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Murcko scaffold

N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]benzamide scaffold

113 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
113
With full pages
9
Scaffold SMILES

O=C(Nc1nc(-c2cccs2)cs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]benzamide page
Murcko scaffold O=C(Nc1nc(-c2cccs2)cs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 113 chemicals

N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-benzamide chemical structure, C16H13N3O2S2, CAS 395064-97-8
N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-benzamide
CAS 395064-97-8C16H13N3O2S2
4-Nitro-N-(4-thiophen-2-yl-thiazol-2-yl)-benzamide chemical structure, C14H9N3O3S2, CAS 313365-83-2
4-Nitro-N-(4-thiophen-2-yl-thiazol-2-yl)-benzamide
CAS 313365-83-2C14H9N3O3S2
4-Methoxy-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide chemical structure, C15H12N2O2S2, CAS 313224-98-5
4-Methoxy-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide
CAS 313224-98-5C15H12N2O2S2
N-(4-Thiophen-2-yl-thiazol-2-yl)-phthalamic acid chemical structure, C15H10N2O3S2, CAS 325807-37-2
N-(4-Thiophen-2-yl-thiazol-2-yl)-phthalamic acid
CAS 325807-37-2C15H10N2O3S2
4-Fluoro-N-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]benzamide chemical structure, C14H9FN2OS2, CAS 313365-84-3
4-Fluoro-N-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]benzamide
CAS 313365-84-3C14H9FN2OS2
N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]benzamide chemical structure, C14H10N2OS2, CAS 333431-01-9
N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]benzamide
CAS 333431-01-9C14H10N2OS2
N-[4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-2-fluorobenzamide chemical structure, C14H8ClFN2OS2, CAS 391225-37-9
N-[4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-2-fluorobenzamide
CAS 391225-37-9C14H8ClFN2OS2
N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-4-fluorobenzamide chemical structure, C14H8ClFN2OS2, CAS 325986-65-0
N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-4-fluorobenzamide
CAS 325986-65-0C14H8ClFN2OS2
N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-4-methyl-benzamide chemical structure, C17H15N3O2S2, CAS 387383-67-7
N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-4-methyl-benzamide
CAS 387383-67-7C17H15N3O2S2
N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-4-methoxy-benzamide chemical structure, C17H15N3O3S2, CAS 385832-08-6
N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-4-methoxy-benzamide
CAS 385832-08-6C17H15N3O3S2
N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-4-chloro-benzamide chemical structure, C16H12ClN3O2S2, CAS 387834-21-1
N-(5-Acetylamino-4-thiophen-2-yl-thiazol-2-yl)-4-chloro-benzamide
CAS 387834-21-1C16H12ClN3O2S2
N-[4-(5-Bromothiophen-2-yl)-1,3-thiazol-2-yl]-2,4-dimethoxybenzamide chemical structure, C16H13BrN2O3S2, CAS 307510-73-2
N-[4-(5-Bromothiophen-2-yl)-1,3-thiazol-2-yl]-2,4-dimethoxybenzamide
CAS 307510-73-2C16H13BrN2O3S2
N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-4-nitrobenzamide chemical structure, C14H8ClN3O3S2, CAS 325986-59-2
N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-4-nitrobenzamide
CAS 325986-59-2C14H8ClN3O3S2
2-Chloro-5-nitro-N-(4-thiophen-2-yl-1,3-thiazol-2-yl)benzamide chemical structure, C14H8ClN3O3S2, CAS 313549-81-4
2-Chloro-5-nitro-N-(4-thiophen-2-yl-1,3-thiazol-2-yl)benzamide
CAS 313549-81-4C14H8ClN3O3S2
4-(Dimethylsulfamoyl)-N-(4-thiophen-2-yl-2-thiazolyl)benzamide chemical structure, C16H15N3O3S3, CAS 313646-72-9
4-(Dimethylsulfamoyl)-N-(4-thiophen-2-yl-2-thiazolyl)benzamide
CAS 313646-72-9C16H15N3O3S3
N-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-3-(trifluoromethyl)benzamide chemical structure, C15H8ClF3N2OS2, CAS 478260-67-2
N-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-3-(trifluoromethyl)benzamide
CAS 478260-67-2C15H8ClF3N2OS2
4-(N,N-Diethylsulfamoyl)-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide chemical structure, C18H19N3O3S3, CAS 301236-36-2
4-(N,N-Diethylsulfamoyl)-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide
CAS 301236-36-2C18H19N3O3S3
3,4,5-Trimethoxy-N-(4-thiophen-2-yl-1,3-thiazol-2-yl)benzamide chemical structure, C17H16N2O4S2, CAS 300569-78-2
3,4,5-Trimethoxy-N-(4-thiophen-2-yl-1,3-thiazol-2-yl)benzamide
CAS 300569-78-2C17H16N2O4S2
4-Bromo-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide chemical structure, C14H9BrN2OS2, CAS 301236-53-3
4-Bromo-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide
CAS 301236-53-3C14H9BrN2OS2
N-[4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-3-methoxybenzamide chemical structure, C15H11ClN2O2S2, CAS 391225-39-1
N-[4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-3-methoxybenzamide
CAS 391225-39-1C15H11ClN2O2S2
2,4-Dichloro-N-[4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-yl]benzamide chemical structure, C14H7Cl3N2OS2, CAS 325986-66-1
2,4-Dichloro-N-[4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-yl]benzamide
CAS 325986-66-1C14H7Cl3N2OS2
N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-4-cyanobenzamide chemical structure, C15H8ClN3OS2, CAS 325986-72-9
N-(4-(5-Chlorothiophen-2-yl)thiazol-2-yl)-4-cyanobenzamide
CAS 325986-72-9C15H8ClN3OS2
3,5-Dichloro-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide chemical structure, C14H8Cl2N2OS2, CAS 300569-87-3
3,5-Dichloro-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide
CAS 300569-87-3C14H8Cl2N2OS2
2,4-Dichloro-N-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]benzamide chemical structure, C14H8Cl2N2OS2, CAS 5914-15-8
2,4-Dichloro-N-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]benzamide
CAS 5914-15-8C14H8Cl2N2OS2