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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 385 to 432 of 2,195 chemicals

3-(3-Carbamoyl-5,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)propanoic acid chemical structure, C12H14N4O3, CAS 1072069-75-0
3-(3-Carbamoyl-5,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)propanoic acid
CAS 1072069-75-0C12H14N4O3
3,7-Diethyl 6-(3-hydroxypropyl)pyrazolo[1,5-a]pyrimidine-3,7-dicarboxylate chemical structure, C15H19N3O5, CAS 1146289-94-2
3,7-Diethyl 6-(3-hydroxypropyl)pyrazolo[1,5-a]pyrimidine-3,7-dicarboxylate
CAS 1146289-94-2C15H19N3O5
Ethyl 6-(3-chloropropyl)-2-methylpyrazolo[1,5-a]pyrimidine-7-carboxylate chemical structure, C13H16ClN3O2, CAS 1087789-07-8
Ethyl 6-(3-chloropropyl)-2-methylpyrazolo[1,5-a]pyrimidine-7-carboxylate
CAS 1087789-07-8C13H16ClN3O2
Ethyl 6-(3-bromopropyl)-2-methylpyrazolo[1,5-a]pyrimidine-7-carboxylate chemical structure, C13H16BrN3O2, CAS 1087798-41-1
Ethyl 6-(3-bromopropyl)-2-methylpyrazolo[1,5-a]pyrimidine-7-carboxylate
CAS 1087798-41-1C13H16BrN3O2
2-(3-Aminopropyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile hydrochloride chemical structure, C12H16ClN5, CAS 1172725-56-2
2-(3-Aminopropyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile hydrochloride
CAS 1172725-56-2C12H16ClN5
5,7-Dimethylpyrazolo[1,5-A]pyrimidine-3-carbohydrazide chemical structure, C9H11N5O, CAS 1094521-64-8
5,7-Dimethylpyrazolo[1,5-A]pyrimidine-3-carbohydrazide
CAS 1094521-64-8C9H11N5O
2-({5,7-Dimethylpyrazolo[1,5-a]pyrimidin-3-yl}formamido)acetic acid chemical structure, C11H12N4O3, CAS 1094463-86-1
2-({5,7-Dimethylpyrazolo[1,5-a]pyrimidin-3-yl}formamido)acetic acid
CAS 1094463-86-1C11H12N4O3
(1-{2,7-Dimethylpyrazolo[1,5-a]pyrimidin-6-yl}ethyl)(ethyl)amine chemical structure, C12H18N4, CAS 1038250-92-8
(1-{2,7-Dimethylpyrazolo[1,5-a]pyrimidin-6-yl}ethyl)(ethyl)amine
CAS 1038250-92-8C12H18N4
2-(1-{2,7-Dimethylpyrazolo[1,5-a]pyrimidin-6-yl}-N-methylformamido)acetic acid chemical structure, C12H14N4O3, CAS 1098389-14-0
2-(1-{2,7-Dimethylpyrazolo[1,5-a]pyrimidin-6-yl}-N-methylformamido)acetic acid
CAS 1098389-14-0C12H14N4O3
Methyl 2-({5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl}formamido)-3-hydroxypropanoate chemical structure, C13H16N4O4, CAS 1485818-04-9
Methyl 2-({5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl}formamido)-3-hydroxypropanoate
CAS 1485818-04-9C13H16N4O4
Methyl 2,5,7-trimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C11H13N3O2, CAS 1158418-66-6
Methyl 2,5,7-trimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1158418-66-6C11H13N3O2
2,5,7-Trimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C10H11N3O2, CAS 1158269-53-4
2,5,7-Trimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1158269-53-4C10H11N3O2
7-Chloropyrazolo[1,5-a]pyrimidin-5-amine chemical structure, C6H5ClN4, CAS 1189852-04-7
7-Chloropyrazolo[1,5-a]pyrimidin-5-amine
CAS 1189852-04-7C6H5ClN4
7-Chloro-2-methylpyrazolo(1,5-a)pyrimidin-5-amine chemical structure, C7H7ClN4, CAS 1189852-05-8
7-Chloro-2-methylpyrazolo(1,5-a)pyrimidin-5-amine
CAS 1189852-05-8C7H7ClN4
7-Chloro-2-ethylpyrazolo[1,5-a]pyrimidin-5-amine chemical structure, C8H9ClN4, CAS 1189852-06-9
7-Chloro-2-ethylpyrazolo[1,5-a]pyrimidin-5-amine
CAS 1189852-06-9C8H9ClN4
3-Bromo-5-methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C8H6BrN3O2, CAS 1011355-16-0
3-Bromo-5-methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 1011355-16-0C8H6BrN3O2
Ethyl 6-bromopyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C9H8BrN3O2, CAS 1027511-41-6
Ethyl 6-bromopyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1027511-41-6C9H8BrN3O2
Ethyl 6-chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C11H12ClN3O2, CAS 1035835-21-2
Ethyl 6-chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1035835-21-2C11H12ClN3O2
2-Methylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride chemical structure, C8H6ClN3O, CAS 96319-39-0
2-Methylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride
CAS 96319-39-0C8H6ClN3O
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride chemical structure, C9H8ClN3O, CAS 114040-07-2
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride
CAS 114040-07-2C9H8ClN3O
7-Amino-3-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C8H8N4O2, CAS 89977-62-8
7-Amino-3-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 89977-62-8C8H8N4O2
5-Butyl-7-ethoxypyrazolo[1,5-a]pyrimidine chemical structure, C12H17N3O, CAS 189018-32-4
5-Butyl-7-ethoxypyrazolo[1,5-a]pyrimidine
CAS 189018-32-4C12H17N3O
7-Amino-5-isopropylpyrazolo[1,5-a]pyrimidine-6-carbonitrile chemical structure, C10H11N5, CAS 893424-58-3
7-Amino-5-isopropylpyrazolo[1,5-a]pyrimidine-6-carbonitrile
CAS 893424-58-3C10H11N5
5-Methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C8H6N4, CAS 879900-25-1
5-Methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 879900-25-1C8H6N4