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Murcko scaffold

Ring system with 2 rings and 19 atoms

510 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
510
With full pages
255
Scaffold SMILES

O=C(COc1ccccc1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 481 to 510 of 510 chemicals

N'-(4-Hydroxy-3-methoxybenzylidene)-2-(4-nitrophenoxy)propanohydrazide chemical structure, C17H17N3O6, CAS 303086-34-2
N'-(4-Hydroxy-3-methoxybenzylidene)-2-(4-nitrophenoxy)propanohydrazide
CAS 303086-34-2C17H17N3O6
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(2-methylphenoxy)acetohydrazide chemical structure, C18H20N2O4, CAS 349463-85-0
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(2-methylphenoxy)acetohydrazide
CAS 349463-85-0C18H20N2O4
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-phenoxyacetohydrazide chemical structure, C17H18N2O4, CAS 316143-41-6
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-phenoxyacetohydrazide
CAS 316143-41-6C17H18N2O4
N'-(4-Hydroxy-3-methoxybenzylidene)-2-(3-methylphenoxy)acetohydrazide chemical structure, C17H18N2O4, CAS 94822-44-3
N'-(4-Hydroxy-3-methoxybenzylidene)-2-(3-methylphenoxy)acetohydrazide
CAS 94822-44-3C17H18N2O4
N'-(5-Bromo-2-hydroxybenzylidene)-2-(2-methylphenoxy)acetohydrazide chemical structure, C16H15BrN2O3, CAS 302947-79-1
N'-(5-Bromo-2-hydroxybenzylidene)-2-(2-methylphenoxy)acetohydrazide
CAS 302947-79-1C16H15BrN2O3
N'-(2,4-Dihydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide chemical structure, C19H22N2O4, CAS 303083-63-8
N'-(2,4-Dihydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide
CAS 303083-63-8C19H22N2O4
2-(4-Butoxyphenoxy)-N'-(2-hydroxybenzylidene)acetohydrazide chemical structure, C19H22N2O4, CAS 303086-67-1
2-(4-Butoxyphenoxy)-N'-(2-hydroxybenzylidene)acetohydrazide
CAS 303086-67-1C19H22N2O4
2-(3-Chlorophenoxy)-N'-(3-ethoxy-4-hydroxybenzylidene)propanohydrazide chemical structure, C18H19ClN2O4, CAS 769151-06-6
2-(3-Chlorophenoxy)-N'-(3-ethoxy-4-hydroxybenzylidene)propanohydrazide
CAS 769151-06-6C18H19ClN2O4
2-(2-Allylphenoxy)-N'-(3-ethoxy-4-hydroxybenzylidene)acetohydrazide chemical structure, C20H22N2O4, CAS 769150-96-1
2-(2-Allylphenoxy)-N'-(3-ethoxy-4-hydroxybenzylidene)acetohydrazide
CAS 769150-96-1C20H22N2O4
2-(4-Butoxyphenoxy)-N'-(3-ethoxy-4-hydroxybenzylidene)acetohydrazide chemical structure, C21H26N2O5, CAS 765910-85-8
2-(4-Butoxyphenoxy)-N'-(3-ethoxy-4-hydroxybenzylidene)acetohydrazide
CAS 765910-85-8C21H26N2O5
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(4-nitrophenoxy)propanohydrazide chemical structure, C18H19N3O6, CAS 769150-92-7
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(4-nitrophenoxy)propanohydrazide
CAS 769150-92-7C18H19N3O6
N'-(3-Allyl-2-hydroxybenzylidene)-2-(2-chlorophenoxy)acetohydrazide chemical structure, C18H17ClN2O3, CAS 477731-51-4
N'-(3-Allyl-2-hydroxybenzylidene)-2-(2-chlorophenoxy)acetohydrazide
CAS 477731-51-4C18H17ClN2O3
2-(4-Butoxyphenoxy)-N'-(4-hydroxy-3-methoxybenzylidene)acetohydrazide chemical structure, C20H24N2O5, CAS 303087-48-1
2-(4-Butoxyphenoxy)-N'-(4-hydroxy-3-methoxybenzylidene)acetohydrazide
CAS 303087-48-1C20H24N2O5
2-(4-Chlorophenoxy)-N'-(2,4-dihydroxybenzylidene)propanohydrazide chemical structure, C16H15ClN2O4, CAS 303064-37-1
2-(4-Chlorophenoxy)-N'-(2,4-dihydroxybenzylidene)propanohydrazide
CAS 303064-37-1C16H15ClN2O4
N'-(4-Hydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide chemical structure, C19H22N2O3, CAS 303084-08-4
N'-(4-Hydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide
CAS 303084-08-4C19H22N2O3
2-(4-Chlorophenoxy)-N'-(4-hydroxybenzylidene)propanohydrazide chemical structure, C16H15ClN2O3, CAS 301309-20-6
2-(4-Chlorophenoxy)-N'-(4-hydroxybenzylidene)propanohydrazide
CAS 301309-20-6C16H15ClN2O3
2-(2,3-Dichlorophenoxy)-N'-(4-hydroxybenzylidene)acetohydrazide chemical structure, C15H12Cl2N2O3, CAS 477731-00-3
2-(2,3-Dichlorophenoxy)-N'-(4-hydroxybenzylidene)acetohydrazide
CAS 477731-00-3C15H12Cl2N2O3
N'-(4-Hydroxybenzylidene)-2-phenoxyacetohydrazide chemical structure, C15H14N2O3, CAS 303088-05-3
N'-(4-Hydroxybenzylidene)-2-phenoxyacetohydrazide
CAS 303088-05-3C15H14N2O3
(Z)-N'-(4-Hydroxybenzylidene)-2-phenoxypropanehydrazide chemical structure, C16H16N2O3, CAS 300590-70-9
(Z)-N'-(4-Hydroxybenzylidene)-2-phenoxypropanehydrazide
CAS 300590-70-9C16H16N2O3
N'-(2-Hydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide chemical structure, C19H22N2O3, CAS 303086-78-4
N'-(2-Hydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide
CAS 303086-78-4C19H22N2O3
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide chemical structure, C21H26N2O4, CAS 769148-30-3
N'-(3-Ethoxy-4-hydroxybenzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide
CAS 769148-30-3C21H26N2O4
2-(4-(tert-Butyl)phenoxy)-N'-(3-ethoxy-4-hydroxy-5-iodobenzylidene)acetohydrazide chemical structure, C21H25IN2O4, CAS 865857-32-5
2-(4-(tert-Butyl)phenoxy)-N'-(3-ethoxy-4-hydroxy-5-iodobenzylidene)acetohydrazide
CAS 865857-32-5C21H25IN2O4
2-(4-Bromophenoxy)-N'-[(E)-(3-ethoxy-4-hydroxyphenyl)methylidene]propanohydrazide chemical structure, C18H19BrN2O4, CAS 767333-91-5
2-(4-Bromophenoxy)-N'-[(E)-(3-ethoxy-4-hydroxyphenyl)methylidene]propanohydrazide
CAS 767333-91-5C18H19BrN2O4
2-(4-Chloro-2-methylphenoxy)-N'-(2-(trifluoromethoxy)benzylidene)acetohydrazide chemical structure, C17H14ClF3N2O3, CAS 2412897-12-0
2-(4-Chloro-2-methylphenoxy)-N'-(2-(trifluoromethoxy)benzylidene)acetohydrazide
CAS 2412897-12-0C17H14ClF3N2O3