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Murcko scaffold

Ring system with 3 rings and 19 atoms

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
22
With full pages
4
Scaffold SMILES

O=C(c1cc2ccccc2oc1=O)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cc2ccccc2oc1=O)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

RefChem:345364 chemical structure, C16H18N2O4, CAS 5651-23-0
RefChem:345364
CAS 5651-23-0C16H18N2O4
4-(8-Allyl-2-oxo-2H-chromene-3-carbonyl)-piperazine-1-carboxylic acid ethyl ester chemical structure, C20H22N2O5, CAS 325779-20-2
4-(8-Allyl-2-oxo-2H-chromene-3-carbonyl)-piperazine-1-carboxylic acid ethyl ester
CAS 325779-20-2C20H22N2O5
3-(4-Methyl-piperazine-1-carbonyl)-chromen-2-one chemical structure, C15H16N2O3, CAS 324067-20-1
3-(4-Methyl-piperazine-1-carbonyl)-chromen-2-one
CAS 324067-20-1C15H16N2O3
Ethyl 4-(2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate chemical structure, C17H18N2O5, CAS 325779-19-9
Ethyl 4-(2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate
CAS 325779-19-9C17H18N2O5
3-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)-8-methoxy-2H-chromen-2-one chemical structure, C17H20N2O5, CAS 421573-84-4
3-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)-8-methoxy-2H-chromen-2-one
CAS 421573-84-4C17H20N2O5
3-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)-6-methoxy-2H-chromen-2-one chemical structure, C17H20N2O5, CAS 431068-01-8
3-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)-6-methoxy-2H-chromen-2-one
CAS 431068-01-8C17H20N2O5
8-Methoxy-3-[(4-methylpiperazinyl)carbonyl]chromen-2-one chemical structure, C16H18N2O4, CAS 313402-67-4
8-Methoxy-3-[(4-methylpiperazinyl)carbonyl]chromen-2-one
CAS 313402-67-4C16H18N2O4
Ethyl 4-(6,8-dibromo-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate chemical structure, C17H16Br2N2O5, CAS 667891-47-6
Ethyl 4-(6,8-dibromo-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate
CAS 667891-47-6C17H16Br2N2O5
Ethyl 4-(6-bromo-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate chemical structure, C17H17BrN2O5, CAS 663929-91-7
Ethyl 4-(6-bromo-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate
CAS 663929-91-7C17H17BrN2O5
Ethyl 4-(6-methoxy-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate chemical structure, C18H20N2O6, CAS 325779-21-3
Ethyl 4-(6-methoxy-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate
CAS 325779-21-3C18H20N2O6
Ethyl 4-(8-methoxy-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate chemical structure, C18H20N2O6, CAS 325779-22-4
Ethyl 4-(8-methoxy-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate
CAS 325779-22-4C18H20N2O6
3-[(4-Ethylpiperazinyl)carbonyl]-8-methoxychromen-2-one chemical structure, C17H20N2O4, CAS 445014-91-5
3-[(4-Ethylpiperazinyl)carbonyl]-8-methoxychromen-2-one
CAS 445014-91-5C17H20N2O4
3-(4-Ethylpiperazine-1-carbonyl)-6-nitro-2H-chromen-2-one chemical structure, C16H17N3O5, CAS 838843-35-9
3-(4-Ethylpiperazine-1-carbonyl)-6-nitro-2H-chromen-2-one
CAS 838843-35-9C16H17N3O5
Ethyl 4-(6-nitro-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate chemical structure, C17H17N3O7, CAS 325779-23-5
Ethyl 4-(6-nitro-2-oxo-2H-chromene-3-carbonyl)piperazine-1-carboxylate
CAS 325779-23-5C17H17N3O7
8-Methoxy-3-(4-(2-methylallyl)piperazine-1-carbonyl)-6-nitro-2H-chromen-2-one chemical structure, C19H21N3O6, CAS 868214-99-7
8-Methoxy-3-(4-(2-methylallyl)piperazine-1-carbonyl)-6-nitro-2H-chromen-2-one
CAS 868214-99-7C19H21N3O6
3-(4-Methylpiperazine-1-carbonyl)-6-nitro-2H-chromen-2-one chemical structure, C15H15N3O5, CAS 325779-64-4
3-(4-Methylpiperazine-1-carbonyl)-6-nitro-2H-chromen-2-one
CAS 325779-64-4C15H15N3O5
3-(4-(2-Methylallyl)piperazine-1-carbonyl)-6-nitro-2H-chromen-2-one chemical structure, C18H19N3O5, CAS 873857-42-2
3-(4-(2-Methylallyl)piperazine-1-carbonyl)-6-nitro-2H-chromen-2-one
CAS 873857-42-2C18H19N3O5
3-(4-Ethylpiperazine-1-carbonyl)chromen-2-one chemical structure, C16H18N2O3, CAS 354546-65-9
3-(4-Ethylpiperazine-1-carbonyl)chromen-2-one
CAS 354546-65-9C16H18N2O3
3-(4-Ethylpiperazine-1-carbonyl)-7-propoxy-2H-1-benzopyran-2-one chemical structure, C19H24N2O4, CAS 7047-62-3
3-(4-Ethylpiperazine-1-carbonyl)-7-propoxy-2H-1-benzopyran-2-one
CAS 7047-62-3C19H24N2O4
6-Methoxy-3-[4-(2-methylprop-2-enyl)piperazine-1-carbonyl]chromen-2-one chemical structure, C19H22N2O4, CAS 915868-21-2
6-Methoxy-3-[4-(2-methylprop-2-enyl)piperazine-1-carbonyl]chromen-2-one
CAS 915868-21-2C19H22N2O4
6-Bromo-8-methoxy-3-[4-(2-methylprop-2-enyl)piperazine-1-carbonyl]chromen-2-one chemical structure, C19H21BrN2O4, CAS 915874-10-1
6-Bromo-8-methoxy-3-[4-(2-methylprop-2-enyl)piperazine-1-carbonyl]chromen-2-one
CAS 915874-10-1C19H21BrN2O4
7-Hydroxy-3-(piperazine-1-carbonyl)-2H-chromen-2-one 2,2,2-trifluoroacetic acid chemical structure, C16H15F3N2O6, CAS 1246818-90-5
7-Hydroxy-3-(piperazine-1-carbonyl)-2H-chromen-2-one 2,2,2-trifluoroacetic acid
CAS 1246818-90-5C16H15F3N2O6