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Murcko scaffold

2-(Piperidin-4-yl)pyridine scaffold

331 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
331
With full pages
18
Scaffold SMILES

c1ccc(C2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)pyridine page
Murcko scaffold c1ccc(C2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 331 chemicals

1,1-Dimethylethyl 4-(5-fluoro-1-oxido-2-pyridinyl)-1-piperidinecarboxylate chemical structure, C15H21FN2O3, CAS 2230200-34-5
1,1-Dimethylethyl 4-(5-fluoro-1-oxido-2-pyridinyl)-1-piperidinecarboxylate
CAS 2230200-34-5C15H21FN2O3
2-Chloro-6-(4-piperidyl)pyridine Hydrochloride chemical structure, C10H14Cl2N2, CAS 252230-88-9
2-Chloro-6-(4-piperidyl)pyridine Hydrochloride
CAS 252230-88-9C10H14Cl2N2
1-Boc-4-(6-chloro-2-pyridyl)piperidine-4-carboxylic Acid chemical structure, C16H21ClN2O4, CAS 2230200-27-6
1-Boc-4-(6-chloro-2-pyridyl)piperidine-4-carboxylic Acid
CAS 2230200-27-6C16H21ClN2O4
Ethyl 2-[4-(6-Chloro-2-pyridyl)-1-piperidyl]acetate chemical structure, C14H19ClN2O2, CAS 2230213-35-9
Ethyl 2-[4-(6-Chloro-2-pyridyl)-1-piperidyl]acetate
CAS 2230213-35-9C14H19ClN2O2
tert-Butyl 4-formyl-4-(pyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H22N2O3, CAS 2243970-47-8
tert-Butyl 4-formyl-4-(pyridin-2-yl)piperidine-1-carboxylate
CAS 2243970-47-8C16H22N2O3
5-Chloro-2-(piperidin-4-yl)pyridine dihydrochloride chemical structure, C10H15Cl3N2, CAS 2089257-42-9
5-Chloro-2-(piperidin-4-yl)pyridine dihydrochloride
CAS 2089257-42-9C10H15Cl3N2
(6-(Piperidin-4-yl)pyridin-2-yl)methanol dihydrochloride chemical structure, C11H18Cl2N2O, CAS 2244088-81-9
(6-(Piperidin-4-yl)pyridin-2-yl)methanol dihydrochloride
CAS 2244088-81-9C11H18Cl2N2O
tert-Butyl 4-(3-cyanopyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H21N3O2, CAS 2303565-68-4
tert-Butyl 4-(3-cyanopyridin-2-yl)piperidine-1-carboxylate
CAS 2303565-68-4C16H21N3O2
5-Methoxy-6-(1-methyl-4-piperidinyl)-3-pyridinamine chemical structure, C12H19N3O, CAS 2306851-61-4
5-Methoxy-6-(1-methyl-4-piperidinyl)-3-pyridinamine
CAS 2306851-61-4C12H19N3O
tert-Butyl 4-(5-amino-3-fluoropyridin-2-yl)piperidine-1-carboxylate chemical structure, C15H22FN3O2, CAS 2351275-60-8
tert-Butyl 4-(5-amino-3-fluoropyridin-2-yl)piperidine-1-carboxylate
CAS 2351275-60-8C15H22FN3O2
4-(3-Fluoro-2-pyridinyl)piperidin-4-ol, hydrochloride chemical structure, C10H14ClFN2O, CAS 1239205-64-1
4-(3-Fluoro-2-pyridinyl)piperidin-4-ol, hydrochloride
CAS 1239205-64-1C10H14ClFN2O
1-(2-Chloropropanoyl)-4-pyridin-2-ylpiperidine-4-carbonitrile chemical structure, C14H16ClN3O, CAS 2411314-88-8
1-(2-Chloropropanoyl)-4-pyridin-2-ylpiperidine-4-carbonitrile
CAS 2411314-88-8C14H16ClN3O
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}pyridine-3-carboxylic acid chemical structure, C16H22N2O4, CAS 2386442-99-3
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}pyridine-3-carboxylic acid
CAS 2386442-99-3C16H22N2O4
1-Boc-4-(6-chloro-2-pyridyl)piperidin-4-ol chemical structure, C15H21ClN2O3, CAS 2762503-54-6
1-Boc-4-(6-chloro-2-pyridyl)piperidin-4-ol
CAS 2762503-54-6C15H21ClN2O3
1-(tert-Butyl) 4-ethyl 4-(3-methylpyridin-2-yl)piperidine-1,4-dicarboxylate chemical structure, C19H28N2O4, CAS 2245085-48-5
1-(tert-Butyl) 4-ethyl 4-(3-methylpyridin-2-yl)piperidine-1,4-dicarboxylate
CAS 2245085-48-5C19H28N2O4
tert-Butyl 4-(5-amino-6-methoxypyridin-2-yl)piperidine-1-carboxylate chemical structure, C16H25N3O3, CAS 2446914-53-8
tert-Butyl 4-(5-amino-6-methoxypyridin-2-yl)piperidine-1-carboxylate
CAS 2446914-53-8C16H25N3O3
2-(Piperidin-4-yl)-5-(trifluoromethyl)pyridine dihydrochloride chemical structure, C11H15Cl2F3N2, CAS 2401787-79-7
2-(Piperidin-4-yl)-5-(trifluoromethyl)pyridine dihydrochloride
CAS 2401787-79-7C11H15Cl2F3N2
5-Bromo-2-(piperidin-4-yl)pyridine dihydrochloride chemical structure, C10H15BrCl2N2, CAS 2418731-98-1
5-Bromo-2-(piperidin-4-yl)pyridine dihydrochloride
CAS 2418731-98-1C10H15BrCl2N2
2_(1_Methylpiperidin_4_yl)pyridine_3,4_diamine chemical structure, C11H18N4, CAS 2454173-04-5
2_(1_Methylpiperidin_4_yl)pyridine_3,4_diamine
CAS 2454173-04-5C11H18N4
6-(Piperidin-4-yl)pyridin-3-amine hydrochloride chemical structure, C10H16ClN3, CAS 845788-64-9
6-(Piperidin-4-yl)pyridin-3-amine hydrochloride
CAS 845788-64-9C10H16ClN3
2-(Piperidin-4-yl)pyridin-4-amine dihydrochloride chemical structure, C10H17Cl2N3, CAS 2470434-97-8
2-(Piperidin-4-yl)pyridin-4-amine dihydrochloride
CAS 2470434-97-8C10H17Cl2N3
tert-Butyl 4-(3-bromo-5-fluoropyridin-2-yl)-4-cyanopiperidine-1-carboxylate chemical structure, C16H19BrFN3O2, CAS 2573798-23-7
tert-Butyl 4-(3-bromo-5-fluoropyridin-2-yl)-4-cyanopiperidine-1-carboxylate
CAS 2573798-23-7C16H19BrFN3O2
1-[(tert-Butoxy)carbonyl]-4-(6-fluoropyridin-2-yl)piperidine-4-carboxylic acid chemical structure, C16H21FN2O4, CAS 2357831-08-2
1-[(tert-Butoxy)carbonyl]-4-(6-fluoropyridin-2-yl)piperidine-4-carboxylic acid
CAS 2357831-08-2C16H21FN2O4
3-Amino-6-piperidin-4-ylpyridine-2-carboxamide, dihydrochloride chemical structure, C11H18Cl2N4O, CAS 2490402-42-9
3-Amino-6-piperidin-4-ylpyridine-2-carboxamide, dihydrochloride
CAS 2490402-42-9C11H18Cl2N4O