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Murcko scaffold

Ring system with 3 rings and 25 atoms

41 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
41
With full pages
8
Scaffold SMILES

O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

4-Chloro-N-(4-ethoxyphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C22H27ClN2O4S, CAS 361197-52-6
4-Chloro-N-(4-ethoxyphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 361197-52-6C22H27ClN2O4S
N-(3-Chloro-4-methoxyphenyl)-4-methyl-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide chemical structure, C21H25ClN2O4S, CAS 352559-64-9
N-(3-Chloro-4-methoxyphenyl)-4-methyl-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide
CAS 352559-64-9C21H25ClN2O4S
N-(3,4-Dimethoxyphenyl)-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide chemical structure, C21H26N2O5S, CAS 333450-70-7
N-(3,4-Dimethoxyphenyl)-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide
CAS 333450-70-7C21H26N2O5S
N-(3,5-Dichlorophenyl)-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide chemical structure, C19H20Cl2N2O3S, CAS 494205-10-6
N-(3,5-Dichlorophenyl)-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide
CAS 494205-10-6C19H20Cl2N2O3S
N-(4-Chlorophenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H25ClN2O3S, CAS 425681-46-5
N-(4-Chlorophenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 425681-46-5C21H25ClN2O3S
N-(3,5-Dimethylphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C22H28N2O3S, CAS 591723-25-0
N-(3,5-Dimethylphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 591723-25-0C22H28N2O3S
Ethyl 1-{N-(2,3-dimethylphenyl)-N-[(4-methylphenyl)sulfonyl]glycyl}piperidine-4-carboxylate chemical structure, C25H32N2O5S, CAS 532415-29-5
Ethyl 1-{N-(2,3-dimethylphenyl)-N-[(4-methylphenyl)sulfonyl]glycyl}piperidine-4-carboxylate
CAS 532415-29-5C25H32N2O5S
N-(4-Ethoxyphenyl)-3,4-dimethoxy-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide chemical structure, C23H30N2O6S, CAS 461652-73-3
N-(4-Ethoxyphenyl)-3,4-dimethoxy-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide
CAS 461652-73-3C23H30N2O6S
1-[2-(4-Chloro-N-(4-methylphenyl)sulfonylanilino)acetyl]piperidine-4-carboxamide chemical structure, C21H24ClN3O4S, CAS 510756-18-0
1-[2-(4-Chloro-N-(4-methylphenyl)sulfonylanilino)acetyl]piperidine-4-carboxamide
CAS 510756-18-0C21H24ClN3O4S
Ethyl 1-[N-(4-methylphenyl)-N-{[4-(methylsulfanyl)phenyl]sulfonyl}glycyl]piperidine-4-carboxylate chemical structure, C24H30N2O5S2, CAS 461653-31-6
Ethyl 1-[N-(4-methylphenyl)-N-{[4-(methylsulfanyl)phenyl]sulfonyl}glycyl]piperidine-4-carboxylate
CAS 461653-31-6C24H30N2O5S2
Ethyl 1-{N-(4-chlorophenyl)-N-[(4-methoxyphenyl)sulfonyl]glycyl}piperidine-4-carboxylate chemical structure, C23H27ClN2O6S, CAS 461648-38-4
Ethyl 1-{N-(4-chlorophenyl)-N-[(4-methoxyphenyl)sulfonyl]glycyl}piperidine-4-carboxylate
CAS 461648-38-4C23H27ClN2O6S
1-[2-[N-(4-Methylphenyl)sulfonyl-3-(trifluoromethyl)anilino]acetyl]piperidine-4-carboxamide chemical structure, C22H24F3N3O4S, CAS 461648-60-2
1-[2-[N-(4-Methylphenyl)sulfonyl-3-(trifluoromethyl)anilino]acetyl]piperidine-4-carboxamide
CAS 461648-60-2C22H24F3N3O4S
N-(4-Fluorophenyl)-3,4-dimethoxy-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide chemical structure, C21H25FN2O5S, CAS 693812-86-1
N-(4-Fluorophenyl)-3,4-dimethoxy-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide
CAS 693812-86-1C21H25FN2O5S
1-[2-(N-(4-Fluorophenyl)sulfonyl-4-methoxyanilino)acetyl]piperidine-4-carboxamide chemical structure, C21H24FN3O5S, CAS 701275-11-8
1-[2-(N-(4-Fluorophenyl)sulfonyl-4-methoxyanilino)acetyl]piperidine-4-carboxamide
CAS 701275-11-8C21H24FN3O5S
N-(3,4-Dimethoxyphenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C23H30N2O5S, CAS 425657-63-2
N-(3,4-Dimethoxyphenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 425657-63-2C23H30N2O5S
N-(3-Methoxyphenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C22H28N2O4S, CAS 335208-23-6
N-(3-Methoxyphenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 335208-23-6C22H28N2O4S
N-(2-Chlorophenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H25ClN2O3S, CAS 333745-60-1
N-(2-Chlorophenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 333745-60-1C21H25ClN2O3S
N-(3-Methoxyphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H26N2O4S, CAS 426224-46-6
N-(3-Methoxyphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 426224-46-6C21H26N2O4S
4-Methoxy-N-(4-methylphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C22H28N2O4S, CAS 432512-98-6
4-Methoxy-N-(4-methylphenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 432512-98-6C22H28N2O4S
4-Ethoxy-N-[2-oxo-2-(piperidin-1-yl)ethyl]-N-phenylbenzenesulfonamide chemical structure, C21H26N2O4S, CAS 432003-08-2
4-Ethoxy-N-[2-oxo-2-(piperidin-1-yl)ethyl]-N-phenylbenzenesulfonamide
CAS 432003-08-2C21H26N2O4S
N-(2-Ethylphenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C23H30N2O3S, CAS 361199-58-8
N-(2-Ethylphenyl)-4-methyl-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 361199-58-8C23H30N2O3S
4-Chloro-N-(2-ethoxyphenyl)-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide chemical structure, C21H25ClN2O4S, CAS 693797-71-6
4-Chloro-N-(2-ethoxyphenyl)-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide
CAS 693797-71-6C21H25ClN2O4S
N-(4-Iodophenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H23IN2O3S, CAS 680207-47-0
N-(4-Iodophenyl)-N-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 680207-47-0C20H23IN2O3S
N-(2,3-Dimethylphenyl)-4-methyl-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide chemical structure, C22H28N2O3S, CAS 535942-66-6
N-(2,3-Dimethylphenyl)-4-methyl-N-(2-oxo-2-piperidin-1-ylethyl)benzenesulfonamide
CAS 535942-66-6C22H28N2O3S