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Murcko scaffold

Ring system with 3 rings and 19 atoms

88 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
88
With full pages
5
Scaffold SMILES

O=C(Nc1nnc(-c2cccs2)o1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nnc(-c2cccs2)o1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 88 chemicals

4-(N,N-Dimethylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C15H14N4O4S2, CAS 533871-87-3
4-(N,N-Dimethylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 533871-87-3C15H14N4O4S2
4-(N,N-Diethylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C17H18N4O4S2, CAS 533871-88-4
4-(N,N-Diethylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 533871-88-4C17H18N4O4S2
4-(Dipropylsulfamoyl)-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C19H22N4O4S2, CAS 533871-89-5
4-(Dipropylsulfamoyl)-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide
CAS 533871-89-5C19H22N4O4S2
4-[Butyl(ethyl)sulfamoyl]-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C19H22N4O4S2, CAS 533871-92-0
4-[Butyl(ethyl)sulfamoyl]-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide
CAS 533871-92-0C19H22N4O4S2
4-(N,N-Diallylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C19H18N4O4S2, CAS 533871-95-3
4-(N,N-Diallylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 533871-95-3C19H18N4O4S2
4-(N,N-Diisobutylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C21H26N4O4S2, CAS 533872-11-6
4-(N,N-Diisobutylsulfamoyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 533872-11-6C21H26N4O4S2
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-4-(diethylsulfamoyl)benzamide chemical structure, C17H17ClN4O4S2, CAS 533872-18-3
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-4-(diethylsulfamoyl)benzamide
CAS 533872-18-3C17H17ClN4O4S2
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-4-(dipropylsulfamoyl)benzamide chemical structure, C19H21ClN4O4S2, CAS 533872-19-4
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-4-(dipropylsulfamoyl)benzamide
CAS 533872-19-4C19H21ClN4O4S2
4-[Butyl(methyl)sulfamoyl]-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C18H19ClN4O4S2, CAS 533872-21-8
4-[Butyl(methyl)sulfamoyl]-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 533872-21-8C18H19ClN4O4S2
4-[Butyl(ethyl)sulfamoyl]-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C19H21ClN4O4S2, CAS 533872-22-9
4-[Butyl(ethyl)sulfamoyl]-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 533872-22-9C19H21ClN4O4S2
4-[Bis(2-methylpropyl)sulfamoyl]-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C21H25ClN4O4S2, CAS 533872-41-2
4-[Bis(2-methylpropyl)sulfamoyl]-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 533872-41-2C21H25ClN4O4S2
N-(5-Thiophen-2-yl-1,3,4-oxadiazol-2-yl)-3-(trifluoromethyl)benzamide chemical structure, C14H8F3N3O2S, CAS 865287-80-5
N-(5-Thiophen-2-yl-1,3,4-oxadiazol-2-yl)-3-(trifluoromethyl)benzamide
CAS 865287-80-5C14H8F3N3O2S
3,4-Dimethyl-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C15H13N3O2S, CAS 865287-82-7
3,4-Dimethyl-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 865287-82-7C15H13N3O2S
Methyl 4-((5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)carbamoyl)benzoate chemical structure, C15H11N3O4S, CAS 865287-91-8
Methyl 4-((5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)carbamoyl)benzoate
CAS 865287-91-8C15H11N3O4S
4-tert-Butyl-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C17H17N3O2S, CAS 865287-99-6
4-tert-Butyl-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)benzamide
CAS 865287-99-6C17H17N3O2S
4-(Dimethylamino)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C15H14N4O2S, CAS 865288-04-6
4-(Dimethylamino)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 865288-04-6C15H14N4O2S
4-Isopropoxy-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C16H15N3O3S, CAS 865288-06-8
4-Isopropoxy-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 865288-06-8C16H15N3O3S
N-(5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C13H8ClN3O2S, CAS 865288-13-7
N-(5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 865288-13-7C13H8ClN3O2S
4-Chloro-N-(5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C13H7Cl2N3O2S, CAS 865288-14-8
4-Chloro-N-(5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 865288-14-8C13H7Cl2N3O2S
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-3-nitrobenzamide chemical structure, C13H7ClN4O4S, CAS 865288-16-0
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-3-nitrobenzamide
CAS 865288-16-0C13H7ClN4O4S
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-4-methoxybenzamide chemical structure, C14H10ClN3O3S, CAS 865288-18-2
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-4-methoxybenzamide
CAS 865288-18-2C14H10ClN3O3S
N-(5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-4-cyanobenzamide chemical structure, C14H7ClN4O2S, CAS 865288-20-6
N-(5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-4-cyanobenzamide
CAS 865288-20-6C14H7ClN4O2S
Methyl 4-((5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)carbamoyl)benzoate chemical structure, C15H10ClN3O4S, CAS 865543-60-8
Methyl 4-((5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl)carbamoyl)benzoate
CAS 865543-60-8C15H10ClN3O4S
3-Butoxy-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C17H16ClN3O3S, CAS 865543-61-9
3-Butoxy-N-[5-(5-chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 865543-61-9C17H16ClN3O3S