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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,873 to 1,920 of 2,195 chemicals

7-Ethyl-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H10N4, CAS 2137519-01-6
7-Ethyl-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 2137519-01-6C10H10N4
5-(Difluoromethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C9H6F2N4, CAS 2137854-65-8
5-(Difluoromethyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 2137854-65-8C9H6F2N4
tert-Butyl N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-yl)carbamate chemical structure, C14H18N4O3, CAS 2229180-61-2
tert-Butyl N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-yl)carbamate
CAS 2229180-61-2C14H18N4O3
3-Bromo-6-methanesulfonylpyrazolo(1,5-a)pyrimidine chemical structure, C7H6BrN3O2S, CAS 2758005-56-8
3-Bromo-6-methanesulfonylpyrazolo(1,5-a)pyrimidine
CAS 2758005-56-8C7H6BrN3O2S
6-(2-Bromopropyl)pyrazolo[1,5-a]pyrimidine chemical structure, C9H10BrN3, CAS 2228729-51-7
6-(2-Bromopropyl)pyrazolo[1,5-a]pyrimidine
CAS 2228729-51-7C9H10BrN3
2,2-Dimethyl-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol chemical structure, C11H15N3O, CAS 2229555-34-2
2,2-Dimethyl-3-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-1-ol
CAS 2229555-34-2C11H15N3O
O-(1-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethyl)hydroxylamine chemical structure, C8H10N4O, CAS 2228751-72-0
O-(1-{Pyrazolo[1,5-a]pyrimidin-6-yl}ethyl)hydroxylamine
CAS 2228751-72-0C8H10N4O
3-{Pyrazolo[1,5-a]pyrimidin-6-yl}prop-2-en-1-amine chemical structure, C9H10N4, CAS 2229680-85-5
3-{Pyrazolo[1,5-a]pyrimidin-6-yl}prop-2-en-1-amine
CAS 2229680-85-5C9H10N4
(2S)-4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-ol chemical structure, C10H13N3O, CAS 2227729-70-4
(2S)-4-{Pyrazolo[1,5-a]pyrimidin-6-yl}butan-2-ol
CAS 2227729-70-4C10H13N3O
2-Methyl-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine chemical structure, C10H14N4, CAS 2229263-79-8
2-Methyl-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine
CAS 2229263-79-8C10H14N4
6-Bromopyrazolo[1,5-a]pyrimidine-3-sulfonamide chemical structure, C6H5BrN4O2S, CAS 2167306-33-2
6-Bromopyrazolo[1,5-a]pyrimidine-3-sulfonamide
CAS 2167306-33-2C6H5BrN4O2S
3-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-one chemical structure, C9H10N4O, CAS 2228578-13-8
3-Amino-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-one
CAS 2228578-13-8C9H10N4O
3-Chloro-2-methylpyrazolo[1,5-a]pyrimidine-6-sulfonyl fluoride chemical structure, C7H5ClFN3O2S, CAS 2138396-79-7
3-Chloro-2-methylpyrazolo[1,5-a]pyrimidine-6-sulfonyl fluoride
CAS 2138396-79-7C7H5ClFN3O2S
3-Cyanopyrazolo[1,5-a]pyrimidine-6-sulfonyl fluoride chemical structure, C7H3FN4O2S, CAS 2137744-66-0
3-Cyanopyrazolo[1,5-a]pyrimidine-6-sulfonyl fluoride
CAS 2137744-66-0C7H3FN4O2S
tert-Butyl N-[5-(3-{[(tert-butoxy)carbonyl]amino}propyl)pyrazolo[1,5-a]pyrimidin-6-yl]carbamate chemical structure, C19H29N5O4, CAS 2416228-99-2
tert-Butyl N-[5-(3-{[(tert-butoxy)carbonyl]amino}propyl)pyrazolo[1,5-a]pyrimidin-6-yl]carbamate
CAS 2416228-99-2C19H29N5O4
N-(3-Amino-4-methylpentyl)-3-chloro-N-methylpyrazolo[1,5-a]pyrimidine-2-carboxamide hydrochloride chemical structure, C14H21Cl2N5O, CAS 2418694-99-0
N-(3-Amino-4-methylpentyl)-3-chloro-N-methylpyrazolo[1,5-a]pyrimidine-2-carboxamide hydrochloride
CAS 2418694-99-0C14H21Cl2N5O
tert-Butyl N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-yl)carbamate chemical structure, C14H18N4O3, CAS 2229374-06-3
tert-Butyl N-(1-oxo-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-yl)carbamate
CAS 2229374-06-3C14H18N4O3
2-{Pyrazolo[1,5-a]pyrimidin-6-yl}propanal chemical structure, C9H9N3O, CAS 2228372-38-9
2-{Pyrazolo[1,5-a]pyrimidin-6-yl}propanal
CAS 2228372-38-9C9H9N3O
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}prop-2-enal chemical structure, C9H7N3O, CAS 2229662-76-2
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}prop-2-enal
CAS 2229662-76-2C9H7N3O
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}propanal chemical structure, C9H9N3O, CAS 2228975-65-1
3-{Pyrazolo[1,5-a]pyrimidin-2-yl}propanal
CAS 2228975-65-1C9H9N3O
3-Amino-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2228387-13-9
3-Amino-2-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
CAS 2228387-13-9C9H12N4O
3-Amino-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol chemical structure, C9H12N4O, CAS 2228201-44-1
3-Amino-3-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-1-ol
CAS 2228201-44-1C9H12N4O
2-Azido-2-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol chemical structure, C8H8N6O, CAS 2229010-41-5
2-Azido-2-{pyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-ol
CAS 2229010-41-5C8H8N6O
1-Amino-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-ol chemical structure, C9H12N4O, CAS 2228361-61-1
1-Amino-2-{pyrazolo[1,5-a]pyrimidin-6-yl}propan-2-ol
CAS 2228361-61-1C9H12N4O

Only the first 1,920 are listed here. Use the substructure search to filter further.