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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 2,195 chemicals

Pyrazophos chemical structure, C14H20N3O5PS, CAS 13457-18-6
Pyrazophos
CAS 13457-18-6C14H20N3O5PS
AI 3-27607 chemical structure, C12H17BrN3O3PS, CAS 7682-90-8
AI 3-27607
CAS 7682-90-8C12H17BrN3O3PS
AI 3-27608 chemical structure, C12H17ClN3O3PS, CAS 32575-80-7
AI 3-27608
CAS 32575-80-7C12H17ClN3O3PS
3-Bromo-5,7-dimethylpyrazolo(1,5-a)pyrimidine chemical structure, C8H8BrN3, CAS 41945-37-3
3-Bromo-5,7-dimethylpyrazolo(1,5-a)pyrimidine
CAS 41945-37-3C8H8BrN3
Pyrazolo(1,5-a)pyrimidine, 3-chloro-5,7-dimethyl- chemical structure, C8H8ClN3, CAS 43024-25-5
Pyrazolo(1,5-a)pyrimidine, 3-chloro-5,7-dimethyl-
CAS 43024-25-5C8H8ClN3
Pyrazolo(1.5-a)pyrimidine, 5,7-dimethyl-3-iodo- chemical structure, C8H8IN3, CAS 43024-26-6
Pyrazolo(1.5-a)pyrimidine, 5,7-dimethyl-3-iodo-
CAS 43024-26-6C8H8IN3
Pyrazolo(1,5-a)pyrimidine, 5,7-dimethyl- chemical structure, C8H9N3, CAS 35149-38-3
Pyrazolo(1,5-a)pyrimidine, 5,7-dimethyl-
CAS 35149-38-3C8H9N3
2-(Cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C11H9N5, CAS 5466-67-1
2-(Cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 5466-67-1C11H9N5
6-Nitropyrazolo[1,5-a]pyrimidine chemical structure, C6H4N4O2, CAS 55405-65-7
6-Nitropyrazolo[1,5-a]pyrimidine
CAS 55405-65-7C6H4N4O2
Ethyl 6-acetyl-3-cyanopyrazolo[1,5-a]pyrimidine-7-carboxylate chemical structure, C12H10N4O3, CAS 70169-91-4
Ethyl 6-acetyl-3-cyanopyrazolo[1,5-a]pyrimidine-7-carboxylate
CAS 70169-91-4C12H10N4O3
2-(tert-Butyl)-3,7-dichloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C11H10Cl2F3N3, CAS 655235-54-4
2-(tert-Butyl)-3,7-dichloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 655235-54-4C11H10Cl2F3N3
2,5-Dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H7F3N4, CAS 767323-10-4
2,5-Dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 767323-10-4C10H7F3N4
6-Aminopyrazolo[1,5-a]pyrimidine-7-carbonitrile chemical structure, C7H5N5, CAS 959106-15-1
6-Aminopyrazolo[1,5-a]pyrimidine-7-carbonitrile
CAS 959106-15-1C7H5N5
5-Methyl-3-nitro-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C8H5F3N4O2, CAS 296796-64-0
5-Methyl-3-nitro-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 296796-64-0C8H5F3N4O2
Ethyl (3-cyano-2,5,7-trimethylpyrazolo[1,5-a]pyrimidin-6-yl)acetate chemical structure, C14H16N4O2, CAS 447410-30-2
Ethyl (3-cyano-2,5,7-trimethylpyrazolo[1,5-a]pyrimidin-6-yl)acetate
CAS 447410-30-2C14H16N4O2
5,7-Dimethyl-2-(methylsulfanyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H10N4S, CAS 90842-90-3
5,7-Dimethyl-2-(methylsulfanyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 90842-90-3C10H10N4S
6-Bromopyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C7H3BrN4, CAS 352637-44-6
6-Bromopyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 352637-44-6C7H3BrN4
6-Acetyl-7-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile chemical structure, C10H8N4O, CAS 83702-52-7
6-Acetyl-7-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile
CAS 83702-52-7C10H8N4O
1-(2,7-Dimethylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone chemical structure, C10H11N3O, CAS 130506-85-3
1-(2,7-Dimethylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone
CAS 130506-85-3C10H11N3O
1-(7-Methylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone chemical structure, C9H9N3O, CAS 130506-80-8
1-(7-Methylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone
CAS 130506-80-8C9H9N3O
2,5,7-Trimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H10N4, CAS 146778-12-3
2,5,7-Trimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 146778-12-3C10H10N4
Ethyl 7-methyl-3-nitropyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C10H10N4O4, CAS 329207-51-4
Ethyl 7-methyl-3-nitropyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 329207-51-4C10H10N4O4
7-Methyl-3-nitropyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C8H6N4O4, CAS 329207-52-5
7-Methyl-3-nitropyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 329207-52-5C8H6N4O4
6-Nitropyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C7H3N5O2, CAS 80772-97-0
6-Nitropyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 80772-97-0C7H3N5O2