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Murcko scaffold

2-(Pyrrolidin-1-yl)thiazole scaffold

137 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
137
With full pages
9
Scaffold SMILES

c1csc(N2CCCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-1-yl)thiazole page
Murcko scaffold c1csc(N2CCCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 137 chemicals

Methyl 4-amino-2-(pyrrolidin-1-yl)thiazole-5-carboxylate chemical structure, C9H13N3O2S, CAS 99967-76-7
Methyl 4-amino-2-(pyrrolidin-1-yl)thiazole-5-carboxylate
CAS 99967-76-7C9H13N3O2S
4-Methyl-2-(pyrrolidin-1-yl)-1,3-thiazole chemical structure, C8H12N2S, CAS 164397-14-2
4-Methyl-2-(pyrrolidin-1-yl)-1,3-thiazole
CAS 164397-14-2C8H12N2S
2-(Pyrrolidin-1-yl)thiazole chemical structure, C7H10N2S, CAS 24255-45-6
2-(Pyrrolidin-1-yl)thiazole
CAS 24255-45-6C7H10N2S
4-Chloro-2-(pyrrolidin-1-yl)thiazole-5-carbaldehyde chemical structure, C8H9ClN2OS, CAS 175543-06-3
4-Chloro-2-(pyrrolidin-1-yl)thiazole-5-carbaldehyde
CAS 175543-06-3C8H9ClN2OS
2-Pyrrolidin-1-yl-1,3-thiazole-5-carbaldehyde chemical structure, C8H10N2OS, CAS 900015-48-7
2-Pyrrolidin-1-yl-1,3-thiazole-5-carbaldehyde
CAS 900015-48-7C8H10N2OS
Ethyl 2-(pyrrolidin-1-yl)thiazole-4-carboxylate chemical structure, C10H14N2O2S, CAS 162739-99-3
Ethyl 2-(pyrrolidin-1-yl)thiazole-4-carboxylate
CAS 162739-99-3C10H14N2O2S
Thiazole, 4-(chloromethyl)-2-(1-pyrrolidinyl)- chemical structure, C8H11ClN2S, CAS 172649-59-1
Thiazole, 4-(chloromethyl)-2-(1-pyrrolidinyl)-
CAS 172649-59-1C8H11ClN2S
(1-(Thiazol-2-yl)pyrrolidin-2-yl)methanol chemical structure, C8H12N2OS, CAS 1247916-45-5
(1-(Thiazol-2-yl)pyrrolidin-2-yl)methanol
CAS 1247916-45-5C8H12N2OS
Ethyl 4-methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylate chemical structure, C11H16N2O2S, CAS 950269-69-9
Ethyl 4-methyl-2-pyrrolidin-1-yl-1,3-thiazole-5-carboxylate
CAS 950269-69-9C11H16N2O2S
[1-(4,5-Dimethyl-1,3-thiazol-2-yl)pyrrolidin-2-yl]methanol chemical structure, C10H16N2OS, CAS 1467206-03-6
[1-(4,5-Dimethyl-1,3-thiazol-2-yl)pyrrolidin-2-yl]methanol
CAS 1467206-03-6C10H16N2OS
1-(Thiazol-2-yl)pyrrolidin-3-ol chemical structure, C7H10N2OS, CAS 1342562-45-1
1-(Thiazol-2-yl)pyrrolidin-3-ol
CAS 1342562-45-1C7H10N2OS
2-(Pyrrolidin-1-yl)thiazole-5-carboxylic acid chemical structure, C8H10N2O2S, CAS 941716-91-2
2-(Pyrrolidin-1-yl)thiazole-5-carboxylic acid
CAS 941716-91-2C8H10N2O2S
1-(2-Thiazolyl)-3-pyrrolidinemethanamine chemical structure, C8H13N3S, CAS 933748-99-3
1-(2-Thiazolyl)-3-pyrrolidinemethanamine
CAS 933748-99-3C8H13N3S
Ethyl 2-(pyrrolidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate chemical structure, C11H13F3N2O2S, CAS 1000339-79-6
Ethyl 2-(pyrrolidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate
CAS 1000339-79-6C11H13F3N2O2S
2-[2-(Pyrrolidin-1-yl)-1,3-thiazol-4-yl]ethan-1-amine chemical structure, C9H15N3S, CAS 1018295-48-1
2-[2-(Pyrrolidin-1-yl)-1,3-thiazol-4-yl]ethan-1-amine
CAS 1018295-48-1C9H15N3S
(2S)-1-(1,3-Thiazol-2-yl)pyrrolidine-2-carboxylic acid chemical structure, C8H10N2O2S, CAS 1104577-35-6
(2S)-1-(1,3-Thiazol-2-yl)pyrrolidine-2-carboxylic acid
CAS 1104577-35-6C8H10N2O2S
2-(Pyrrolidin-1-yl)thiazol-4-amine chemical structure, C7H11N3S, CAS 849091-89-0
2-(Pyrrolidin-1-yl)thiazol-4-amine
CAS 849091-89-0C7H11N3S
4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid chemical structure, C9H12N2O2S, CAS 947013-57-2
4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid
CAS 947013-57-2C9H12N2O2S
Potassium 1-(1,3-thiazol-2-yl)pyrrolidine-2-carboxylate chemical structure, C8H9KN2O2S, CAS 1231949-74-8
Potassium 1-(1,3-thiazol-2-yl)pyrrolidine-2-carboxylate
CAS 1231949-74-8C8H9KN2O2S
4-Bromo-2-(pyrrolidin-1-yl)-1,3-thiazole chemical structure, C7H9BrN2S, CAS 1017781-56-4
4-Bromo-2-(pyrrolidin-1-yl)-1,3-thiazole
CAS 1017781-56-4C7H9BrN2S
4-Bromo-2-(3-hydroxypyrrolidino)thiazole chemical structure, C7H9BrN2OS, CAS 959237-57-1
4-Bromo-2-(3-hydroxypyrrolidino)thiazole
CAS 959237-57-1C7H9BrN2OS
5-Bromo-2-(1-pyrrolidinyl)thiazole chemical structure, C7H9BrN2S, CAS 933696-74-3
5-Bromo-2-(1-pyrrolidinyl)thiazole
CAS 933696-74-3C7H9BrN2S
5-Bromo-2-(3-hydroxypyrrolidin-1-yl)thiazole chemical structure, C7H9BrN2OS, CAS 959239-94-2
5-Bromo-2-(3-hydroxypyrrolidin-1-yl)thiazole
CAS 959239-94-2C7H9BrN2OS
(2-(Pyrrolidin-1-yl)thiazol-4-yl)methanamine chemical structure, C8H13N3S, CAS 1209952-47-5
(2-(Pyrrolidin-1-yl)thiazol-4-yl)methanamine
CAS 1209952-47-5C8H13N3S