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Murcko scaffold

4-(Pyridin-2-yl)pyrimidine scaffold

164 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
164
With full pages
6
Scaffold SMILES

c1ccc(-c2ccncn2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyridin-2-yl)pyrimidine page
Murcko scaffold c1ccc(-c2ccncn2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 164 chemicals

2-Methyl-6-(pyridin-2-yl)pyrimidin-4-amine chemical structure, C10H10N4, CAS 90916-54-4
2-Methyl-6-(pyridin-2-yl)pyrimidin-4-amine
CAS 90916-54-4C10H10N4
N-(2-Methyl-6-pyridin-2-ylpyrimidin-4-yl)acetamide chemical structure, C12H12N4O, CAS 91560-14-4
N-(2-Methyl-6-pyridin-2-ylpyrimidin-4-yl)acetamide
CAS 91560-14-4C12H12N4O
2-Methyl-4-pyridin-2-ylpyrimidine chemical structure, C10H9N3, CAS 25194-63-2
2-Methyl-4-pyridin-2-ylpyrimidine
CAS 25194-63-2C10H9N3
4-Hydrazinyl-2-methyl-6-(pyridin-2-yl)pyrimidine chemical structure, C10H11N5, CAS 26069-87-4
4-Hydrazinyl-2-methyl-6-(pyridin-2-yl)pyrimidine
CAS 26069-87-4C10H11N5
4-Chloro-2-methyl-6-(pyridin-2-yl)pyrimidine chemical structure, C10H8ClN3, CAS 25194-62-1
4-Chloro-2-methyl-6-(pyridin-2-yl)pyrimidine
CAS 25194-62-1C10H8ClN3
4-(Pyridin-2-yl)pyrimidin-2-amine chemical structure, C9H8N4, CAS 66521-65-1
4-(Pyridin-2-yl)pyrimidin-2-amine
CAS 66521-65-1C9H8N4
4-(Pyridin-2-yl)pyrimidine chemical structure, C9H7N3, CAS 52997-82-7
4-(Pyridin-2-yl)pyrimidine
CAS 52997-82-7C9H7N3
2-Chloro-4-(pyridin-2-yl)pyrimidine chemical structure, C9H6ClN3, CAS 630423-85-7
2-Chloro-4-(pyridin-2-yl)pyrimidine
CAS 630423-85-7C9H6ClN3
2-Hydrazino-4-(2-pyridyl)pyrimidine chemical structure, C9H9N5, CAS 374081-39-7
2-Hydrazino-4-(2-pyridyl)pyrimidine
CAS 374081-39-7C9H9N5
2-(Methylthio)-4-(2-pyridinyl)pyrimidine chemical structure, C10H9N3S, CAS 374081-38-6
2-(Methylthio)-4-(2-pyridinyl)pyrimidine
CAS 374081-38-6C10H9N3S
4-Chloro-6-(pyridin-2-yl)pyrimidine chemical structure, C9H6ClN3, CAS 284050-18-6
4-Chloro-6-(pyridin-2-yl)pyrimidine
CAS 284050-18-6C9H6ClN3
2,4-Dichloro-6-(pyridin-2-yl)pyrimidine chemical structure, C9H5Cl2N3, CAS 954232-56-5
2,4-Dichloro-6-(pyridin-2-yl)pyrimidine
CAS 954232-56-5C9H5Cl2N3
[4-(Pyridin-2-yl)pyrimidin-2-yl]cyanamide chemical structure, C10H7N5, CAS 1144486-85-0
[4-(Pyridin-2-yl)pyrimidin-2-yl]cyanamide
CAS 1144486-85-0C10H7N5
4-(3-Methylpyridin-2-yl)pyrimidin-2-amine chemical structure, C10H10N4, CAS 1203147-55-0
4-(3-Methylpyridin-2-yl)pyrimidin-2-amine
CAS 1203147-55-0C10H10N4
2-Chloro-4-(6'-bromo-2'-pyridyl)pyrimidine chemical structure, C9H5BrClN3, CAS 1185308-24-0
2-Chloro-4-(6'-bromo-2'-pyridyl)pyrimidine
CAS 1185308-24-0C9H5BrClN3
2-Bromo-4-(6'-chloro-2'-pyridyl)pyrimidine chemical structure, C9H5BrClN3, CAS 1185306-16-4
2-Bromo-4-(6'-chloro-2'-pyridyl)pyrimidine
CAS 1185306-16-4C9H5BrClN3
4-(6-Bromo-2-pyridinyl)-2-pyrimidinamine chemical structure, C9H7BrN4, CAS 1185317-15-0
4-(6-Bromo-2-pyridinyl)-2-pyrimidinamine
CAS 1185317-15-0C9H7BrN4
4-Chloro-6-(6'-bromo-2'-pyridyl)pyrimidine chemical structure, C9H5BrClN3, CAS 1185308-21-7
4-Chloro-6-(6'-bromo-2'-pyridyl)pyrimidine
CAS 1185308-21-7C9H5BrClN3
4-Bromo-6-(6'-chloro-2'-pyridyl)pyrimidine chemical structure, C9H5BrClN3, CAS 1185311-99-2
4-Bromo-6-(6'-chloro-2'-pyridyl)pyrimidine
CAS 1185311-99-2C9H5BrClN3
4-Chloro-2-methyl-6-(6'-bromo-2'-pyridyl)pyrimidine chemical structure, C10H7BrClN3, CAS 1185317-24-1
4-Chloro-2-methyl-6-(6'-bromo-2'-pyridyl)pyrimidine
CAS 1185317-24-1C10H7BrClN3
2-Chloro-4-methyl-6-(6'-bromo-2'-pyridyl)pyrimidine chemical structure, C10H7BrClN3, CAS 1185308-60-4
2-Chloro-4-methyl-6-(6'-bromo-2'-pyridyl)pyrimidine
CAS 1185308-60-4C10H7BrClN3
2-Amino-4-methyl-6-(6'-bromo-2'-pyridyl)pyrimidine chemical structure, C10H9BrN4, CAS 1185312-75-7
2-Amino-4-methyl-6-(6'-bromo-2'-pyridyl)pyrimidine
CAS 1185312-75-7C10H9BrN4
4-Chloro-2-methylthio-6-(6'-bromo-2'-pyridyl)pyrimidine chemical structure, C10H7BrClN3S, CAS 1185311-02-7
4-Chloro-2-methylthio-6-(6'-bromo-2'-pyridyl)pyrimidine
CAS 1185311-02-7C10H7BrClN3S
4-Amino-2-methylthio-6-(6'-bromo-2'-pyridyl)pyrimidine chemical structure, C10H9BrN4S, CAS 1185308-53-5
4-Amino-2-methylthio-6-(6'-bromo-2'-pyridyl)pyrimidine
CAS 1185308-53-5C10H9BrN4S