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Murcko scaffold

2-(Piperidin-4-yl)pyridine scaffold

331 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
331
With full pages
18
Scaffold SMILES

c1ccc(C2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)pyridine page
Murcko scaffold c1ccc(C2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 331 chemicals

1-Methyl-4-(pyridin-2-yl)piperidine-4-carbonitrile chemical structure, C12H15N3, CAS 50288-69-2
1-Methyl-4-(pyridin-2-yl)piperidine-4-carbonitrile
CAS 50288-69-2C12H15N3
2-(1-Methylpiperidin-4-yl)pyridine chemical structure, C11H16N2, CAS 85237-63-4
2-(1-Methylpiperidin-4-yl)pyridine
CAS 85237-63-4C11H16N2
4-Piperidinol, 1-butyl-4-(2-pyridyl)-, propionate, dihydrochloride chemical structure, C17H28Cl2N2O2, CAS 63916-41-6
4-Piperidinol, 1-butyl-4-(2-pyridyl)-, propionate, dihydrochloride
CAS 63916-41-6C17H28Cl2N2O2
4-(2-Pyridinyl)-4-piperidinol chemical structure, C10H14N2O, CAS 50461-56-8
4-(2-Pyridinyl)-4-piperidinol
CAS 50461-56-8C10H14N2O
4-(2-Pyridinyl)-1-piperidinepropanamine chemical structure, C13H21N3, CAS 189129-78-0
4-(2-Pyridinyl)-1-piperidinepropanamine
CAS 189129-78-0C13H21N3
2-(Piperidin-4-yl)pyridine chemical structure, C10H14N2, CAS 30532-37-7
2-(Piperidin-4-yl)pyridine
CAS 30532-37-7C10H14N2
2-Chloro-6-(piperidin-4-yl)pyridine chemical structure, C10H13ClN2, CAS 753436-51-0
2-Chloro-6-(piperidin-4-yl)pyridine
CAS 753436-51-0C10H13ClN2
tert-Butyl 4-(pyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H22N2O2, CAS 206446-49-3
tert-Butyl 4-(pyridin-2-yl)piperidine-1-carboxylate
CAS 206446-49-3C15H22N2O2
3-Methyl-2-(piperidin-4-yl)pyridine chemical structure, C11H16N2, CAS 821768-08-5
3-Methyl-2-(piperidin-4-yl)pyridine
CAS 821768-08-5C11H16N2
4-(6-Chloro-2-pyridinyl)-1-methyl-4-piperidinol chemical structure, C11H15ClN2O, CAS 225112-34-5
4-(6-Chloro-2-pyridinyl)-1-methyl-4-piperidinol
CAS 225112-34-5C11H15ClN2O
tert-Butyl 4-hydroxy-4-(pyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H22N2O3, CAS 90606-75-0
tert-Butyl 4-hydroxy-4-(pyridin-2-yl)piperidine-1-carboxylate
CAS 90606-75-0C15H22N2O3
Ethyl 4-(pyridin-2-yl)piperidine-1-carboxylate chemical structure, C13H18N2O2, CAS 138828-90-7
Ethyl 4-(pyridin-2-yl)piperidine-1-carboxylate
CAS 138828-90-7C13H18N2O2
1-(tert-Butoxycarbonyl)-4-(5-methyl-2-pyridinyl)piperidine-4-carboxylic acid methyl ester chemical structure, C18H26N2O4, CAS 928050-20-8
1-(tert-Butoxycarbonyl)-4-(5-methyl-2-pyridinyl)piperidine-4-carboxylic acid methyl ester
CAS 928050-20-8C18H26N2O4
2-(Piperidin-4-yl)nicotinonitrile chemical structure, C11H13N3, CAS 630116-81-3
2-(Piperidin-4-yl)nicotinonitrile
CAS 630116-81-3C11H13N3
2-(Piperidin-4-yl)pyridine dihydrochloride chemical structure, C10H16Cl2N2, CAS 143924-45-2
2-(Piperidin-4-yl)pyridine dihydrochloride
CAS 143924-45-2C10H16Cl2N2
tert-Butyl 4-(6-bromopyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H21BrN2O2, CAS 939960-51-7
tert-Butyl 4-(6-bromopyridin-2-yl)piperidine-1-carboxylate
CAS 939960-51-7C15H21BrN2O2
2-(Piperidin-4-yl)-4-(trifluoromethyl)pyridine chemical structure, C11H13F3N2, CAS 1211522-22-3
2-(Piperidin-4-yl)-4-(trifluoromethyl)pyridine
CAS 1211522-22-3C11H13F3N2
6-(1-Methylpiperidin-4-yl)pyridin-2-amine chemical structure, C11H17N3, CAS 478366-36-8
6-(1-Methylpiperidin-4-yl)pyridin-2-amine
CAS 478366-36-8C11H17N3
4-(6-Bromo-2-pyridinyl)-1-methyl-4-piperidinol chemical structure, C11H15BrN2O, CAS 478366-33-5
4-(6-Bromo-2-pyridinyl)-1-methyl-4-piperidinol
CAS 478366-33-5C11H15BrN2O
4-(5-Fluoropyridin-2-yl)piperidin-4-ol chemical structure, C10H13FN2O, CAS 1207865-17-5
4-(5-Fluoropyridin-2-yl)piperidin-4-ol
CAS 1207865-17-5C10H13FN2O
4-(Pyridin-2-yl)piperidin-4-ol dihydrochloride chemical structure, C10H16Cl2N2O, CAS 172734-32-6
4-(Pyridin-2-yl)piperidin-4-ol dihydrochloride
CAS 172734-32-6C10H16Cl2N2O
tert-Butyl 4-(5-bromopyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H21BrN2O2, CAS 622387-27-3
tert-Butyl 4-(5-bromopyridin-2-yl)piperidine-1-carboxylate
CAS 622387-27-3C15H21BrN2O2
1-(3-Aminopropyl)-4-pyridin-2-ylpiperidine-4-carbonitrile chemical structure, C14H20N4, CAS 265986-07-0
1-(3-Aminopropyl)-4-pyridin-2-ylpiperidine-4-carbonitrile
CAS 265986-07-0C14H20N4
Propanamide, 2-methyl-N-[6-(4-piperidinyl)-2-pyridinyl]- chemical structure, C14H21N3O, CAS 487057-93-2
Propanamide, 2-methyl-N-[6-(4-piperidinyl)-2-pyridinyl]-
CAS 487057-93-2C14H21N3O