Murcko scaffold
Pyrazolo(1,5-a)pyrimidine scaffold
2,195 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 2,195
- With full pages
- 244
Scaffold SMILES
c1cnc2ccnn2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 529 to 576 of 2,195 chemicals
![7-Amino-2-isopropyl-5-methylpyrazolo[1,5-a]pyrimidine-6-carbaldehyde chemical structure, C11H14N4O, CAS 1245900-66-6](/s/NIBONKGGLBCCOK-UHFFFAOYSA-N.svg)
7-Amino-2-isopropyl-5-methylpyrazolo[1,5-a]pyrimidine-6-carbaldehyde
CAS 1245900-66-6C11H14N4O
![(7-Amino-2-isopropyl-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)methanol chemical structure, C11H16N4O, CAS 1245900-65-5](/s/LRBYWBMMKWHETO-UHFFFAOYSA-N.svg)
(7-Amino-2-isopropyl-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)methanol
CAS 1245900-65-5C11H16N4O
![6-Methoxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H7N3O3, CAS 1356016-93-7](/s/VGYKDJPYLUPHEA-UHFFFAOYSA-N.svg)
6-Methoxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1356016-93-7C8H7N3O3
![6-(3-Hydroxy-propyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester chemical structure, C12H15N3O3, CAS 1356016-70-0](/s/HQDUAAHCWIORFN-UHFFFAOYSA-N.svg)
6-(3-Hydroxy-propyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester
CAS 1356016-70-0C12H15N3O3
![5-Chloropyrazolo[1,5-a]pyrimidine-3-carbonyl chloride chemical structure, C7H3Cl2N3O, CAS 1224944-47-1](/s/ZMMSLIZEFOZPOU-UHFFFAOYSA-N.svg)
5-Chloropyrazolo[1,5-a]pyrimidine-3-carbonyl chloride
CAS 1224944-47-1C7H3Cl2N3O
![Sodium pyrazolo[1,5-a]pyrimidin-5-olate chemical structure, C6H4N3NaO, CAS 1224944-43-7](/s/GXISRYWBYOPHFY-UHFFFAOYSA-M.svg)
Sodium pyrazolo[1,5-a]pyrimidin-5-olate
CAS 1224944-43-7C6H4N3NaO
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C8H6ClN3O2, CAS 1224944-51-7](/s/FDJUGKZMZUVEJD-UHFFFAOYSA-N.svg)
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1224944-51-7C8H6ClN3O2
Ethyl 5-chloropyrazolo(1,5-a)pyrimidine-3-carboxylate
CAS 1224944-77-7C9H8ClN3O2
![5-Chloro-N-isopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide chemical structure, C10H11ClN4O, CAS 1224944-50-6](/s/APHJHKYTKHOWTA-UHFFFAOYSA-N.svg)
5-Chloro-N-isopropylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CAS 1224944-50-6C10H11ClN4O
Pyrazolo(1,5-a)pyrimidin-6-ol
CAS 1580489-59-3C6H5N3O
5-Chloropyrazolo(1,5-a)pyrimidine-3-carbaldehyde
CAS 1256162-94-3C7H4ClN3O
![6-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidine chemical structure, C10H12BrN3, CAS 916256-69-4](/s/UNGBTHNRBPHIRC-UHFFFAOYSA-N.svg)
6-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidine
CAS 916256-69-4C10H12BrN3
![2-tert-Butyl-6-trimethylsilanylethynyl-pyrazolo[1,5-a]pyrimidine chemical structure, C15H21N3Si, CAS 1312413-72-1](/s/KCRLCYJAYHMYLQ-UHFFFAOYSA-N.svg)
2-tert-Butyl-6-trimethylsilanylethynyl-pyrazolo[1,5-a]pyrimidine
CAS 1312413-72-1C15H21N3Si
![6-Bromo-2-isopropylpyrazolo[1,5-a]pyrimidine chemical structure, C9H10BrN3, CAS 1296224-38-8](/s/GNPYENKJJALUMM-UHFFFAOYSA-N.svg)
6-Bromo-2-isopropylpyrazolo[1,5-a]pyrimidine
CAS 1296224-38-8C9H10BrN3
![7-Isopropylpyrazolo[1,5-a]pyrimidine chemical structure, C9H11N3, CAS 2162239-04-3](/s/OABDYZWBDHQMDL-UHFFFAOYSA-N.svg)
7-Isopropylpyrazolo[1,5-a]pyrimidine
CAS 2162239-04-3C9H11N3
![3-Methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C8H7N3O2, CAS 1784434-49-6](/s/OAVOUQXECYGUKV-UHFFFAOYSA-N.svg)
3-Methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 1784434-49-6C8H7N3O2
![1-(Pyrazolo[1,5-a]pyrimidin-2-yl)ethan-1-one chemical structure, C8H7N3O, CAS 1558214-37-1](/s/REXXFXMDRNKMQE-UHFFFAOYSA-N.svg)
1-(Pyrazolo[1,5-a]pyrimidin-2-yl)ethan-1-one
CAS 1558214-37-1C8H7N3O
![7-Chloro-2,3-dimethylpyrazolo[1,5-A]pyrimidine chemical structure, C8H8ClN3, CAS 4879-18-9](/s/DYSUPRCLGKYVMC-UHFFFAOYSA-N.svg)
7-Chloro-2,3-dimethylpyrazolo[1,5-A]pyrimidine
CAS 4879-18-9C8H8ClN3
![6-Fluoropyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C7H4FN3O2, CAS 1205124-81-7](/s/JMJYLAGSNGCHNP-UHFFFAOYSA-N.svg)
6-Fluoropyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1205124-81-7C7H4FN3O2
![6-Chloropyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C7H4ClN3O2, CAS 1204926-24-8](/s/HMZCJEAFCHYUSU-UHFFFAOYSA-N.svg)
6-Chloropyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1204926-24-8C7H4ClN3O2
![Ethyl 6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C9H8FN3O2, CAS 1204926-19-1](/s/MIWAQWDSRLXHSR-UHFFFAOYSA-N.svg)
Ethyl 6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1204926-19-1C9H8FN3O2
![3-Bromo-5,7-dichloro-6-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H4BrCl2N3, CAS 934297-58-2](/s/HFALLSGFGXDBOV-UHFFFAOYSA-N.svg)
3-Bromo-5,7-dichloro-6-methylpyrazolo[1,5-a]pyrimidine
CAS 934297-58-2C7H4BrCl2N3
![7-(Methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C9H7N3O4, CAS 916212-01-6](/s/JZTGDLSXUIBCCI-UHFFFAOYSA-N.svg)
7-(Methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 916212-01-6C9H7N3O4
![3-Fluoro-7-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C9H6FN3O4, CAS 916212-02-7](/s/OONKTHVZEHAEMI-UHFFFAOYSA-N.svg)
3-Fluoro-7-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 916212-02-7C9H6FN3O4
- 3-Bromo-7-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid916212-06-1C9H6BrN3O4
- Methyl 3-fluoro-5-methylpyrazolo[1,5-a]pyrimidine-7-carboxylate916211-88-6C9H8FN3O2
- Methyl 6-fluoro-5-methylpyrazolo[1,5-a]pyrimidine-7-carboxylate916211-95-5C9H8FN3O2
- 2-Chloro-5-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid916212-09-4C9H6ClN3O4
- 3-Fluoro-5-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid916212-03-8C9H6FN3O4
- 3-Chloro-5-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid916212-07-2C9H6ClN3O4
- 5-(Methoxycarbonyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid916212-10-7C10H6F3N3O4
- Methyl 3-fluoro-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylate916211-89-7C9H8FN3O2
- 6-Fluoro-7-(methoxycarbonyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid916212-11-8C9H6FN3O4
- 2-(Methoxycarbonyl)-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid943760-25-6C10H9N3O4
- 7-Bromo-6-fluoro-5-methylpyrazolo[1,5-a]pyrimidine916211-94-4C7H5BrFN3
- 2,7-Dimethylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid methyl ester916211-78-4C10H11N3O2
- 5-(Methoxycarbonyl)-2-methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid916212-08-3C10H9N3O4
- 3-Chloro-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid methyl ester916213-94-0C9H8ClN3O2
- 7-(tert-Butyl) 5-methyl 3-fluoropyrazolo[1,5-a]pyrimidine-5,7-dicarboxylate943845-95-2C13H14FN3O4
- N-(Propan-2-yl)pyrazolo[1,5-a]pyrimidin-5-amine1544989-38-9C9H12N4
- 6-Bromo-3-methylpyrazolo[1,5-a]pyrimidine1211578-31-2C7H6BrN3
- 2-(Propan-2-yl)pyrazolo(1,5-a)pyrimidine2138410-95-2C9H11N3
- 7-Methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid1030019-36-3C8H7N3O2
- Methyl 7-chloropyrazolo[1,5-a]pyrimidine-5-carboxylate29274-19-9C8H6ClN3O2
- 7-Chloropyrazolo[1,5-a]pyrimidine-5-carboxylic acid1030019-33-0C7H4ClN3O2
- 3-Bromo-7-chloro-2,5-dimethylpyrazolo[1,5-a]pyrimidine885220-89-3C8H7BrClN3
- [3-(Ethoxycarbonyl)pyrazolo[1,5-a]pyrimidin-6-yl]boronic acid1065083-02-4C9H10BN3O4
- 6-Boronopyrazolo[1,5-a]pyrimidine-3-carboxylic acid1065083-05-7C7H6BN3O4
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