CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 15 atoms

36 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
36
With full pages
11
Scaffold SMILES

c1ccc(-c2ccn3ncnc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccn3ncnc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

5-(4-Methoxyphenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H9F3N4O, CAS 361368-95-8
5-(4-Methoxyphenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine
CAS 361368-95-8C13H9F3N4O
5-Phenyl-7-(trifluoromethyl)(1,2,4)triazolo(1,5-a)pyrimidin-2-amine chemical structure, C12H8F3N5, CAS 304687-29-4
5-Phenyl-7-(trifluoromethyl)(1,2,4)triazolo(1,5-a)pyrimidin-2-amine
CAS 304687-29-4C12H8F3N5
5-Phenyl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H7F3N4, CAS 299405-35-9
5-Phenyl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 299405-35-9C12H7F3N4
5-(4-Methylphenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H9F3N4, CAS 333765-70-1
5-(4-Methylphenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine
CAS 333765-70-1C13H9F3N4
5-(4-Chlorophenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H6ClF3N4, CAS 690698-03-4
5-(4-Chlorophenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 690698-03-4C12H6ClF3N4
5-(3-Methoxyphenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H10F3N5O, CAS 713508-33-9
5-(3-Methoxyphenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 713508-33-9C13H10F3N5O
2-Fluoro-4-[6-methyl-2-(methylsulfanyl)[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]phenyl methyl ether chemical structure, C14H13FN4OS, CAS 861210-14-2
2-Fluoro-4-[6-methyl-2-(methylsulfanyl)[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]phenyl methyl ether
CAS 861210-14-2C14H13FN4OS
2-(Methylsulfanyl)-5-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H9F3N4S, CAS 866019-43-4
2-(Methylsulfanyl)-5-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidine
CAS 866019-43-4C13H9F3N4S
5-[3-(Trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H7F3N4, CAS 75175-86-9
5-[3-(Trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidine
CAS 75175-86-9C12H7F3N4
5-(4-Bromophenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H6BrF3N4, CAS 511309-04-9
5-(4-Bromophenyl)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine
CAS 511309-04-9C12H6BrF3N4
5-(3-Fluoro-4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H12FN5O, CAS 861207-38-7
5-(3-Fluoro-4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 861207-38-7C13H12FN5O
5-(3-Fluoro-4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H11FN4O, CAS 861207-30-9
5-(3-Fluoro-4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 861207-30-9C13H11FN4O
7-(Difluoromethyl)-5-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C14H12F2N4O2, CAS 832135-67-8
7-(Difluoromethyl)-5-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 832135-67-8C14H12F2N4O2
7-(Difluoromethyl)-5-(4-fluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H7F3N4, CAS 832136-68-2
7-(Difluoromethyl)-5-(4-fluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine
CAS 832136-68-2C12H7F3N4
7-Chloro-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C11H7ClN4, CAS 28565-43-7
7-Chloro-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 28565-43-7C11H7ClN4
7-Methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H10N4, CAS 142954-86-7
7-Methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 142954-86-7C12H10N4
7-Methyl-5-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C12H11N5, CAS 72966-18-8
7-Methyl-5-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 72966-18-8C12H11N5
5-(3,4-Dichlorophenyl)-7-(difluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H6Cl2F2N4, CAS 832138-36-0
5-(3,4-Dichlorophenyl)-7-(difluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine
CAS 832138-36-0C12H6Cl2F2N4
7-Chloro-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C12H6ClF3N4, CAS 75175-85-8
7-Chloro-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 75175-85-8C12H6ClF3N4
5-(3,4-Dimethoxyphenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C14H12F3N5O2, CAS 893615-43-5
5-(3,4-Dimethoxyphenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 893615-43-5C14H12F3N5O2
7-(Difluoromethyl)-5-(4-methoxyphenyl)[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C14H10F2N4O3, CAS 1018053-78-5
7-(Difluoromethyl)-5-(4-methoxyphenyl)[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 1018053-78-5C14H10F2N4O3
5-(4-Chlorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C12H7ClN4O2, CAS 1018143-17-3
5-(4-Chlorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 1018143-17-3C12H7ClN4O2
5-(4-Fluorophenyl)-(1,2,4)triazolo(1,5-a)pyrimidine-7-carboxylic acid chemical structure, C12H7FN4O2, CAS 1018143-24-2
5-(4-Fluorophenyl)-(1,2,4)triazolo(1,5-a)pyrimidine-7-carboxylic acid
CAS 1018143-24-2C12H7FN4O2
5-(3-Nitrophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C12H7N5O4, CAS 1018125-21-7
5-(3-Nitrophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 1018125-21-7C12H7N5O4