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Murcko scaffold

4-Phenylpyrimidin-2-ol scaffold

102 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 13
Chemicals: 102
With full pages: 3

Scaffold SMILES

O=c1nc(-c2ccccc2)cc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 4-Phenylpyrimidin-2-ol page

Murcko scaffold O=c1nc(-c2ccccc2)cc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 102 chemicals

6-(2,4-Dichlorophenyl)-2-hydroxy-4-(trifluoromethyl)pyrimidine chemical structure, C11H5Cl2F3N2O, CAS 951231-95-1

6-(2,4-Dichlorophenyl)-2-hydroxy-4-(trifluoromethyl)pyrimidine

CAS 951231-95-1C₁₁H₅Cl₂F₃N₂O

4-(4-Chlorophenyl)pyrimidin-2-ol chemical structure, C10H7ClN2O, CAS 361430-03-7

4-(4-Chlorophenyl)pyrimidin-2-ol

CAS 361430-03-7C₁₀H₇ClN₂O

4-(4-Fluorophenyl)-2-hydroxy-6-isopropylpyrimidine-5-carbonitrile chemical structure, C14H12FN3O, CAS 1092843-99-6

4-(4-Fluorophenyl)-2-hydroxy-6-isopropylpyrimidine-5-carbonitrile

CAS 1092843-99-6C₁₄H₁₂FN₃O

1,6-Dimethyl-4-phenylpyrimidin-2(1H)-one chemical structure, C12H12N2O, CAS 38747-63-6

1,6-Dimethyl-4-phenylpyrimidin-2(1H)-one

CAS 38747-63-6C₁₂H₁₂N₂O

Methyl 2-hydroxy-6-phenylpyrimidine-4-carboxylate chemical structure, C12H10N2O3, CAS 1181234-85-4

Methyl 2-hydroxy-6-phenylpyrimidine-4-carboxylate

CAS 1181234-85-4C₁₂H₁₀N₂O₃

4-(3-Aminophenyl)-1,2-dihydropyrimidin-2-one chemical structure, C10H9N3O, CAS 1225516-09-5

4-(3-Aminophenyl)-1,2-dihydropyrimidin-2-one

CAS 1225516-09-5C₁₀H₉N₃O

Ethyl 2-[4-(3-fluorophenyl)-2-oxo-1(2H)-pyrimidinyl]acetate chemical structure, C14H13FN2O3, CAS 1400636-36-3

Ethyl 2-[4-(3-fluorophenyl)-2-oxo-1(2H)-pyrimidinyl]acetate

CAS 1400636-36-3C₁₄H₁₃FN₂O₃

4-(4-Bromophenyl)pyrimidin-2-ol chemical structure, C10H7BrN2O, CAS 1695830-36-4

4-(4-Bromophenyl)pyrimidin-2-ol

CAS 1695830-36-4C₁₀H₇BrN₂O

4-(4-Iodo-3,5-dimethylphenyl)-1-methylpyrimidin-2(1H)-one chemical structure, C13H13IN2O, CAS 1458655-69-0

4-(4-Iodo-3,5-dimethylphenyl)-1-methylpyrimidin-2(1H)-one

CAS 1458655-69-0C₁₃H₁₃IN₂O

6-(3-Bromophenyl)-2-hydroxy-4-(trifluoromethyl)pyrimidine chemical structure, C11H6BrF3N2O, CAS 1271477-68-9

6-(3-Bromophenyl)-2-hydroxy-4-(trifluoromethyl)pyrimidine

CAS 1271477-68-9C₁₁H₆BrF₃N₂O

6-(2,5-Dichlorophenyl)-2-hydroxy-4-(trifluoromethyl)pyrimidine chemical structure, C11H5Cl2F3N2O, CAS 1820712-54-6

6-(2,5-Dichlorophenyl)-2-hydroxy-4-(trifluoromethyl)pyrimidine

CAS 1820712-54-6C₁₁H₅Cl₂F₃N₂O

2-Hydroxy-6-(m-tolyl)-4-(trifluoromethyl)pyrimidine chemical structure, C12H9F3N2O, CAS 1271473-57-4

2-Hydroxy-6-(m-tolyl)-4-(trifluoromethyl)pyrimidine

CAS 1271473-57-4C₁₂H₉F₃N₂O

2-Hydroxy-6-(o-tolyl)-4-(trifluoromethyl)pyrimidine chemical structure, C12H9F3N2O, CAS 1271476-50-6

2-Hydroxy-6-(o-tolyl)-4-(trifluoromethyl)pyrimidine

CAS 1271476-50-6C₁₂H₉F₃N₂O

2-Hydroxy-6-(4-nitrophenyl)-4-(trifluoromethyl)pyrimidine chemical structure, C11H6F3N3O3, CAS 1271477-54-3

2-Hydroxy-6-(4-nitrophenyl)-4-(trifluoromethyl)pyrimidine

CAS 1271477-54-3C₁₁H₆F₃N₃O₃

2-Hydroxy-6-(3-nitrophenyl)-4-(trifluoromethyl)pyrimidine chemical structure, C11H6F3N3O3, CAS 1271475-82-1

2-Hydroxy-6-(3-nitrophenyl)-4-(trifluoromethyl)pyrimidine

CAS 1271475-82-1C₁₁H₆F₃N₃O₃

4-(3-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2(1H)-one chemical structure, C12H9F3N2O2, CAS 1225573-88-5

4-(3-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2(1H)-one

CAS 1225573-88-5C₁₂H₉F₃N₂O₂

Methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2-dihydropyrimidine-5-carboxylate chemical structure, C13H11ClN2O3, CAS 868755-06-0

Methyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2-dihydropyrimidine-5-carboxylate

CAS 868755-06-0C₁₃H₁₁ClN₂O₃

2-Hydroxy-4-(2-chlorophenyl)-6-methylpyrimidine chemical structure, C11H9ClN2O, CAS 1412954-76-7

2-Hydroxy-4-(2-chlorophenyl)-6-methylpyrimidine

CAS 1412954-76-7C₁₁H₉ClN₂O

2-Hydroxy-4-(3-chlorophenyl)-6-methylpyrimidine chemical structure, C11H9ClN2O, CAS 1412959-38-6

2-Hydroxy-4-(3-chlorophenyl)-6-methylpyrimidine

CAS 1412959-38-6C₁₁H₉ClN₂O

2-Hydroxy-4-(2-fluorophenyl)-6-methylpyrimidine chemical structure, C11H9FN2O, CAS 1412958-79-2

2-Hydroxy-4-(2-fluorophenyl)-6-methylpyrimidine

CAS 1412958-79-2C₁₁H₉FN₂O

5-Fluoro-6-phenylpyrimidin-2(1H)-one chemical structure, C10H7FN2O, CAS 1695241-86-1

5-Fluoro-6-phenylpyrimidin-2(1H)-one

CAS 1695241-86-1C₁₀H₇FN₂O

6-(4-Methoxy-2-methylphenyl)-1,5-dimethyl-2(1H)-pyrimidinone chemical structure, C14H16N2O2, CAS 1643462-89-8

6-(4-Methoxy-2-methylphenyl)-1,5-dimethyl-2(1H)-pyrimidinone

CAS 1643462-89-8C₁₄H₁₆N₂O₂

4-(Difluoromethyl)-6-(4-fluorophenyl)pyrimidin-2-ol chemical structure, C11H7F3N2O, CAS 1271477-66-7

4-(Difluoromethyl)-6-(4-fluorophenyl)pyrimidin-2-ol

CAS 1271477-66-7C₁₁H₇F₃N₂O

4-(Difluoromethyl)-6-phenylpyrimidin-2(1H)-one chemical structure, C11H8F2N2O, CAS 1271476-71-1

4-(Difluoromethyl)-6-phenylpyrimidin-2(1H)-one

CAS 1271476-71-1C₁₁H₈F₂N₂O