CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 14 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
10
With full pages
4
Scaffold SMILES

c1ccc(CSCc2nncs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSCc2nncs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

5-Benzylsulfanylmethyl-[1,3,4]thiadiazol-2-ylamine chemical structure, C10H11N3S2, CAS 247225-83-8
5-Benzylsulfanylmethyl-[1,3,4]thiadiazol-2-ylamine
CAS 247225-83-8C10H11N3S2
5-{[(4-Fluorobenzyl)thio]methyl}-1,3,4-thiadiazol-2-amine chemical structure, C10H10FN3S2, CAS 292064-75-6
5-{[(4-Fluorobenzyl)thio]methyl}-1,3,4-thiadiazol-2-amine
CAS 292064-75-6C10H10FN3S2
5-{[(3-Methylbenzyl)sulfanyl]methyl}-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3S2, CAS 299443-05-3
5-{[(3-Methylbenzyl)sulfanyl]methyl}-1,3,4-thiadiazol-2-amine
CAS 299443-05-3C11H13N3S2
5-{[(4-Chlorobenzyl)sulfanyl]methyl}-1,3,4-thiadiazol-2-amine chemical structure, C10H10ClN3S2, CAS 299934-12-6
5-{[(4-Chlorobenzyl)sulfanyl]methyl}-1,3,4-thiadiazol-2-amine
CAS 299934-12-6C10H10ClN3S2
N-[5-[(4-Fluorophenyl)methylsulfanylmethyl]-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C13H14FN3OS2, CAS 767346-68-9
N-[5-[(4-Fluorophenyl)methylsulfanylmethyl]-1,3,4-thiadiazol-2-yl]propanamide
CAS 767346-68-9C13H14FN3OS2
5-(((3-Bromobenzyl)thio)methyl)-1,3,4-thiadiazol-2-amine chemical structure, C10H10BrN3S2, CAS 400739-75-5
5-(((3-Bromobenzyl)thio)methyl)-1,3,4-thiadiazol-2-amine
CAS 400739-75-5C10H10BrN3S2
Methyl (5-(((3-bromobenzyl)thio)methyl)-1,3,4-thiadiazol-2-yl)carbamate chemical structure, C12H12BrN3O2S2, CAS 695160-49-7
Methyl (5-(((3-bromobenzyl)thio)methyl)-1,3,4-thiadiazol-2-yl)carbamate
CAS 695160-49-7C12H12BrN3O2S2
N-[5-(Benzylsulfanylmethyl)-1,3,4-thiadiazol-2-yl]-3,3-dimethylbutanamide chemical structure, C16H21N3OS2, CAS 879595-03-6
N-[5-(Benzylsulfanylmethyl)-1,3,4-thiadiazol-2-yl]-3,3-dimethylbutanamide
CAS 879595-03-6C16H21N3OS2
N-[5-(Benzylsulfanylmethyl)-1,3,4-thiadiazol-2-yl]-2-methoxyacetamide chemical structure, C13H15N3O2S2, CAS 892672-84-3
N-[5-(Benzylsulfanylmethyl)-1,3,4-thiadiazol-2-yl]-2-methoxyacetamide
CAS 892672-84-3C13H15N3O2S2
N-[5-(Benzylsulfanylmethyl)-1,3,4-thiadiazol-2-yl]methanesulfonamide chemical structure, C11H13N3O2S3, CAS 892675-13-7
N-[5-(Benzylsulfanylmethyl)-1,3,4-thiadiazol-2-yl]methanesulfonamide
CAS 892675-13-7C11H13N3O2S3