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Murcko scaffold

2-(Piperidin-4-yl)pyridine scaffold

331 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
331
With full pages
18
Scaffold SMILES

c1ccc(C2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)pyridine page
Murcko scaffold c1ccc(C2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 289 to 331 of 331 chemicals

2-[1-(2,2,2-Trifluoroacetyl)piperidin-4-yl]pyridine-3-carboxylic acid chemical structure, C13H13F3N2O3, CAS 2680810-48-2
2-[1-(2,2,2-Trifluoroacetyl)piperidin-4-yl]pyridine-3-carboxylic acid
CAS 2680810-48-2C13H13F3N2O3
tert-Butyl 4-(6-fluoropyridin-2-yl)-4-hydroxypiperidine-1-carboxylate chemical structure, C15H21FN2O3, CAS 2680542-01-0
tert-Butyl 4-(6-fluoropyridin-2-yl)-4-hydroxypiperidine-1-carboxylate
CAS 2680542-01-0C15H21FN2O3
5-Bromo-3-nitro-2-(piperidin-4-yl)pyridine chemical structure, C10H12BrN3O2, CAS 2228707-08-0
5-Bromo-3-nitro-2-(piperidin-4-yl)pyridine
CAS 2228707-08-0C10H12BrN3O2
2-{[4-(5-Bromopyridin-2-yl)piperidin-4-yl]oxy}acetic acid chemical structure, C12H15BrN2O3, CAS 2309461-55-8
2-{[4-(5-Bromopyridin-2-yl)piperidin-4-yl]oxy}acetic acid
CAS 2309461-55-8C12H15BrN2O3
4-(6-Fluoropyridin-2-yl)-1-[(prop-2-en-1-yloxy)carbonyl]piperidine-4-carboxylic acid chemical structure, C15H17FN2O4, CAS 2763956-51-8
4-(6-Fluoropyridin-2-yl)-1-[(prop-2-en-1-yloxy)carbonyl]piperidine-4-carboxylic acid
CAS 2763956-51-8C15H17FN2O4
2-{1-[(Prop-2-en-1-yloxy)carbonyl]piperidin-4-yl}pyridine-3-carboxylic acid chemical structure, C15H18N2O4, CAS 2763954-66-9
2-{1-[(Prop-2-en-1-yloxy)carbonyl]piperidin-4-yl}pyridine-3-carboxylic acid
CAS 2763954-66-9C15H18N2O4
4-(5-Chloropyridin-2-yl)piperidine-4-carbonitrile chemical structure, C11H12ClN3, CAS 1315362-14-1
4-(5-Chloropyridin-2-yl)piperidine-4-carbonitrile
CAS 1315362-14-1C11H12ClN3
tert-Butyl 4-(6-ethynylpyridin-2-yl)piperidine-1-carboxylate chemical structure, C17H22N2O2, CAS 2819383-76-9
tert-Butyl 4-(6-ethynylpyridin-2-yl)piperidine-1-carboxylate
CAS 2819383-76-9C17H22N2O2
tert-Butyl 4-(6-bromopyridin-2-yl)-4-(methylcarbamoyl)piperidine-1-carboxylate chemical structure, C17H24BrN3O3, CAS 2814457-65-1
tert-Butyl 4-(6-bromopyridin-2-yl)-4-(methylcarbamoyl)piperidine-1-carboxylate
CAS 2814457-65-1C17H24BrN3O3
4-(6-Bromopyridin-2-yl)piperidine-4-carboxamide dihydrochloride chemical structure, C11H16BrCl2N3O, CAS 2810073-35-7
4-(6-Bromopyridin-2-yl)piperidine-4-carboxamide dihydrochloride
CAS 2810073-35-7C11H16BrCl2N3O
3-Chloro-2-(piperidin-4-yl)-5-(trifluoromethyl)pyridine chemical structure, C11H12ClF3N2, CAS 1207109-29-2
3-Chloro-2-(piperidin-4-yl)-5-(trifluoromethyl)pyridine
CAS 1207109-29-2C11H12ClF3N2
3-Ethoxy-2-(piperidin-4-yl)pyridine chemical structure, C12H18N2O, CAS 2749284-80-6
3-Ethoxy-2-(piperidin-4-yl)pyridine
CAS 2749284-80-6C12H18N2O
3-Isopropoxy-2-(piperidin-4-yl)pyridine chemical structure, C13H20N2O, CAS 2748253-76-9
3-Isopropoxy-2-(piperidin-4-yl)pyridine
CAS 2748253-76-9C13H20N2O
3-(Difluoromethoxy)-2-(piperidin-4-yl)pyridine chemical structure, C11H14F2N2O, CAS 2749749-56-0
3-(Difluoromethoxy)-2-(piperidin-4-yl)pyridine
CAS 2749749-56-0C11H14F2N2O
(6-(1-(tert-Butoxycarbonyl)piperidin-4-yl)pyridin-3-yl)boronic acid chemical structure, C15H23BN2O4, CAS 2756317-81-2
(6-(1-(tert-Butoxycarbonyl)piperidin-4-yl)pyridin-3-yl)boronic acid
CAS 2756317-81-2C15H23BN2O4
1,1-Dimethylethyl 4-[6-(aminomethyl)-2-pyridinyl]-1-piperidinecarboxylate chemical structure, C16H25N3O2, CAS 1824072-89-0
1,1-Dimethylethyl 4-[6-(aminomethyl)-2-pyridinyl]-1-piperidinecarboxylate
CAS 1824072-89-0C16H25N3O2
tert-Butyl 4-(6-bromopyridin-2-yl-3,4,5-d3)piperidine-1-carboxylate chemical structure, C15H21BrN2O2, CAS 2697155-30-7
tert-Butyl 4-(6-bromopyridin-2-yl-3,4,5-d3)piperidine-1-carboxylate
CAS 2697155-30-7C15H21BrN2O2
tert-Butyl 4-(4-bromopyridin-2-yl)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9 chemical structure, C15H21BrN2O2, CAS 2697156-78-6
tert-Butyl 4-(4-bromopyridin-2-yl)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9
CAS 2697156-78-6C15H21BrN2O2
tert-Butyl 4-(6-aminopyridin-2-yl)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9 chemical structure, C15H23N3O2, CAS 2768655-61-2
tert-Butyl 4-(6-aminopyridin-2-yl)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9
CAS 2768655-61-2C15H23N3O2
tert-Butyl 4-(4-bromopyridin-2-yl-3,5,6-d3)piperidine-1-carboxylate chemical structure, C15H21BrN2O2, CAS 2697163-06-5
tert-Butyl 4-(4-bromopyridin-2-yl-3,5,6-d3)piperidine-1-carboxylate
CAS 2697163-06-5C15H21BrN2O2
tert-Butyl 4-(5-bromopyridin-2-yl-3,4,6-d3)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9 chemical structure, C15H21BrN2O2, CAS 2697155-97-6
tert-Butyl 4-(5-bromopyridin-2-yl-3,4,6-d3)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9
CAS 2697155-97-6C15H21BrN2O2
tert-Butyl 4-(5-bromopyridin-2-yl-3,4,6-d3)piperidine-1-carboxylate chemical structure, C15H21BrN2O2, CAS 2697162-81-3
tert-Butyl 4-(5-bromopyridin-2-yl-3,4,6-d3)piperidine-1-carboxylate
CAS 2697162-81-3C15H21BrN2O2
tert-Butyl 4-(6-bromopyridin-2-yl-3,4,5-d3)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9 chemical structure, C15H21BrN2O2, CAS 2697162-47-1
tert-Butyl 4-(6-bromopyridin-2-yl-3,4,5-d3)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9
CAS 2697162-47-1C15H21BrN2O2
tert-Butyl 4-(6-bromopyridin-2-yl)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9 chemical structure, C15H21BrN2O2, CAS 2697162-48-2
tert-Butyl 4-(6-bromopyridin-2-yl)piperidine-1-carboxylate-2,2,3,3,4,5,5,6,6-d9
CAS 2697162-48-2C15H21BrN2O2