Murcko scaffold
Octahydro-1H-pyrrolo[3,4-b]pyridine scaffold
75 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 75
- With full pages
- 7
Scaffold SMILES
C1CNC2CNCC2C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 75 chemicals
(4aR,7aR)-Octahydro-1H-pyrrolo(3,4-b)pyridine
CAS 151213-42-2C7H14N2
![tert-Butyl (4aS,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate chemical structure, C12H22N2O2, CAS 1932299-66-5](/s/LGEWGFOMLJQHLL-UWVGGRQHSA-N.svg)
tert-Butyl (4aS,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate
CAS 1932299-66-5C12H22N2O2
![(4aS,7aS)-tert-Butyl octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate chemical structure, C12H22N2O2, CAS 159991-07-8](/s/LGEWGFOMLJQHLL-VHSXEESVSA-N.svg)
(4aS,7aS)-tert-Butyl octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate
CAS 159991-07-8C12H22N2O2
rel-1,1-Dimethylethyl (4aR,7aR)-octahydro-1H-pyrrolo(3,4-b)pyridine-1-carboxylate
CAS 181141-40-2C12H22N2O2
![tert-Butyl (4aR,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate chemical structure, C12H22N2O2, CAS 1368142-11-3](/s/LGEWGFOMLJQHLL-NXEZZACHSA-N.svg)
tert-Butyl (4aR,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate
CAS 1368142-11-3C12H22N2O2
(4aS,7aS)-6-Methyl-octahydro-1H-pyrrolo(3,4-b)pyridine
CAS 1909286-87-8C8H16N2
![Octahydro-1H-pyrrolo[3,4-b]pyridine chemical structure, C7H14N2, CAS 5654-94-4](/s/KSCPLKVBWDOSAI-UHFFFAOYSA-N.svg)
Octahydro-1H-pyrrolo[3,4-b]pyridine
CAS 5654-94-4C7H14N2
(4aS,7aR)-Octahydro-1H-pyrrolo(3,4-b)pyridine
CAS 169533-56-6C7H14N2
(1S,6S)-2,8-Diazabicyclo(4.3.0)nonane
CAS 151213-40-0C7H14N2
![1-((4AR,7aR)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)ethanone chemical structure, C9H16N2O, CAS 220505-47-5](/s/SQSQXLWKABIKHW-BDAKNGLRSA-N.svg)
1-((4AR,7aR)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)ethanone
CAS 220505-47-5C9H16N2O
![1-Methyloctahydropyrrolo[3,4-b]pyridine chemical structure, C8H16N2, CAS 128740-18-1](/s/QVLUVOZDWSAEIP-UHFFFAOYSA-N.svg)
1-Methyloctahydropyrrolo[3,4-b]pyridine
CAS 128740-18-1C8H16N2
![6-Methyloctahydro-1H-pyrrolo[3,4-b]pyridine chemical structure, C8H16N2, CAS 885959-20-6](/s/ACSQOHDWJKTBRH-UHFFFAOYSA-N.svg)
6-Methyloctahydro-1H-pyrrolo[3,4-b]pyridine
CAS 885959-20-6C8H16N2
![3-Methyl-octahydro-1H-pyrrolo[3,4-B]pyridine chemical structure, C8H16N2, CAS 477350-96-2](/s/RZCTVHVCNKXEJK-UHFFFAOYSA-N.svg)
3-Methyl-octahydro-1H-pyrrolo[3,4-B]pyridine
CAS 477350-96-2C8H16N2
1-Boc-octahydropyrrolo(3,4-b)pyridine
CAS 186201-89-8C12H22N2O2
![trans-Octahydro-1H-pyrrolo[3,4-b]pyridine chemical structure, C7H14N2, CAS 169533-55-5](/s/KSCPLKVBWDOSAI-RNFRBKRXSA-N.svg)
trans-Octahydro-1H-pyrrolo[3,4-b]pyridine
CAS 169533-55-5C7H14N2
![6-Ethyloctahydropyrrolo[3,4-B]pyridine chemical structure, C9H18N2, CAS 1141669-88-6](/s/FZQMPENIEFPXAB-UHFFFAOYSA-N.svg)
6-Ethyloctahydropyrrolo[3,4-B]pyridine
CAS 1141669-88-6C9H18N2
![(4AS,7aS)-1-methyloctahydro-1H-pyrrolo[3,4-b]pyridine chemical structure, C8H16N2, CAS 151213-45-5](/s/QVLUVOZDWSAEIP-JGVFFNPUSA-N.svg)
(4AS,7aS)-1-methyloctahydro-1H-pyrrolo[3,4-b]pyridine
CAS 151213-45-5C8H16N2
![6-Methyloctahydro-1H-pyrrolo[3,4-B]pyridine dihydrochloride chemical structure, C8H18Cl2N2, CAS 1211594-26-1](/s/OLSPYLJJOKFQFD-UHFFFAOYSA-N.svg)
6-Methyloctahydro-1H-pyrrolo[3,4-B]pyridine dihydrochloride
CAS 1211594-26-1C8H18Cl2N2
![(4aR,7aR)-6-Methyl-octahydro-1H-pyrrolo[3,4-b]pyridine chemical structure, C8H16N2, CAS 1486465-48-8](/s/ACSQOHDWJKTBRH-SFYZADRCSA-N.svg)
(4aR,7aR)-6-Methyl-octahydro-1H-pyrrolo[3,4-b]pyridine
CAS 1486465-48-8C8H16N2
![cis-1-Methyloctahydropyrrolo[3,4-b]pyridine chemical structure, C8H16N2, CAS 858420-27-6](/s/QVLUVOZDWSAEIP-SFYZADRCSA-N.svg)
cis-1-Methyloctahydropyrrolo[3,4-b]pyridine
CAS 858420-27-6C8H16N2
![1-((4AS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)ethan-1-one chemical structure, C9H16N2O, CAS 1427465-88-0](/s/MDIYONFONIGRAN-DTWKUNHWSA-N.svg)
1-((4AS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)ethan-1-one
CAS 1427465-88-0C9H16N2O
![1-((4AR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)ethan-1-one chemical structure, C9H16N2O, CAS 845626-20-2](/s/MDIYONFONIGRAN-BDAKNGLRSA-N.svg)
1-((4AR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl)ethan-1-one
CAS 845626-20-2C9H16N2O
![Octahydro-1H-pyrrolo[3,4-b]pyridine dihydrochloride chemical structure, C7H16Cl2N2, CAS 1035271-44-3](/s/PBDBVGLZVIIZNU-UHFFFAOYSA-N.svg)
Octahydro-1H-pyrrolo[3,4-b]pyridine dihydrochloride
CAS 1035271-44-3C7H16Cl2N2
![tert-Butyl hexahydro-1H-pyrrolo[3,4-b]pyridine-6(2H)-carboxylate chemical structure, C12H22N2O2, CAS 186203-81-6](/s/LPNOEYLQBVUWGH-UHFFFAOYSA-N.svg)
tert-Butyl hexahydro-1H-pyrrolo[3,4-b]pyridine-6(2H)-carboxylate
CAS 186203-81-6C12H22N2O2
- rel-(4aR,7aR)-tert-Butyl hexahydro-1H-pyrrolo[3,4-b]pyridine-6(2H)-carboxylate1909294-62-7C12H22N2O2
- tert-Butyl (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine-6-carboxylate1229428-51-6C12H22N2O2
- tert-Butyl 1-(N-aminocarbamimidoyl)-octahydro-1H-pyrrolo[3,4-b]pyridine-6-carboxylate1704281-90-2C13H25N5O2
- tert-Butyl 1-carbamothioyl-octahydro-1H-pyrrolo[3,4-b]pyridine-6-carboxylate1696126-84-7C13H23N3O2S
- 1-(Propan-2-yl)-octahydro-1H-pyrrolo[3,4-b]pyridine1597215-82-1C10H20N2
- tert-Butyl (4aR,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine-6-carboxylate2165466-80-6C12H22N2O2
- tert-Butyl (4aS,7aR)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine-6-carboxylate1229428-75-4C12H22N2O2
- trans-1-Methyloctahydropyrrolo[3,4-b]pyridine1368382-83-5C8H16N2
- 1-Ethyloctahydro-1H-pyrrolo[3,4-b]pyridine1438084-44-6C9H18N2
- Ethyl (4aR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate845626-19-9C10H18N2O2
- rel-N,N-dimethyl-2-((4aR,7aR)-tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)acetamide1422139-92-1C11H21N3O
- (4aR,7aR)-6-Methylsulfonyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine1422132-85-1C8H16N2O2S
- 1-(2-Methylpropyl)-octahydro-1H-pyrrolo[3,4-b]pyridine1599287-73-6C11H22N2
- 1-Propyl-octahydro-1H-pyrrolo[3,4-b]pyridine1597940-28-7C10H20N2
- Moxifloxacin impurity 1252085709-73-3C10H18N2O2
- 1-(2,2-Difluoroethyl)-octahydro-1H-pyrrolo[3,4-b]pyridine1597124-66-7C9H16F2N2
- 2-{Octahydro-1H-pyrrolo[3,4-b]pyridin-1-yl}ethan-1-ol1600014-14-9C9H18N2O
- 1-(2,2,2-Trifluoroethyl)-octahydro-1H-pyrrolo[3,4-b]pyridine1599269-54-1C9H15F3N2
- (4aS,7aS)-6-Methyl-octahydro-1H-pyrrolo[3,4-b]pyridine dihydrochloride1955474-20-0C8H18Cl2N2
- 1H-Pyrrolo[3,4-b]pyridine-1-carboxylic acid, octahydro-4-methoxy-, 1,1-dimethylethyl ester, (4R,4aR,7aR)-rel-1445951-19-8C13H24N2O3
- tert-Butyl octahydro-1H-pyrrolo[3,4-b]pyridine-1-carboxylate hydrochloride2448475-41-8C12H23ClN2O2
- (4aR,7aS)-Octahydro-1H-pyrrolo[3,4-b]pyridine dihydrochloride2306255-12-7C7H16Cl2N2
- N,N,1-Trimethyloctahydro-1H-pyrrolo[3,4-b]pyridin-4-amine2306268-79-9C10H21N3
- (4aS,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine dihydrochloride2306249-33-0C7H16Cl2N2
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