Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 18 atoms

19 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 19
With full pages: 4

Scaffold SMILES

O=C(Nc1cc2c(s1)CCCC2)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1cc2c(s1)CCCC2)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

Methyl 6-tert-butyl-2-[(pyridin-3-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C20H24N2O3S, CAS 419559-71-0

Methyl 6-tert-butyl-2-[(pyridin-3-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 419559-71-0C₂₀H₂₄N₂O₃S

Methyl 2-[(3-pyridinylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C16H16N2O3S, CAS 301694-34-8

Methyl 2-[(3-pyridinylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 301694-34-8C₁₆H₁₆N₂O₃S

Ethyl 4,5,6,7-tetrahydro-2-((3-pyridinylcarbonyl)amino)benzo(b)thiophene-3-carboxylate chemical structure, C17H18N2O3S, CAS 62349-06-8

Ethyl 4,5,6,7-tetrahydro-2-((3-pyridinylcarbonyl)amino)benzo(b)thiophene-3-carboxylate

CAS 62349-06-8C₁₇H₁₈N₂O₃S

N-(3-Carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)nicotinamide chemical structure, C15H15N3O2S, CAS 298207-49-5

N-(3-Carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)nicotinamide

CAS 298207-49-5C₁₅H₁₅N₃O₂S

N-(3-Cyano-4,5,6,7-tetrahydrobenzo(b)thien-2-yl)-3-pyridinecarboxamide chemical structure, C15H13N3OS, CAS 303793-48-8

N-(3-Cyano-4,5,6,7-tetrahydrobenzo(b)thien-2-yl)-3-pyridinecarboxamide

CAS 303793-48-8C₁₅H₁₃N₃OS

5-Bromo-N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide chemical structure, C15H14BrN3O2S, CAS 303031-50-7

5-Bromo-N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide

CAS 303031-50-7C₁₅H₁₄BrN₃O₂S

Ethyl 2-{[(2-chloropyridin-3-yl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C17H17ClN2O3S, CAS 350698-63-4

Ethyl 2-{[(2-chloropyridin-3-yl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 350698-63-4C₁₇H₁₇ClN₂O₃S

Methyl 2-{[(5-bromopyridin-3-yl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C16H15BrN2O3S, CAS 303031-52-9

Methyl 2-{[(5-bromopyridin-3-yl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 303031-52-9C₁₆H₁₅BrN₂O₃S

2-(Pyridine-3-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid chemical structure, C15H14N2O3S, CAS 314032-09-2

2-(Pyridine-3-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

CAS 314032-09-2C₁₅H₁₄N₂O₃S

Propyl 2-[(3-pyridinylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C18H20N2O3S, CAS 550305-42-5

Propyl 2-[(3-pyridinylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 550305-42-5C₁₈H₂₀N₂O₃S

Ethyl 6-methyl-2-(pyridine-3-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C18H20N2O3S, CAS 302573-84-8

Ethyl 6-methyl-2-(pyridine-3-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 302573-84-8C₁₈H₂₀N₂O₃S

Ethyl 2-{[(5-bromopyridin-3-yl)carbonyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C18H19BrN2O3S, CAS 370850-60-5

Ethyl 2-{[(5-bromopyridin-3-yl)carbonyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 370850-60-5C₁₈H₁₉BrN₂O₃S

Methyl 2-{[(5-bromopyridin-3-yl)carbonyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C17H17BrN2O3S, CAS 303031-54-1

Methyl 2-{[(5-bromopyridin-3-yl)carbonyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

CAS 303031-54-1C₁₇H₁₇BrN₂O₃S

5-Bromo-N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide chemical structure, C16H16BrN3O2S, CAS 303031-57-4

5-Bromo-N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide

CAS 303031-57-4C₁₆H₁₆BrN₃O₂S

N-(3-Cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide chemical structure, C16H15N3OS, CAS 4109-40-4

N-(3-Cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide

CAS 4109-40-4C₁₆H₁₅N₃OS

N-(3-Carbamoyl-6-ethyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide chemical structure, C17H19N3O2S, CAS 353478-63-4

N-(3-Carbamoyl-6-ethyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide

CAS 353478-63-4C₁₇H₁₉N₃O₂S

N-(3-Carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C16H17N3O2S2, CAS 877967-11-8

N-(3-Carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(methylsulfanyl)pyridine-3-carboxamide

CAS 877967-11-8C₁₆H₁₇N₃O₂S₂

N-(3-Carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C17H19N3O2S2, CAS 878116-45-1

N-(3-Carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(methylsulfanyl)pyridine-3-carboxamide

CAS 878116-45-1C₁₇H₁₉N₃O₂S₂

N-(3-Carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5,6-dichloropyridine-3-carboxamide chemical structure, C16H15Cl2N3O2S, CAS 924186-75-4

N-(3-Carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5,6-dichloropyridine-3-carboxamide

CAS 924186-75-4C₁₆H₁₅Cl₂N₃O₂S