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Murcko scaffold

Ring system with 3 rings and 19 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
8
With full pages
1
Scaffold SMILES

O=C(C=Cc1ccc(C2CC2)o1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc(C2CC2)o1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

(2E)-2-Cyano-3-[5-(2-methylcyclopropyl)furan-2-yl]-N-(4-nitrophenyl)prop-2-enamide chemical structure, C18H15N3O4, CAS 498568-57-3
(2E)-2-Cyano-3-[5-(2-methylcyclopropyl)furan-2-yl]-N-(4-nitrophenyl)prop-2-enamide
CAS 498568-57-3C18H15N3O4
(2E)-2-Cyano-3-[5-(2-methylcyclopropyl)furan-2-yl]-N-(3-nitrophenyl)prop-2-enamide chemical structure, C18H15N3O4, CAS 488723-37-1
(2E)-2-Cyano-3-[5-(2-methylcyclopropyl)furan-2-yl]-N-(3-nitrophenyl)prop-2-enamide
CAS 488723-37-1C18H15N3O4
(E)-2-Cyano-N-(4-methoxyphenyl)-3-[5-(2-methylcyclopropyl)furan-2-yl]prop-2-enamide chemical structure, C19H18N2O3, CAS 498570-44-8
(E)-2-Cyano-N-(4-methoxyphenyl)-3-[5-(2-methylcyclopropyl)furan-2-yl]prop-2-enamide
CAS 498570-44-8C19H18N2O3
(E)-2-Cyano-N-(2,5-dichlorophenyl)-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamide chemical structure, C18H14Cl2N2O2, CAS 1164490-92-9
(E)-2-Cyano-N-(2,5-dichlorophenyl)-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamide
CAS 1164490-92-9C18H14Cl2N2O2
(E)-2-Cyano-N-(2-methoxyphenyl)-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamide chemical structure, C19H18N2O3, CAS 489404-78-6
(E)-2-Cyano-N-(2-methoxyphenyl)-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamide
CAS 489404-78-6C19H18N2O3
(E)-2-Cyano-N-(2-fluorophenyl)-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamide chemical structure, C18H15FN2O2, CAS 496774-36-8
(E)-2-Cyano-N-(2-fluorophenyl)-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamide
CAS 496774-36-8C18H15FN2O2
(E)-Ethyl 4-(2-cyano-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamido)benzoate chemical structure, C21H20N2O4, CAS 488107-42-2
(E)-Ethyl 4-(2-cyano-3-(5-(2-methylcyclopropyl)furan-2-yl)acrylamido)benzoate
CAS 488107-42-2C21H20N2O4
4-{2-Cyano-3-[5-(2-methylcyclopropyl)furan-2-yl]prop-2-enamido}benzoic acid chemical structure, C19H16N2O4, CAS 1050896-50-8
4-{2-Cyano-3-[5-(2-methylcyclopropyl)furan-2-yl]prop-2-enamido}benzoic acid
CAS 1050896-50-8C19H16N2O4