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Murcko scaffold

Ring system with 2 rings and 12 atoms

25 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
25
With full pages
4
Scaffold SMILES

O=C1CCCC(c2ccn[nH]2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC(c2ccn[nH]2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1820583-61-6
(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid
CAS 1820583-61-6C11H15N3O3
rac-(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1807939-93-0
rac-(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid
CAS 1807939-93-0C11H15N3O3
1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1715182-13-0
1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid
CAS 1715182-13-0C11H15N3O3
1-Ethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1772117-23-3
1-Ethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid
CAS 1772117-23-3C12H17N3O3
5-Amino-1-methyl-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one chemical structure, C10H16N4O, CAS 1602231-99-1
5-Amino-1-methyl-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one
CAS 1602231-99-1C10H16N4O
5-Amino-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one chemical structure, C9H14N4O, CAS 1592709-22-2
5-Amino-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one
CAS 1592709-22-2C9H14N4O
5-Amino-6-(1-ethyl-1H-pyrazol-5-yl)piperidin-2-one chemical structure, C10H16N4O, CAS 1601078-84-5
5-Amino-6-(1-ethyl-1H-pyrazol-5-yl)piperidin-2-one
CAS 1601078-84-5C10H16N4O
rac-(5R,6R)-5-Amino-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one chemical structure, C9H14N4O, CAS 2307778-06-7
rac-(5R,6R)-5-Amino-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one
CAS 2307778-06-7C9H14N4O
(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide chemical structure, C11H16N4O2, CAS 1820575-87-8
(2R,3R)-1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide
CAS 1820575-87-8C11H16N4O2
Methyl (2R,3R)-1-methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylate chemical structure, C12H17N3O3, CAS 1820574-72-8
Methyl (2R,3R)-1-methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylate
CAS 1820574-72-8C12H17N3O3
(2R,3R)-N,1-Dimethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide chemical structure, C12H18N4O2, CAS 1820576-17-7
(2R,3R)-N,1-Dimethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide
CAS 1820576-17-7C12H18N4O2
(5R,6R)-5-Amino-1-methyl-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one chemical structure, C10H16N4O, CAS 1820580-56-0
(5R,6R)-5-Amino-1-methyl-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one
CAS 1820580-56-0C10H16N4O
N-[(2R,3R)-2-(2-Methylpyrazol-3-yl)-6-oxopiperidin-3-yl]prop-2-enamide chemical structure, C12H16N4O2, CAS 2411181-29-6
N-[(2R,3R)-2-(2-Methylpyrazol-3-yl)-6-oxopiperidin-3-yl]prop-2-enamide
CAS 2411181-29-6C12H16N4O2
rac-(5R,6R)-5-Amino-6-[1-(propan-2-yl)-1H-pyrazol-5-yl]piperidin-2-one chemical structure, C11H18N4O, CAS 1969287-65-7
rac-(5R,6R)-5-Amino-6-[1-(propan-2-yl)-1H-pyrazol-5-yl]piperidin-2-one
CAS 1969287-65-7C11H18N4O
rac-(2R,3R)-1-Ethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 1955530-49-0
rac-(2R,3R)-1-Ethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylic acid
CAS 1955530-49-0C12H17N3O3
6-(1-Methyl-1H-pyrazol-5-yl)-5-nitropiperidin-2-one chemical structure, C9H12N4O3, CAS 1803561-76-3
6-(1-Methyl-1H-pyrazol-5-yl)-5-nitropiperidin-2-one
CAS 1803561-76-3C9H12N4O3
5-Nitro-6-(1H-pyrazol-3-yl)piperidin-2-one chemical structure, C8H10N4O3, CAS 1803598-38-0
5-Nitro-6-(1H-pyrazol-3-yl)piperidin-2-one
CAS 1803598-38-0C8H10N4O3
N,1-Dimethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide chemical structure, C12H18N4O2, CAS 1955520-66-7
N,1-Dimethyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide
CAS 1955520-66-7C12H18N4O2
1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide chemical structure, C11H16N4O2, CAS 1955560-90-3
1-Methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxamide
CAS 1955560-90-3C11H16N4O2
Methyl 1-methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylate chemical structure, C12H17N3O3, CAS 1955494-67-3
Methyl 1-methyl-2-(1-methyl-1H-pyrazol-5-yl)-6-oxopiperidine-3-carboxylate
CAS 1955494-67-3C12H17N3O3
Rac-(5R,6R)-5-amino-1-methyl-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one chemical structure, C10H16N4O, CAS 2137739-09-2
Rac-(5R,6R)-5-amino-1-methyl-6-(1-methyl-1H-pyrazol-5-yl)piperidin-2-one
CAS 2137739-09-2C10H16N4O
(2S,3S)-1-Methyl-2-(2-methylpyrazol-3-yl)-6-oxopiperidine-3-carboxamide chemical structure, C11H16N4O2, CAS 1807939-61-2
(2S,3S)-1-Methyl-2-(2-methylpyrazol-3-yl)-6-oxopiperidine-3-carboxamide
CAS 1807939-61-2C11H16N4O2
N-[2-(2-Ethylpyrazol-3-yl)-6-oxopiperidin-3-yl]prop-2-enamide chemical structure, C13H18N4O2, CAS 2305278-05-9
N-[2-(2-Ethylpyrazol-3-yl)-6-oxopiperidin-3-yl]prop-2-enamide
CAS 2305278-05-9C13H18N4O2
5-Amino-6-[1-(propan-2-yl)-1H-pyrazol-5-yl]piperidin-2-one chemical structure, C11H18N4O, CAS 2026076-07-1
5-Amino-6-[1-(propan-2-yl)-1H-pyrazol-5-yl]piperidin-2-one
CAS 2026076-07-1C11H18N4O