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Murcko scaffold

N-Benzylpyrazine-2-carboxamide scaffold

55 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 16
Chemicals: 55
With full pages: 3

Scaffold SMILES

O=C(NCc1ccccc1)c1cnccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-Benzylpyrazine-2-carboxamide page

Murcko scaffold O=C(NCc1ccccc1)c1cnccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

N-Benzyl-5-chloropyrazine-2-carboxamide chemical structure, C12H10ClN3O, CAS 958799-53-6

N-Benzyl-5-chloropyrazine-2-carboxamide

CAS 958799-53-6C₁₂H₁₀ClN₃O

N-Benzylpyrazine-2-carboxamide chemical structure, C12H11N3O, CAS 347368-07-4

N-Benzylpyrazine-2-carboxamide

CAS 347368-07-4C₁₂H₁₁N₃O

N-(2,4-Dimethoxybenzyl)-5-methylpyrazine-2-carboxamide chemical structure, C15H17N3O3, CAS 606132-21-2

N-(2,4-Dimethoxybenzyl)-5-methylpyrazine-2-carboxamide

CAS 606132-21-2C₁₅H₁₇N₃O₃

N-(3-(Trifluoromethyl)benzyl)pyrazine-2-carboxamide chemical structure, C13H10F3N3O, CAS 606132-12-1

N-(3-(Trifluoromethyl)benzyl)pyrazine-2-carboxamide

CAS 606132-12-1C₁₃H₁₀F₃N₃O

N-(2,4-Dimethoxybenzyl)pyrazine-2-carboxamide chemical structure, C14H15N3O3, CAS 606132-14-3

N-(2,4-Dimethoxybenzyl)pyrazine-2-carboxamide

CAS 606132-14-3C₁₄H₁₅N₃O₃

N-[(2,4-Dichlorophenyl)methyl]-5-methylpyrazine-2-carboxamide chemical structure, C13H11Cl2N3O, CAS 729564-09-4

N-[(2,4-Dichlorophenyl)methyl]-5-methylpyrazine-2-carboxamide

CAS 729564-09-4C₁₃H₁₁Cl₂N₃O

3-(((4-Fluorophenyl)methyl)carbamoyl)pyrazine-2-carboxylic acid chemical structure, C13H10FN3O3, CAS 730242-83-8

3-(((4-Fluorophenyl)methyl)carbamoyl)pyrazine-2-carboxylic acid

CAS 730242-83-8C₁₃H₁₀FN₃O₃

N-(3,4-Dichlorobenzyl)-N-methylpyrazine-2-carboxamide chemical structure, C13H11Cl2N3O, CAS 851287-79-1

N-(3,4-Dichlorobenzyl)-N-methylpyrazine-2-carboxamide

CAS 851287-79-1C₁₃H₁₁Cl₂N₃O

N-(1-Phenylethyl)pyrazine-2-carboxamide chemical structure, C13H13N3O, CAS 352705-14-7

N-(1-Phenylethyl)pyrazine-2-carboxamide

CAS 352705-14-7C₁₃H₁₃N₃O

N-[1-(4-Methylphenyl)propyl]pyrazine-2-carboxamide chemical structure, C15H17N3O, CAS 524933-93-5

N-[1-(4-Methylphenyl)propyl]pyrazine-2-carboxamide

CAS 524933-93-5C₁₅H₁₇N₃O

N-(3,4-Dichlorobenzyl)pyrazine-2-carboxamide chemical structure, C12H9Cl2N3O, CAS 544679-09-6

N-(3,4-Dichlorobenzyl)pyrazine-2-carboxamide

CAS 544679-09-6C₁₂H₉Cl₂N₃O

3-Amino-N-benzylpyrazine-2-carboxamide chemical structure, C12H12N4O, CAS 22908-04-9

3-Amino-N-benzylpyrazine-2-carboxamide

CAS 22908-04-9C₁₂H₁₂N₄O

3-Amino-N-benzyl-N-methylpyrazine-2-carboxamide chemical structure, C13H14N4O, CAS 930713-21-6

3-Amino-N-benzyl-N-methylpyrazine-2-carboxamide

CAS 930713-21-6C₁₃H₁₄N₄O

3-Amino-N-(4-methoxybenzyl)pyrazine-2-carboxamide chemical structure, C13H14N4O2, CAS 221539-34-0

3-Amino-N-(4-methoxybenzyl)pyrazine-2-carboxamide

CAS 221539-34-0C₁₃H₁₄N₄O₂

N-Benzyl-N-methylpyrazine-2-carboxamide chemical structure, C13H13N3O, CAS 854697-82-8

N-Benzyl-N-methylpyrazine-2-carboxamide

CAS 854697-82-8C₁₃H₁₃N₃O

N-(1-(2,4-Dichlorophenyl)ethyl)pyrazine-2-carboxamide chemical structure, C13H11Cl2N3O, CAS 1182049-77-9

N-(1-(2,4-Dichlorophenyl)ethyl)pyrazine-2-carboxamide

CAS 1182049-77-9C₁₃H₁₁Cl₂N₃O

2-Chloro-beta-[[(5-methyl-2-pyrazinyl)carbonyl]amino]benzenepropanoic acid chemical structure, C15H14ClN3O3, CAS 1210477-98-7

2-Chloro-beta-[[(5-methyl-2-pyrazinyl)carbonyl]amino]benzenepropanoic acid

CAS 1210477-98-7C₁₅H₁₄ClN₃O₃

N-(2,6-Difluorobenzyl)-5-methylpyrazine-2-carboxamide chemical structure, C13H11F2N3O, CAS 1235142-13-8

N-(2,6-Difluorobenzyl)-5-methylpyrazine-2-carboxamide

CAS 1235142-13-8C₁₃H₁₁F₂N₃O

3-Amino-N-(4-fluorobenzyl)pyrazine-2-carboxamide chemical structure, C12H11FN4O, CAS 1190015-09-8

3-Amino-N-(4-fluorobenzyl)pyrazine-2-carboxamide

CAS 1190015-09-8C₁₂H₁₁FN₄O

3-(2-Chlorophenyl)-3-[(pyrazin-2-yl)formamido]propanoic acid chemical structure, C14H12ClN3O3, CAS 1222970-08-2

3-(2-Chlorophenyl)-3-[(pyrazin-2-yl)formamido]propanoic acid

CAS 1222970-08-2C₁₄H₁₂ClN₃O₃

6-Chloro-N-(2-methylbenzyl)pyrazine-2-carboxamide chemical structure, C13H12ClN3O, CAS 1194687-48-3

6-Chloro-N-(2-methylbenzyl)pyrazine-2-carboxamide

CAS 1194687-48-3C₁₃H₁₂ClN₃O

(S)-3-Amino-6-cyano-N-(1-(3,4-difluorophenyl)ethyl)pyrazine-2-carboxamide chemical structure, C14H11F2N5O, CAS 1289189-06-5

(S)-3-Amino-6-cyano-N-(1-(3,4-difluorophenyl)ethyl)pyrazine-2-carboxamide

CAS 1289189-06-5C₁₄H₁₁F₂N₅O

5-Chloro-N-(2-chlorobenzyl)pyrazine-2-carboxamide chemical structure, C12H9Cl2N3O, CAS 1438853-89-4

5-Chloro-N-(2-chlorobenzyl)pyrazine-2-carboxamide

CAS 1438853-89-4C₁₂H₉Cl₂N₃O

5-Chloro-N-(3-chlorobenzyl)pyrazine-2-carboxamide chemical structure, C12H9Cl2N3O, CAS 1438853-90-7

5-Chloro-N-(3-chlorobenzyl)pyrazine-2-carboxamide

CAS 1438853-90-7C₁₂H₉Cl₂N₃O