-boronic acid pinacol ester
CAS 2152654-65-2C17H23BO5
3-[6-(4,4,5,5-Tetramethyl[1,3,2]dioxaborolan-2-yl)chroman-2-yl]propionic acid ethyl ester chemical structure, C20H29BO5, CAS 1958099-14-3
3-[6-(4,4,5,5-Tetramethyl[1,3,2]dioxaborolan-2-yl)chroman-2-yl]propionic acid ethyl ester
CAS 1958099-14-3C20H29BO5
3,4-Dihydro-4,4-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1-benzopyran chemical structure, C17H25BO3, CAS 1883286-17-6
3,4-Dihydro-4,4-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1-benzopyran
CAS 1883286-17-6C17H25BO3
[6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-1-benzopyran-2-yl]methanol chemical structure, C16H23BO4, CAS 2152654-66-3
[6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-1-benzopyran-2-yl]methanol
CAS 2152654-66-3C16H23BO4
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman-4-ol chemical structure, C15H21BO4, CAS 1939174-72-7
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman-4-ol
CAS 1939174-72-7C15H21BO4
4-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)chroman-4-ol chemical structure, C16H23BO4, CAS 1939174-73-8
4-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)chroman-4-ol
CAS 1939174-73-8C16H23BO4