CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
27
With full pages
8
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1cc(C2CC2)[nH]n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1cc(C2CC2)[nH]n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

5-Cyclopropyl-N-[(4-methylphenyl)methylideneamino]-1H-pyrazole-3-carboxamide chemical structure, C15H16N4O, CAS 4317-55-9
5-Cyclopropyl-N-[(4-methylphenyl)methylideneamino]-1H-pyrazole-3-carboxamide
CAS 4317-55-9C15H16N4O
3-Cyclopropyl-N'-[(1E)-1-(4-methoxyphenyl)ethylidene]-1H-pyrazole-5-carbohydrazide chemical structure, C16H18N4O2, CAS 1284276-05-6
3-Cyclopropyl-N'-[(1E)-1-(4-methoxyphenyl)ethylidene]-1H-pyrazole-5-carbohydrazide
CAS 1284276-05-6C16H18N4O2
3-Cyclopropyl-N'-[(E)-(4-fluorophenyl)methylidene]-1H-pyrazole-5-carbohydrazide chemical structure, C14H13FN4O, CAS 306302-20-5
3-Cyclopropyl-N'-[(E)-(4-fluorophenyl)methylidene]-1H-pyrazole-5-carbohydrazide
CAS 306302-20-5C14H13FN4O
5-Cyclopropyl-N-[(E)-1-(3-nitrophenyl)ethylideneamino]-1H-pyrazole-3-carboxamide chemical structure, C15H15N5O3, CAS 5784-80-5
5-Cyclopropyl-N-[(E)-1-(3-nitrophenyl)ethylideneamino]-1H-pyrazole-3-carboxamide
CAS 5784-80-5C15H15N5O3
N-[(E)-1-(4-Chlorophenyl)ethylideneamino]-5-cyclopropyl-1H-pyrazole-3-carboxamide chemical structure, C15H15ClN4O, CAS 5785-35-3
N-[(E)-1-(4-Chlorophenyl)ethylideneamino]-5-cyclopropyl-1H-pyrazole-3-carboxamide
CAS 5785-35-3C15H15ClN4O
(E)-3-Cyclopropyl-N'-(4-ethoxybenzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C16H18N4O2, CAS 5785-42-2
(E)-3-Cyclopropyl-N'-(4-ethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
CAS 5785-42-2C16H18N4O2
N'-[(1E)-1-(4-Bromophenyl)ethylidene]-3-cyclopropyl-1H-pyrazole-5-carbohydrazide chemical structure, C15H15BrN4O, CAS 1285680-57-0
N'-[(1E)-1-(4-Bromophenyl)ethylidene]-3-cyclopropyl-1H-pyrazole-5-carbohydrazide
CAS 1285680-57-0C15H15BrN4O
(E)-N'-(4-Bromobenzylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide chemical structure, C14H13BrN4O, CAS 306302-22-7
(E)-N'-(4-Bromobenzylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide
CAS 306302-22-7C14H13BrN4O
(E)-3-Cyclopropyl-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C17H20N4O4, CAS 306302-47-6
(E)-3-Cyclopropyl-N'-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
CAS 306302-47-6C17H20N4O4
(Z)-3-Cyclopropyl-N'-(1-(3,4-dichlorophenyl)ethylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C15H14Cl2N4O, CAS 634884-23-4
(Z)-3-Cyclopropyl-N'-(1-(3,4-dichlorophenyl)ethylidene)-1H-pyrazole-5-carbohydrazide
CAS 634884-23-4C15H14Cl2N4O
(E)-3-Cyclopropyl-N'-(4-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C15H16N4O2, CAS 306302-13-6
(E)-3-Cyclopropyl-N'-(4-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide
CAS 306302-13-6C15H16N4O2
(E)-3-Cyclopropyl-N'-(4-(dimethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C16H19N5O, CAS 306302-09-0
(E)-3-Cyclopropyl-N'-(4-(dimethylamino)benzylidene)-1H-pyrazole-5-carbohydrazide
CAS 306302-09-0C16H19N5O
(E)-3-Cyclopropyl-N'-(3,4-dimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C16H18N4O3, CAS 306302-36-3
(E)-3-Cyclopropyl-N'-(3,4-dimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
CAS 306302-36-3C16H18N4O3
(E)-N'-(4-Butoxybenzylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide chemical structure, C18H22N4O2, CAS 634884-37-0
(E)-N'-(4-Butoxybenzylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide
CAS 634884-37-0C18H22N4O2
(E)-3-Cyclopropyl-N'-(4-(pentyloxy)benzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C19H24N4O2, CAS 1284276-18-1
(E)-3-Cyclopropyl-N'-(4-(pentyloxy)benzylidene)-1H-pyrazole-5-carbohydrazide
CAS 1284276-18-1C19H24N4O2
(E)-3-Cyclopropyl-N'-(2-ethoxybenzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C16H18N4O2, CAS 1284269-00-6
(E)-3-Cyclopropyl-N'-(2-ethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
CAS 1284269-00-6C16H18N4O2
3-Cyclopropyl-N'-[(E)-(2,6-dichlorophenyl)methylidene]-1H-pyrazole-5-carbohydrazide chemical structure, C14H12Cl2N4O, CAS 1285541-06-1
3-Cyclopropyl-N'-[(E)-(2,6-dichlorophenyl)methylidene]-1H-pyrazole-5-carbohydrazide
CAS 1285541-06-1C14H12Cl2N4O
(E)-N'-Benzylidene-3-cyclopropyl-1H-pyrazole-5-carbohydrazide chemical structure, C14H14N4O, CAS 1285537-56-5
(E)-N'-Benzylidene-3-cyclopropyl-1H-pyrazole-5-carbohydrazide
CAS 1285537-56-5C14H14N4O
(E)-3-Cyclopropyl-N'-(4-propoxybenzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C17H20N4O2, CAS 1285520-87-7
(E)-3-Cyclopropyl-N'-(4-propoxybenzylidene)-1H-pyrazole-5-carbohydrazide
CAS 1285520-87-7C17H20N4O2
(E)-3-Cyclopropyl-N'-(2-(pentyloxy)benzylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C19H24N4O2, CAS 1285614-08-5
(E)-3-Cyclopropyl-N'-(2-(pentyloxy)benzylidene)-1H-pyrazole-5-carbohydrazide
CAS 1285614-08-5C19H24N4O2
N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-5-cyclopropyl-1H-pyrazole-3-carboxamide chemical structure, C14H12ClFN4O, CAS 1359973-76-4
N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-5-cyclopropyl-1H-pyrazole-3-carboxamide
CAS 1359973-76-4C14H12ClFN4O
5-Cyclopropyl-N-(1-phenylpropylideneamino)-1H-pyrazole-3-carboxamide chemical structure, C16H18N4O, CAS 1359880-13-9
5-Cyclopropyl-N-(1-phenylpropylideneamino)-1H-pyrazole-3-carboxamide
CAS 1359880-13-9C16H18N4O
(E)-3-Cyclopropyl-N'-(1-(4-ethoxyphenyl)propylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C18H22N4O2, CAS 1048930-94-4
(E)-3-Cyclopropyl-N'-(1-(4-ethoxyphenyl)propylidene)-1H-pyrazole-5-carbohydrazide
CAS 1048930-94-4C18H22N4O2
3-Cyclopropyl-N'-[(1E)-(3-ethoxy-4-hydroxyphenyl)methylene]-1H-pyrazole-5-carbohydrazide chemical structure, C16H18N4O3, CAS 5788-38-5
3-Cyclopropyl-N'-[(1E)-(3-ethoxy-4-hydroxyphenyl)methylene]-1H-pyrazole-5-carbohydrazide
CAS 5788-38-5C16H18N4O3