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Murcko scaffold

Ring system with 3 rings and 14 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
5
With full pages
3
Scaffold SMILES

c1nnc(-c2cc3c(s2)CCCC3)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nnc(-c2cc3c(s2)CCCC3)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

2-(Chloromethyl)-5-(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazole chemical structure, C11H11ClN2OS, CAS 796106-53-1
2-(Chloromethyl)-5-(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazole
CAS 796106-53-1C11H11ClN2OS
2-(5-tert-Butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-(chloromethyl)-1,3,4-oxadiazole chemical structure, C15H19ClN2OS, CAS 851721-80-7
2-(5-tert-Butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-(chloromethyl)-1,3,4-oxadiazole
CAS 851721-80-7C15H19ClN2OS
N-(1-Cyano-1,2-dimethylpropyl)-2-{[5-(5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}propanamide chemical structure, C20H26N4O2S2, CAS 1014083-20-5
N-(1-Cyano-1,2-dimethylpropyl)-2-{[5-(5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}propanamide
CAS 1014083-20-5C20H26N4O2S2
N-(1-Cyano-1,2-dimethylpropyl)-2-{[5-(5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide chemical structure, C19H24N4O2S2, CAS 1007739-65-2
N-(1-Cyano-1,2-dimethylpropyl)-2-{[5-(5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide
CAS 1007739-65-2C19H24N4O2S2
5-(4,5,6,7-Tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazol-2-amine chemical structure, C10H11N3OS, CAS 1019450-61-3
5-(4,5,6,7-Tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazol-2-amine
CAS 1019450-61-3C10H11N3OS