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Murcko scaffold

Ring system with 3 rings and 23 atoms

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
30
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)C(=Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C(=Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

N-(4-Fluoro-2-methylphenyl)-2,3-diphenylacrylamide chemical structure, C22H18FNO, CAS 512811-86-8
N-(4-Fluoro-2-methylphenyl)-2,3-diphenylacrylamide
CAS 512811-86-8C22H18FNO
N-(2-Fluoro-5-methylphenyl)-2,3-diphenylacrylamide chemical structure, C22H18FNO, CAS 512811-23-3
N-(2-Fluoro-5-methylphenyl)-2,3-diphenylacrylamide
CAS 512811-23-3C22H18FNO
(E)-N-(2-Fluorophenyl)-2,3-diphenylprop-2-enamide chemical structure, C21H16FNO, CAS 587843-26-3
(E)-N-(2-Fluorophenyl)-2,3-diphenylprop-2-enamide
CAS 587843-26-3C21H16FNO
(E)-N-(4-Fluorophenyl)-2,3-diphenylprop-2-enamide chemical structure, C21H16FNO, CAS 587843-30-9
(E)-N-(4-Fluorophenyl)-2,3-diphenylprop-2-enamide
CAS 587843-30-9C21H16FNO
Methyl 4-((2,3-diphenylacryloyl)amino)benzoate chemical structure, C23H19NO3, CAS 307505-17-5
Methyl 4-((2,3-diphenylacryloyl)amino)benzoate
CAS 307505-17-5C23H19NO3
(E)-N-(2-Chloro-5-nitrophenyl)-2,3-diphenylprop-2-enamide chemical structure, C21H15ClN2O3, CAS 599153-83-0
(E)-N-(2-Chloro-5-nitrophenyl)-2,3-diphenylprop-2-enamide
CAS 599153-83-0C21H15ClN2O3
(E)-N-(4-Chloro-2,5-dimethoxyphenyl)-2,3-diphenylprop-2-enamide chemical structure, C23H20ClNO3, CAS 587843-37-6
(E)-N-(4-Chloro-2,5-dimethoxyphenyl)-2,3-diphenylprop-2-enamide
CAS 587843-37-6C23H20ClNO3
(E)-3-(2-Chlorophenyl)-N-(2,4-dimethoxyphenyl)-2-phenylprop-2-enamide chemical structure, C23H20ClNO3, CAS 432508-60-6
(E)-3-(2-Chlorophenyl)-N-(2,4-dimethoxyphenyl)-2-phenylprop-2-enamide
CAS 432508-60-6C23H20ClNO3
N-(4-Methylphenyl)-3-(3-nitrophenyl)-2-phenylprop-2-enamide chemical structure, C22H18N2O3, CAS 432496-82-7
N-(4-Methylphenyl)-3-(3-nitrophenyl)-2-phenylprop-2-enamide
CAS 432496-82-7C22H18N2O3
(E)-3-(2-Chlorophenyl)-N-(3,4-dimethoxyphenyl)-2-phenylprop-2-enamide chemical structure, C23H20ClNO3, CAS 432020-29-6
(E)-3-(2-Chlorophenyl)-N-(3,4-dimethoxyphenyl)-2-phenylprop-2-enamide
CAS 432020-29-6C23H20ClNO3
(AlphaE)-N-phenyl-alpha-(phenylmethylene)benzeneacetamide chemical structure, C21H17NO, CAS 20432-30-8
(AlphaE)-N-phenyl-alpha-(phenylmethylene)benzeneacetamide
CAS 20432-30-8C21H17NO
(E)-N-(3,4-Dimethylphenyl)-2,3-diphenylacrylamide chemical structure, C23H21NO, CAS 5942-02-9
(E)-N-(3,4-Dimethylphenyl)-2,3-diphenylacrylamide
CAS 5942-02-9C23H21NO
N-(2-Ethylphenyl)-2,3-diphenylacrylamide chemical structure, C23H21NO, CAS 5938-25-0
N-(2-Ethylphenyl)-2,3-diphenylacrylamide
CAS 5938-25-0C23H21NO
(E)-2,3-Diphenyl-N-(2,4,6-trimethylphenyl)prop-2-enamide chemical structure, C24H23NO, CAS 1164505-10-5
(E)-2,3-Diphenyl-N-(2,4,6-trimethylphenyl)prop-2-enamide
CAS 1164505-10-5C24H23NO
2-[[(E)-3-(2-Chlorophenyl)-2-phenylprop-2-enoyl]amino]benzamide chemical structure, C22H17ClN2O2, CAS 532940-71-9
2-[[(E)-3-(2-Chlorophenyl)-2-phenylprop-2-enoyl]amino]benzamide
CAS 532940-71-9C22H17ClN2O2
(E)-3-(2-Chlorophenyl)-N-(3-methylsulfanylphenyl)-2-phenylprop-2-enamide chemical structure, C22H18ClNOS, CAS 472971-71-4
(E)-3-(2-Chlorophenyl)-N-(3-methylsulfanylphenyl)-2-phenylprop-2-enamide
CAS 472971-71-4C22H18ClNOS
(E)-N-(3-Fluorophenyl)-3-(3-nitrophenyl)-2-phenylprop-2-enamide chemical structure, C21H15FN2O3, CAS 532419-91-3
(E)-N-(3-Fluorophenyl)-3-(3-nitrophenyl)-2-phenylprop-2-enamide
CAS 532419-91-3C21H15FN2O3
(E)-N-(3-Chloro-4-fluorophenyl)-3-(4-methoxyphenyl)-2-phenylprop-2-enamide chemical structure, C22H17ClFNO2, CAS 472977-12-1
(E)-N-(3-Chloro-4-fluorophenyl)-3-(4-methoxyphenyl)-2-phenylprop-2-enamide
CAS 472977-12-1C22H17ClFNO2
(E)-3-(2-Chlorophenyl)-N-(4-ethoxyphenyl)-2-phenylprop-2-enamide chemical structure, C23H20ClNO2, CAS 431926-67-9
(E)-3-(2-Chlorophenyl)-N-(4-ethoxyphenyl)-2-phenylprop-2-enamide
CAS 431926-67-9C23H20ClNO2
Ethyl 4-{[3-(2-chlorophenyl)-2-phenylprop-2-enoyl]amino}benzoate chemical structure, C24H20ClNO3, CAS 732249-26-2
Ethyl 4-{[3-(2-chlorophenyl)-2-phenylprop-2-enoyl]amino}benzoate
CAS 732249-26-2C24H20ClNO3
4-[[(Z)-2-(3-Methylphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride chemical structure, C22H17FN2O5S, CAS 21316-13-2
4-[[(Z)-2-(3-Methylphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride
CAS 21316-13-2C22H17FN2O5S
4-[[(Z)-2-(4-Methylphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride chemical structure, C22H17FN2O5S, CAS 21316-14-3
4-[[(Z)-2-(4-Methylphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride
CAS 21316-14-3C22H17FN2O5S
4-[[(Z)-2-(2-Methylphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride chemical structure, C22H17FN2O5S, CAS 21316-12-1
4-[[(Z)-2-(2-Methylphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride
CAS 21316-12-1C22H17FN2O5S
4-[[(Z)-2-(3-Methoxyphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride chemical structure, C22H17FN2O6S, CAS 21970-49-0
4-[[(Z)-2-(3-Methoxyphenyl)-3-(4-nitrophenyl)prop-2-enoyl]amino]benzenesulfonyl fluoride
CAS 21970-49-0C22H17FN2O6S