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Murcko scaffold

Ring system with 3 rings and 18 atoms

61 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
61
With full pages
28
Scaffold SMILES

c1ccc(CSc2nnc(-c3ccco3)[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2nnc(-c3ccco3)[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

3-[(4-Chlorophenyl)methylsulfanyl]-5-(furan-2-yl)-4-methyl-1,2,4-triazole chemical structure, C14H12ClN3OS, CAS 384859-17-0
3-[(4-Chlorophenyl)methylsulfanyl]-5-(furan-2-yl)-4-methyl-1,2,4-triazole
CAS 384859-17-0C14H12ClN3OS
3-(Furan-2-yl)-4-methyl-5-[[3-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole chemical structure, C15H12F3N3OS, CAS 676458-76-7
3-(Furan-2-yl)-4-methyl-5-[[3-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole
CAS 676458-76-7C15H12F3N3OS
4-Ethyl-3-(2-furyl)-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole chemical structure, C16H14F3N3OS, CAS 618413-63-1
4-Ethyl-3-(2-furyl)-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole
CAS 618413-63-1C16H14F3N3OS
3-(2-Furyl)-5-((3-methoxybenzyl)thio)-4-methyl-4H-1,2,4-triazole chemical structure, C15H15N3O2S, CAS 678554-12-6
3-(2-Furyl)-5-((3-methoxybenzyl)thio)-4-methyl-4H-1,2,4-triazole
CAS 678554-12-6C15H15N3O2S
3-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-5-(furan-2-yl)-4-prop-2-enyl-1,2,4-triazole chemical structure, C16H13ClFN3OS, CAS 573937-97-0
3-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-5-(furan-2-yl)-4-prop-2-enyl-1,2,4-triazole
CAS 573937-97-0C16H13ClFN3OS
4-Ethyl-3-(2-furyl)-5-((3-methoxybenzyl)thio)-4H-1,2,4-triazole chemical structure, C16H17N3O2S, CAS 573949-95-8
4-Ethyl-3-(2-furyl)-5-((3-methoxybenzyl)thio)-4H-1,2,4-triazole
CAS 573949-95-8C16H17N3O2S
3-(2-Furyl)-5-[(4-methylphenyl)methylthio]-1,2,4-triazole-4-ylamine chemical structure, C14H14N4OS, CAS 578719-45-6
3-(2-Furyl)-5-[(4-methylphenyl)methylthio]-1,2,4-triazole-4-ylamine
CAS 578719-45-6C14H14N4OS
3-(2-Furyl)-5-{[3-(trifluoromethyl)phenyl]methylthio}-1,2,4-triazole-4-ylamine chemical structure, C14H11F3N4OS, CAS 577963-08-7
3-(2-Furyl)-5-{[3-(trifluoromethyl)phenyl]methylthio}-1,2,4-triazole-4-ylamine
CAS 577963-08-7C14H11F3N4OS
5-(2-Furyl)-4-methyl-3-[(3-methylphenyl)methylthio]-1,2,4-triazole chemical structure, C15H15N3OS, CAS 585560-31-2
5-(2-Furyl)-4-methyl-3-[(3-methylphenyl)methylthio]-1,2,4-triazole
CAS 585560-31-2C15H15N3OS
3-(Benzylsulfanyl)-5-(furan-2-yl)-4H-1,2,4-triazol-4-amine chemical structure, C13H12N4OS, CAS 332943-04-1
3-(Benzylsulfanyl)-5-(furan-2-yl)-4H-1,2,4-triazol-4-amine
CAS 332943-04-1C13H12N4OS
3-(Benzylsulfanyl)-5-(furan-2-yl)-4-methyl-4H-1,2,4-triazole chemical structure, C14H13N3OS, CAS 569644-78-6
3-(Benzylsulfanyl)-5-(furan-2-yl)-4-methyl-4H-1,2,4-triazole
CAS 569644-78-6C14H13N3OS
4-Fluorobenzyl 5-(2-furyl)-4-methyl-4H-1,2,4-triazol-3-yl sulfide chemical structure, C14H12FN3OS, CAS 498550-90-6
4-Fluorobenzyl 5-(2-furyl)-4-methyl-4H-1,2,4-triazol-3-yl sulfide
CAS 498550-90-6C14H12FN3OS
2-Fluorobenzyl 5-(2-furyl)-4-methyl-4H-1,2,4-triazol-3-yl sulfide chemical structure, C14H12FN3OS, CAS 498551-14-7
2-Fluorobenzyl 5-(2-furyl)-4-methyl-4H-1,2,4-triazol-3-yl sulfide
CAS 498551-14-7C14H12FN3OS
3-[(3-Chlorophenyl)methylthio]-5-(2-furyl)-4-prop-2-enyl-1,2,4-triazole chemical structure, C16H14ClN3OS, CAS 677720-82-0
3-[(3-Chlorophenyl)methylthio]-5-(2-furyl)-4-prop-2-enyl-1,2,4-triazole
CAS 677720-82-0C16H14ClN3OS
3-[(3-Fluorophenyl)methylthio]-5-(2-furyl)-4-prop-2-enyl-1,2,4-triazole chemical structure, C16H14FN3OS, CAS 676539-45-0
3-[(3-Fluorophenyl)methylthio]-5-(2-furyl)-4-prop-2-enyl-1,2,4-triazole
CAS 676539-45-0C16H14FN3OS
3-[(2,4-Dichlorophenyl)methylthio]-5-(2-furyl)-4-methyl-1,2,4-triazole chemical structure, C14H11Cl2N3OS, CAS 676339-08-5
3-[(2,4-Dichlorophenyl)methylthio]-5-(2-furyl)-4-methyl-1,2,4-triazole
CAS 676339-08-5C14H11Cl2N3OS
3-(Benzylthio)-4-ethyl-5-(2-furyl)-4H-1,2,4-triazole chemical structure, C15H15N3OS, CAS 618412-84-3
3-(Benzylthio)-4-ethyl-5-(2-furyl)-4H-1,2,4-triazole
CAS 618412-84-3C15H15N3OS
3-[(2,6-Dichlorobenzyl)sulfanyl]-5-(furan-2-yl)-4-methyl-4H-1,2,4-triazole chemical structure, C14H11Cl2N3OS, CAS 676469-92-4
3-[(2,6-Dichlorobenzyl)sulfanyl]-5-(furan-2-yl)-4-methyl-4H-1,2,4-triazole
CAS 676469-92-4C14H11Cl2N3OS
3-((3-Chlorobenzyl)thio)-4-ethyl-5-(2-furyl)-4H-1,2,4-triazole chemical structure, C15H14ClN3OS, CAS 618413-51-7
3-((3-Chlorobenzyl)thio)-4-ethyl-5-(2-furyl)-4H-1,2,4-triazole
CAS 618413-51-7C15H14ClN3OS
3-(2-Furyl)-5-((4-methoxybenzyl)thio)-4-methyl-4H-1,2,4-triazole chemical structure, C15H15N3O2S, CAS 677295-15-7
3-(2-Furyl)-5-((4-methoxybenzyl)thio)-4-methyl-4H-1,2,4-triazole
CAS 677295-15-7C15H15N3O2S
5-[(2,5-Dimethylphenyl)methylthio]-3-(2-furyl)-1,2,4-triazole-4-ylamine chemical structure, C15H16N4OS, CAS 676244-30-7
5-[(2,5-Dimethylphenyl)methylthio]-3-(2-furyl)-1,2,4-triazole-4-ylamine
CAS 676244-30-7C15H16N4OS
3-[(3-Chlorophenyl)methylthio]-5-(2-furyl)-4-methyl-1,2,4-triazole chemical structure, C14H12ClN3OS, CAS 677312-04-8
3-[(3-Chlorophenyl)methylthio]-5-(2-furyl)-4-methyl-1,2,4-triazole
CAS 677312-04-8C14H12ClN3OS
3-[(6-Chloro-2-fluorophenyl)methylthio]-5-(2-furyl)-4-methyl-1,2,4-triazole chemical structure, C14H11ClFN3OS, CAS 676522-21-7
3-[(6-Chloro-2-fluorophenyl)methylthio]-5-(2-furyl)-4-methyl-1,2,4-triazole
CAS 676522-21-7C14H11ClFN3OS
4-Allyl-3-(2-furyl)-5-((4-methylbenzyl)thio)-4H-1,2,4-triazole chemical structure, C17H17N3OS, CAS 573709-38-3
4-Allyl-3-(2-furyl)-5-((4-methylbenzyl)thio)-4H-1,2,4-triazole
CAS 573709-38-3C17H17N3OS